Results 81 to 90 of about 64,783 (272)

Pediatric hereditary angioedema presenting as recurrent episodic abdominal pain and vomiting: Challenges in diagnosis and management

JPGN Reports, EarlyView.
Abstract Recurrent episodic abdominal pain and vomiting, with symptom‐free intervals between attacks, represent common and often challenging presentations in children, typically leading to extensive workups without a clear etiology, as standard diagnostic algorithms fail to include rare systemic conditions. We present the challenging diagnostic odyssey
Julio Nestor Busaniche, Jhoanna Valery Adauto Luizaga, Maria Soledad Arcucci, Claudio Alberto Salvador Parisi, Judith Cohen Sabban, Agustina Venditti, Valentina Riveros, Giancarlo Testa, Veronica Busoni   +8 more
wiley   +1 more source

Studies on isoniazid-induced hepatotoxicity in rabbits

, 1997
Approximately one-third of the world's population harbors the tuberculosis mycobacterium and it is estimated that tuberculosis kills over 2.5 million persons per year worldwide.
Sarich, Troy Casimir
core   +1 more source

Impact of isoniazid monoresistance on overall and vulnerable patient populations in Taiwan

Emerging Microbes and Infections
Isoniazid is an early bactericidal anti-tuberculosis (TB) agent and isoniazid mono-resistance TB is the most prevalent drug-resistant TB worldwide. Concerns exist regarding whether resistance to isoniazid would lead to delayed culture conversion and ...
Meng-Rui Lee, Li-Ta Keng, Ming-Chia Lee, Jin-Hua Chen, Chih-Hsin Lee, Jann-Yuan Wang   +5 more
doaj   +1 more source

Extensive transmission of isoniazid resistant M. tuberculosis and its association with increased multidrug-resistant TB in two rural counties of eastern China: A molecular epidemiological study

BMC Infectious Diseases, 2010
Background The aim of this study was to investigate the molecular characteristics of isoniazid resistant Mycobacterium tuberculosis (MTB), as well as its contribution to the dissemination of multi-drug resistant TB (MDR-TB) in rural areas of eastern ...
Wang Weibing, Jiang Weili, Hoffner Sven, Hu Yi, Xu Biao   +4 more
doaj   +1 more source

Theophylline-Isoniazid Interaction

, 1989
Drugs influencing hepatic microsomal enzyme systems, such as isoniazid, may affect the elimination pattern of theophylline. The case reported here refers to an adult female patient with a history of chronic asthma and intestinal tuberculosis who, during
Francesc Jané, Ricardo Cabezas, Josep Torrent, Iñaki Izquierdo   +3 more
core   +1 more source

Health risk assessment of heavy metal accumulation in fruits exposed to geothermal waters: a case study and global implications

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The present study investigated the potential health risks of heavy metals (HMs) in the fruits and leaves of mulberry and sour cherry trees exposed to water from Sivas geothermal basin (Turkey). RESULTS The target HMs were ranked according to their hazard index as: Cd < Pb < Zn < Cu < Ni < Mn < Cr. The total hazard index for mulberry
E Işıl Arslan Topal, Murat Topal, Erdal Çelik, Erdal Öbek   +3 more
wiley   +1 more source

The Impact Of NAT2 Polymorphism On Isoniazid Blood Levels And Liver Enzyme Elevation In Tuberculosis Patients In Surabaya, Indonesia [PDF]

Isoniazid is the most pharmacogenetically studied anti-tuberculosis (TB) drug. However, the NAT2 genotype profile and its impact on the treatment of TB patients in Surabaya, Indonesia, have not yet been discovered.
Sartika, Ratu Ayu Dewi, Wonggo, Dhammiko, Raharjo, Dian Natasya, Andrajati, Retnosari, Wahjudi, Mariana, Jonathan, Jonathan   +5 more
core   +2 more sources

Real World Use of the IL‐36 Receptor Antagonist Spesolimab: A Systematic Review and Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Spesolimab, an interleukin‐36 receptor antagonist, is approved for the treatment and prevention of generalised pustular psoriasis (GPP) flares. Its use has increasingly been reported in real‐world settings for both GPP and other inflammatory dermatoses.
Sophia A. Mense, Nicole Bavaro, Aashna Farishta, Jiaqi Chen, Raj Chovatiya   +4 more
wiley   +1 more source

Response of Patients Infected with Isoniazid-Resistant Tubercle Bacilli to Treatment with Isoniazid plus PAS Isoniazid Alone [PDF]

, 1961
This study from the Tuberculosis Chemotherapy Centre, Madras, compares patients infected with isoniazid-resistant tubercle bacilli (“R” patients) with those infected with isoniazid-sensitive tubercle bacilli (“S” patients) as regards, first, their ...
Devadatta, S, Ramakrishnan, C V, Selkon, J B, Bhatia, A L, Radhakrishna, S, Fox, Wallace, Mitchison, D A, Andrews, R H, Velu, S   +8 more
core   +1 more source

Isoniazid inhibits the heme-based reactivity of Mycobacterium tuberculosis truncated hemoglobin N.

PLoS ONE, 2013
Isoniazid represents a first-line anti-tuberculosis medication in prevention and treatment. This prodrug is activated by a mycobacterial catalase-peroxidase enzyme called KatG in Mycobacterium tuberculosis), thereby inhibiting the synthesis of mycolic ...
Paolo Ascenzi, Andrea Coletta, Yu Cao, Viviana Trezza, Loris Leboffe, Gabriella Fanali, Mauro Fasano, Alessandra Pesce, Chiara Ciaccio, Stefano Marini, Massimo Coletta   +10 more
doaj   +1 more source