Results 101 to 110 of about 86,651 (264)

Inhibitory Effect of Antituberculosis Drugs on Human Cytochrome P450-Mediated Activities

open access: yesJournal of Pharmacological Sciences, 2004
The potential for drug-drug interactions mediated by the inhibition of cytochrome P-450 (CYP) were concerned during antituberculosis therapy. However, the information regarding human CYP inhibition by antituberculosis drugs is limited to isoniazid.
Yuki Nishimura   +3 more
doaj   +1 more source

Acneiform dermatoses [PDF]

open access: yes, 1998
Acneiform dermatoses are follicular eruptions. The initial lesion is inflammatory, usually a papule or pustule. Comedones are later secondary lesions, a sequel to encapsulation and healing of the primary abscess.
Jansen, Thomas, Plewig, G.
core   +1 more source

Advances and Current Progress of Dopant Engineering on All‐Inorganic Halide Perovskites Toward High‐Performance Scintillating Materials

open access: yesMetalMat, EarlyView.
This review provides the latest advancement on lead‐free all‐inorganic perovskites, covering fundamental aspects, emerging synthetic routes, and scintillation properties. We highlight the dopant engineering strategy to favor the formation and efficient radiative recombination of self‐trapped excitons and the future development direction for the next ...
Galfin Anderias Adu   +6 more
wiley   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

Impact of isoniazid monoresistance on overall and vulnerable patient populations in Taiwan

open access: yesEmerging Microbes and Infections
Isoniazid is an early bactericidal anti-tuberculosis (TB) agent and isoniazid mono-resistance TB is the most prevalent drug-resistant TB worldwide. Concerns exist regarding whether resistance to isoniazid would lead to delayed culture conversion and ...
Meng-Rui Lee   +5 more
doaj   +1 more source

Isoniazid inhibits the heme-based reactivity of Mycobacterium tuberculosis truncated hemoglobin N.

open access: yesPLoS ONE, 2013
Isoniazid represents a first-line anti-tuberculosis medication in prevention and treatment. This prodrug is activated by a mycobacterial catalase-peroxidase enzyme called KatG in Mycobacterium tuberculosis), thereby inhibiting the synthesis of mycolic ...
Paolo Ascenzi   +10 more
doaj   +1 more source

Antituberculosis Activity of Brotowali (Tinospora Crispa) Extract and Fractions Against Mycobacterium Tuberculosis Using Microplate Alamar Blue Assay Method [PDF]

open access: yes, 2017
Tuberculosis (TB), in which caused by pathogenic bacteria, Mycobacterium tuberculosis, has become the major causes of death among all of infectious diseases.
Irianti, T. (Tatang)   +5 more
core  

Assessing Eco‐Efficiency in Municipal Solid Waste Management Integrating Heterogeneity: A Latent Class Stochastic Frontier Analysis

open access: yesSustainable Development, EarlyView.
ABSTRACT The measurement of eco‐efficiency in the municipal solid waste (MSW) sector has garnered significant attention due to the substantial environmental impacts of unsustainable MSW management and the high operational costs associated with public service provision.
Ramon Sala‐Garrido   +2 more
wiley   +1 more source

Le lymphangiome circonscrit superficiel de la langue

open access: yesThe Pan African Medical Journal, 2018
A 40-year-old HIV-positive female presented with an erythematous macular eruption involving the malar and periorbital area, the forehead and neck of six weeks of duration (A).
Aicha Nassiri, Fatima Zahra Mernissi
doaj   +1 more source

Clofazimine, but Not Isoniazid or Rifampicin, Augments Platelet Activation in vitro

open access: yesFrontiers in Pharmacology, 2018
Although the inclusion of the cationic amphiphilic, anti-mycobacterial agent, clofazimine, in the chemotherapeutic regimens of patients with multidrug-resistant tuberculosis (TB) has contributed to improved outcomes, concerns remain about the cardiotoxic
Ronald Anderson   +9 more
doaj   +1 more source

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