Results 1 to 10 of about 484 (116)

HPTLC and HPLC determination of isometamidium in the presence of its manufacturing and degradation impurities

Journal of Pharmaceutical and Biomedical Analysis, 1998
M H Grant, G G Skellern, M H Grant
exaly  

Genomic analysis of Isometamidium Chloride resistance in

International Journal for Parasitology: Drugs and Drug Resistance, 2017
Hideo Imamura, Jan Van Den Abbeele, Jean-Claude Dujardin   +2 more
exaly  

Time-dose response of bloodstream forms to diminazene and isometamidium

Veterinary Parasitology, 1994
R Kaminsky
exaly  

Absence of correlation between karyotype profiles of and resistance to isometamidium chloride

Veterinary Parasitology, 2007
Takehisa Chuma, Francis Shahada, Karoku Okamoto   +2 more
exaly  

French guyanan stock of resistant to diminazene aceturate but sensitive to isometamidium chloride

Acta Tropica, 1995
Andrew S Peregrine, Stéphane de la Rocque, M Desquesnes   +2 more
exaly  

Nanoformulation of a Trypanocidal Drug Isometamidium Chloride Ameliorates the Apurinic-Apyrimidinic DNA Sites/Genotoxic Effects in Horse Blood Cells [PDF]

Journal of Xenobiotics, 2023
Isometamidium chloride (ISM) is a trypanocide for the prophylactic and therapeutic use against vector-borne animal trypanosomosis (mainly Surra caused by Trypanosoma evansi) and African animal trypanosomosis caused by T. congolense/T. vivax/T.
Sandeep Singh, Balvinder Kumar, Neeraj Dilbaghi, Nisha Devi, Minakshi Prasad, Anju Manuja   +5 more
doaj   +2 more sources

A cell surface transporter mediates phenanthridine resistance in African trypanosomes [PDF]

npj Antimicrobials and Resistance
African animal trypanosomosis poses a significant threat to livestock health and agricultural productivity across sub-Saharan Africa. Isometamidium chloride is the only available drug that is both prophylactic and curative.
Pieter C. Steketee, Marzuq A. Ungogo, Edith Paxton, Ella Maria Rogerson, Furaha Mramba, Michael C. Pearce, Harriet K. Auty, Jan Van Den Abbeele, Harry P. de Koning, Catarina Gadelha, Michael P. Barrett, Liam J. Morrison   +11 more
doaj   +3 more sources

Vector competence of sterile male Glossina fuscipes fuscipes for Trypanosoma brucei brucei: implications for the implementation of the sterile insect technique in a sleeping sickness focus in Chad [PDF]

Parasites & Vectors, 2023
Background Human African trypanosomiasis (HAT) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted by tsetse flies in sub-Saharan West Africa. In southern Chad the most active and persistent focus is the Mandoul focus, with
Mahamat Hissene Mahamat, Adeline Ségard, Jean-Baptiste Rayaisse, Rafael Argiles-Herrero, Andrew Gordon Parker, Philippe Solano, Adly Mohamed Mohamed Abd-Alla, Jérémy Bouyer, Sophie Ravel   +8 more
doaj   +2 more sources

Variation of sensitivity of Trypanosoma evansi isolates from Isiolo and Marsabit counties of Kenya to locally available trypanocidal drugs. [PDF]

PLoS ONE, 2023
Trypanocidal resistance is a major cause of treatment failure. This study evaluated the sensitivity of Trypanosoma evansi field isolates collected from Marsabit and Isiolo counties, Kenya. A total of 2,750 camels were screened using parasitological tests
Raymond E Mdachi, Kennedy O Ogolla, Joanna E Auma, Florence N Wamwiri, Richard K Kurgat, Kennedy B Wanjala, Lawrence G Mugunieri, Phylis M Alusi, Judith K Chemuliti, Phoebe W Mukiria, Sylvance O Okoth   +10 more
doaj   +2 more sources

Trypanocide usage in the cattle belt of southwestern Uganda [PDF]

Frontiers in Microbiology, 2023
BackgroundSystematic infrastructure and regulatory weaknesses over many decades, in communities struggling with animal African trypanosomiasis (AAT) would be expected to create an environment that would promote drug misuse and risk development of drug ...
Keneth Iceland Kasozi, Keneth Iceland Kasozi, Ewan Thomas MacLeod, Keith Robert Sones, Keith Robert Sones, Susan Christina Welburn, Susan Christina Welburn   +6 more
doaj   +2 more sources