Results 111 to 120 of about 95,782 (307)

MiR‐1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT MicroRNA‐1 (miR‐1) is a conserved microRNA that is highly expressed in skeletal and cardiac muscle tissues. Moreover, miR‐1 regulates genes and has critical roles in cell migration and invasion. Downregulation of miR‐1 has been found in many pathologies of numerous organs, including the lungs.
Maricica Pacurari   +2 more
wiley   +1 more source

Bilateral rostral mandibulectomy in case of a complete fracture of the pars incisiva in a Simmental fattening bull

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A 9‐month‐old Simmental fattening bull with a history of anorexia, severe salivation and marked bilateral swelling of the mandible was referred to the clinic. The physical examination and radiographs revealed a bilateral complete displaced mandibular fracture involving the symphysis. Treatment consisted of rostral mandibulectomy, including the
Cassandra Eibl   +4 more
wiley   +1 more source

Chronic Cellular NAD Depletion Activates a Viral Infection‐Like Interferon Response Through Mitochondrial DNA Leakage

open access: yesAging Cell, EarlyView.
Chronic NAD depletion in fibroblasts lowers NAD levels, increases mitochondrial mass, and triggers an interferon‐dependent inflammatory response via mtDNA leakage through VDAC1, activating the cGAS‐STING pathway. This links NAD deficiency to metabolic and inflammatory processes, with implications for diseases associated with NAD decline.
Claudia C. S. Chini   +14 more
wiley   +1 more source

Opportunities and Challenges of Population Pharmacogenomics

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou   +3 more
wiley   +1 more source

Neglected intraocular wooden foreign bodies

open access: yesThe Pan African Medical Journal, 2018
A 40-year-old HIV-positive female presented with an erythematous macular eruption involving the malar and periorbital area, the forehead and neck of six weeks of duration (A).
Hanane Oummad, amina Laghmari
doaj   +1 more source

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