Results 101 to 110 of about 46,386 (217)

Pathogenesis of Tuberculosis: Interplay Between Host Antituberculosis Immunity and Immune Evasion Strategies of Mycobacterium Tuberculosis

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang   +3 more
wiley   +1 more source

Patient‐Derived IgG Epitope Mapping of Bet v 1 Reveals Hypoallergenic Peptide Candidates for Safe and Next‐Generation Allergen Immunotherapy

open access: yesClinical &Experimental Allergy, Volume 56, Issue 8, Page 881-892, August 2026.
Mapping IgG epitopes of the major birch allergen Bet v 1 identified patient‐derived, hypoallergenic peptides that did not trigger degranulation. These findings support a novel, safer approach for peptide‐based allergen immunotherapy that leverages naturally induced IgG specificities from allergic individuals. ABSTRACT Background Allergen immunotherapy (
Lara Šošić   +10 more
wiley   +1 more source

Isoniazid and alopecia

open access: yesLung India, 2011
Somsri Wiwanitkit, Viroj Wiwanitkit
openaire   +3 more sources

Synthesis, characterization, and efficacy of antituberculosis isoniazid zinc aluminum-layered double hydroxide based nanocomposites

open access: yesInternational Journal of Nanomedicine, 2016
Bullo Saifullah,1 Mohamed Ezzat El Zowalaty,2,3 Palanisamy Arulselvan,3 Sharida Fakurazi,3,4 Thomas J Webster,5–7 Benjamin Mahler Geilich,5,6 Mohd Zobir Hussein1 1Materials Synthesis and Characterization Laboratory, Institute of Advanced ...
Saifullah B   +6 more
doaj  

Genetic Landscape of NAT2 in the Moroccan Population: Implications for Isoniazid Pharmacogenetics in Tuberculosis

open access: yesClinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT The NAT2 gene encodes N‐acetyltransferase 2, an enzyme critically involved in the biotransformation of numerous xenobiotics and aromatic amines, including isoniazid, a cornerstone drug in tuberculosis therapy. Genetic polymorphisms in NAT2 lead to variable acetylation rates, clinically categorized as poor, intermediate, or rapid metabolizer ...
Nada Benyahya   +6 more
wiley   +1 more source

Pellagra in Contemporary Clinical Practice (2000–2023): A Systematic Review

open access: yesInternational Journal of Dermatology, Volume 65, Issue 8, Page 1590-1599, August 2026.
This systematic review (2000–2023) of 1212 cases highlights pellagra's evolving etiology. While primary dietary deficiency (85%) persists in humanitarian crises, secondary forms from alcohol misuse (9.6%), isoniazid (14.3% of drug‐related cases), and malabsorption are rising.
Noureddine Litaiem   +2 more
wiley   +1 more source

Acetylator status-guided rapid reintroduction of isoniazid in tuberculosis patients with drug-induced hepatotoxicity. [PDF]

open access: yesJ Clin Tuberc Other Mycobact Dis
van Arkel C   +8 more
europepmc   +1 more source

Comparison of the Efficacy and Prognosis of Different Treatment Strategies for Spinal Tuberculosis Patients Undergoing Vertebral Augmentation Surgery by Mistake

open access: yesOrthopaedic Surgery, Volume 18, Issue 8, Page 1631-1640, August 2026.
Based on the clinical characteristics of patients with spinal tuberculosis after percutaneous vertebral augmentation, the corresponding diagnosis and treatment strategies were explored, and clinical data for the differential diagnosis of spinal tuberculosis were provided.
Xiong Xu   +10 more
wiley   +1 more source

Fluorinated Aminopiperidones as Non‐Glutarimide Thalidomide Analogs: Stereodivergent Synthesis and Validation

open access: yesChemMedChem, Volume 21, Issue 13, 14 July 2026.
Fluorinated aminopiperidones, designed as non‐glutarimide thalidomide analogs, were synthesized with full regio‐ and stereocontrol. The C*–CF3 used as carbonyl surrogate improved solubility and membrane interactions while abolishing cereblon binding.
Boštjan Adamlje   +11 more
wiley   +1 more source

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