Genomic analysis of Isometamidium Chloride resistance in Trypanosoma congolense [PDF]
International Journal for Parasitology: Drugs and Drug Resistance, 2017 Isometamidium Chloride (ISM) is one of the principal drugs used to counteract Trypanosoma congolense infection in livestock, both as a prophylactic as well as a curative treatment. However, numerous cases of ISM resistance have been reported in different
Eliane Tihon +5 more
doaj +4 more sources
The economic cost of bovine trypanosomosis in pastoral and ago pastoral communities surrounding Murchision Falls National park, Buliisa district, Uganda [PDF]
BMC Veterinary Research, 2022 Background: Animal diseases that are endemic like tsetse transmitted trypanosomosis cause the continuous expenditure of financial resources of livestock farmers and loss of productivity of livestock.
Daniel Kizza +8 more
doaj +2 more sources
Systematic Review and Meta-Analysis on Knowledge Attitude and Practices on African Animal Trypanocide Resistance [PDF]
Tropical Medicine and Infectious Disease, 2022 Background: African trypanocide resistance is an emerging public health emergency whose control requires a revisit on farmer’s knowledge, attitudes, and practices in developing countries.
Keneth Iceland Kasozi +5 more
doaj +2 more sources
Laboratory and Field Evaluation of Biodegradable Polyesters for Sustained Release of Isometamidium and Ethidium [PDF]
Memorias do Instituto Oswaldo Cruz, 1999 An overview is presented of the results obtained with biodegradable sustained release devices (SRDs) containing a mixture of polymers and either isometamidium (ISMM) or ethidium. Under controlled laboratory conditions (monthly challenge with tsetse flies
S Geerts, JRA Brandt, R De Deken
doaj +4 more sources
Chemosensitization of Trypanosoma congolense strains resistant to isometamidium chloride by tetracyclines and enrofloxacin. [PDF]
PLoS Neglected Tropical Diseases, 2010 BACKGROUND: Because of the development of resistance in trypanosomes to trypanocidal drugs, the livelihood of millions of livestock keepers in sub-Saharan Africa is threatened now more than ever.
Vincent Delespaux +7 more
doaj +6 more sources
Trypanocide Use and Molecular Characterization of Trypanosomes Resistant to Diminazene Aceturate in Cattle in Northern Côte D’Ivoire [PDF]
Tropical Medicine and Infectious DiseaseThe resistance of trypanosomes to the doses of trypanocide administered by farmers to their animals acts as a real brake on efforts to control to combat African trypanosomiasis.
Jean-Yves Ekra +6 more
doaj +2 more sources
Longitudinal observational (single cohort) study on the causes of trypanocide failure in cases of African animal trypanosomosis in cattle near wildlife protected areas of Northern Tanzania. [PDF]
PLoS Neglected Tropical DiseasesAfrican animal trypanosomosis (AAT) in cattle is primarily managed through trypanocide administration and insecticide application. Trypanocides can be used for both treatment and prophylaxis, but failure is often reported; this may occur due to ...
Shauna Richards +13 more
doaj +2 more sources
Prothidium and isometamidium as drug against Trypanosoma brucei canine trypanosomiasis
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1970 Le Prothidium et l'Isométamidium ont été utilisés dans le traitement de plusieurs cas de trypanosomiase expérimentale du chien à Trypanosoma brucei. Le Prothidium est administré à raison de 2 mg/kg de la solution à 2 p.100 et l'Isométamidium 1 mg/kg de ...
Saydil Touré
doaj +3 more sources
Equine trypanosomiasis, a systematic review: Disease management. [PDF]
Equine Vet JAbstract Background Equine trypanosomiasis is a neglected protozoal disease. Objectives To answer the study question: In equines what are the effects of disease management of trypanosomiasis on disease severity (individual level) and disease prevalence (population level) compared to no intervention? Study Design Systematic review.
Raftery AG +5 more
europepmc +2 more sources
Pathogenic Significance of Trypanosomatids: Progress in Drug Resistance, Control Strategies, and Artificial Intelligence. [PDF]
Interdiscip Perspect Infect DisTrypanosomatids, including the genera Trypanosoma and Leishmania, are protozoan parasites of significant medical and veterinary relevance. These organisms cause African trypanosomiasis, Chagas disease, and leishmaniasis, which are classified as neglected tropical diseases (NTDs).
Amisigo CM +12 more
europepmc +2 more sources