Results 71 to 80 of about 527 (157)

Comparative experimental studies on Trypanosoma isolates in mice and response to diminazene aceturate and isometamidium chloride treatment

Heliyon, 2018
The current study was undertaken from December 2015 to May 2016 with the aim of determining and comparing the pathogenicity and response to diminazene aceturate (DA) and isometamidium chloride (ISM) treatment in experimentally infected mice with ...
Muluken Yayeh, Shimelis Dagnachew, Meseret Tilahun, Achenef Melaku, Tadegegn Mitiku, Mohamed Yesuf, Zewdu Seyoum, Habtamu Kefyalew   +7 more
doaj   +1 more source

Determination of Residual Isometamidium in Cattle Tissues and Milk by HPLC

Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 1999
A determination method for the antitripanosomal agent, isometamidium (IMD) in cattle muscle, liver, fat and milk has been developed by using HPLC. The drug was extracted from a sample with acetonitrile-0.25mol/L ammonium formate methanol solution, and purified by liquid-liquid partition with ethyl acetate and water, followed by extraction of the water ...
KONDO, Kazunari, HORIE, Masakazu, MURAYAMA, Mitsunori, SUZUKI, Takashi, TOYODA, Masatake   +4 more
openaire   +2 more sources

Effect of Trypanosome Infection on Work Performance of Trypanotolerant Ndama Cattle in Senegal Subhumid Zone

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2002
The aim of this study was to assess trypanosome infection effects on the work performance of trypanotolerant cattle in the subhumid zone of Senegal. The study was conducted on Ndama cattle with a mean live weight of 288 kg and a mean age of six years ...
M. T. Seck, A. Fall, A. Diaite, A. Diokou, M. Dieng   +4 more
doaj   +1 more source

Kinetic modelling of isometamidium chloride (Samorin) uptake byTrypanosoma congolense

Parasitology, 1992
Clones ofTrypanosoma congolensewhich express resistance to the widely used trypanocide isometamidium chloride accumulate less of the drug than clones which are sensitive to drug treatment. A mathematical model has been developed which was able to predict theoretical lines representing the uptake kinetics in trypanosomes which were sensitive to ...
Sutherland, IA, Mounsey, A, Eisler, MC, Holmes, PH   +3 more
openaire   +3 more sources

Study of mRNA expression of thirteen genes of Trypanosoma evansi in response to diminazene aceturate and isometamidium chloride

Indian Journal of Animal Sciences
The monomorphic, non-cyclic, extracellular haemoprotozoan parasite, Trypanosoma evansi leads to Surra disease in domesticated animals. Currently, diminazene aceturate (DA) and isometamidium chloride (ISM) are the most used chemotherapeutic agents for ...
SNEHIL GUPTA, SUKHDEEP VOHRA, KHUSHBOO SETHI, RUMA RANI, SURBHI GUPTA, RAJENDER KUMAR, SANJAY KUMAR   +6 more
doaj   +1 more source

Drug quality analysis of isometamidium chloride hydrochloride and diminazene diaceturate used for the treatment of African animal trypanosomosis in West Africa

BMC Veterinary Research, 2018
Background Diminazene diaceturate (DA) and isometamidium chloride hydrochloride (ISM) are with homidium bromide, the main molecules used to treat African Animal Trypanosomosis (AAT).
Zakaria Bengaly, Sèna Hervé Vitouley, Martin Bienvenu Somda, André Zongo, Assiongbon Têko-Agbo, Giuliano Cecchi, Yahaya Adam, Issa Sidibé, Balé Bayala, Adrien Marie Gaston Belem, Jan Van Den Abbeele, Vincent Delespaux   +11 more
doaj   +1 more source

Clinical and therapeutic aspects of an outbreak of canine trypanosomiasis

Revista Brasileira de Parasitologia Veterinária
Trypanosomiasis caused by Trypanosoma evansi can seriously affect both domestic and wild animals. This article reports on an outbreak of canine trypanosomiasis on a farm in the Pantanal region of Brazil.
Jessica Teles Echeverria, Rodrigo Leite Soares, Beatriz Aléssio Crepaldi, Gustavo Gomes de Oliveira, Polyana Mayume Pereira da Silva, Rayane Chitolina Pupin, Tessie Beck Martins, Herbert Patric Kellermann Cleveland, Carlos Alberto do Nascimento Ramos, Fernando de Almeida Borges   +9 more
doaj   +1 more source

STUDIES ON ISOMETAMIDIUM: THE EFFECT OF ISOMETAMIDIUM, HOMIDIUM AND PYRITHIDIUM ON THE INFECTIVITY OF TRYPANOSOMAS FOR MICE [PDF]

British Journal of Pharmacology and Chemotherapy, 1965
openaire   +2 more sources

Determination of serum isometamidium levels in sheep and goats under field conditions using isometamidium-ELISA

Determination of serum isometamidium levels in sheep and goats under field conditions using isometamidium-ELISA
application/pdf Twenty eight sheep and 28 goats were treated with isometamidium chloride (Samorin®, hone Merieux, Lyon, France) at a dose of 1 mg/kg body weight (bw) by intramuscular injection. All the animals were grazed in a tsetse-infested area.
openaire  

African animal trypanocide resistance: A systematic review and meta-analysis. [PDF]

Front Vet Sci, 2022
Kasozi KI, MacLeod ET, Welburn SC.
europepmc   +1 more source