Results 101 to 110 of about 46,386 (217)
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang +3 more
wiley +1 more source
Mapping IgG epitopes of the major birch allergen Bet v 1 identified patient‐derived, hypoallergenic peptides that did not trigger degranulation. These findings support a novel, safer approach for peptide‐based allergen immunotherapy that leverages naturally induced IgG specificities from allergic individuals. ABSTRACT Background Allergen immunotherapy (
Lara Šošić +10 more
wiley +1 more source
Bullo Saifullah,1 Mohamed Ezzat El Zowalaty,2,3 Palanisamy Arulselvan,3 Sharida Fakurazi,3,4 Thomas J Webster,5–7 Benjamin Mahler Geilich,5,6 Mohd Zobir Hussein1 1Materials Synthesis and Characterization Laboratory, Institute of Advanced ...
Saifullah B +6 more
doaj
ABSTRACT The NAT2 gene encodes N‐acetyltransferase 2, an enzyme critically involved in the biotransformation of numerous xenobiotics and aromatic amines, including isoniazid, a cornerstone drug in tuberculosis therapy. Genetic polymorphisms in NAT2 lead to variable acetylation rates, clinically categorized as poor, intermediate, or rapid metabolizer ...
Nada Benyahya +6 more
wiley +1 more source
Pellagra in Contemporary Clinical Practice (2000–2023): A Systematic Review
This systematic review (2000–2023) of 1212 cases highlights pellagra's evolving etiology. While primary dietary deficiency (85%) persists in humanitarian crises, secondary forms from alcohol misuse (9.6%), isoniazid (14.3% of drug‐related cases), and malabsorption are rising.
Noureddine Litaiem +2 more
wiley +1 more source
Acetylator status-guided rapid reintroduction of isoniazid in tuberculosis patients with drug-induced hepatotoxicity. [PDF]
van Arkel C +8 more
europepmc +1 more source
Based on the clinical characteristics of patients with spinal tuberculosis after percutaneous vertebral augmentation, the corresponding diagnosis and treatment strategies were explored, and clinical data for the differential diagnosis of spinal tuberculosis were provided.
Xiong Xu +10 more
wiley +1 more source
Rapid Eukaryotic Impedimetric Biosensing of Naproxen and Isoniazid: A Proof-of-Concept for Acute Toxicity Monitoring. [PDF]
Štukovnik Z, Perko N, Bren U.
europepmc +1 more source
Fluorinated aminopiperidones, designed as non‐glutarimide thalidomide analogs, were synthesized with full regio‐ and stereocontrol. The C*–CF3 used as carbonyl surrogate improved solubility and membrane interactions while abolishing cereblon binding.
Boštjan Adamlje +11 more
wiley +1 more source

