Results 111 to 120 of about 97,287 (310)

Sural/Radial Amplitude Ratio: A Useful Tool to Diagnose Non‐Length‐Dependent Neuropathy

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Patients with non‐length‐dependent neuropathy (NLDN) exhibit reduced sensory nerve action potential (SNAP) amplitudes in both lower and upper limbs. This study aimed to determine a threshold for the sural/radial amplitude ratio (SRAR) suggestive of NLDN.
Antoine Pegat   +6 more
wiley   +1 more source

Spectroscopic, X‐Ray Crystallographic, and Hirshfeld Surface Analyses for the Investigation of Intermolecular Interactions in Carboxamide Hydrazone Hybrids

open access: yesChemistryOpen, EarlyView.
Two novel carboxamide hydrazone hybrids are synthesized and characterized. Structural, spectroscopic, and computational analyses reveal dominant hydrogen bonding, π–π stacking, and reactive sites. Compound 2b exhibits potent antibacterial activity against Staphylococcus aureus, highlighting its potential as a cost‐effective therapeutic agent.
Nabila A. Kheder   +6 more
wiley   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

Urban Forests and Environmental Challenges in the Last Decades in Brazil: Insights for the National Urban Forestry Plan

open access: yesSustainable Development, EarlyView.
ABSTRACT National afforestation policies are crucial for outlining guidelines and goals to be implemented at the local level. Therefore, it is crucial to conduct research that systematizes indicators from across the country into a single proposal. This study examines the spatiotemporal distribution of urban forest research in Brazil from 1980 to 2020 ...
Mauricio Lamano Ferreira   +5 more
wiley   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

open access: yesSmall, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy