Breakthrough Tuberculosis in a Large Cohort of People Living With HIV on Preventive Treatment. [PDF]
ABSTRACT Background Tuberculosis is a leading infectious cause of death globally and the main cause among those with HIV. TB preventive treatment (TPT) is key for preventing TB in people with HIV (PWH). Healthcare workers often worry about adverse effects of TPT regimens, including breakthrough TB–active TB during treatment.
Ruswa N, Günther G, Claassens M.
europepmc +2 more sources
Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636 [PDF]
The identification of potential new anti-tubercular cemotherapeutics is paramount due to the recent emergence of extensively drug-resistant strains of Mycobacterium tuberculosis (XDR-TB).Libraries of NAS-21 and NAS-91 analogues were synthesized and ...
Besra, Gurdyal S +2 more
core +2 more sources
Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
Isoniazid-induced flu-like syndrome: A rare side effect
Drug-induced flu-like syndrome is very rare. It is mainly produced by rifampicin. We report a case of pulmonary tuberculosis (PTB) that developed isoniazid-induced flu-like syndrome, but could be cured with a modified regimen replacing isoniazid with ...
Sudipta Pandit +4 more
doaj +1 more source
Lupus Vulgaris in a Maltese patient [PDF]
Introduction The incidence of cutaneous tuberculosis (TB) in the developed world has fallen, in parallel with the decline of other forms of TB. Nevertheless cases still occur and their diagnosis may be difficult.
Boffa, Michael J. +2 more
core
Tuberculous Pericarditis [PDF]
info:eu-repo/semantics ...
Faria, D, Freitas, A
core +1 more source
Antimicrobial effects of folk medicinal plants from the North of Iran against Mycobacterium tuberculosis [PDF]
Background: Medicinal plants have been used traditionally in Golestan province (north of Iran), against Mycobacterium tuberculosis or the clinical signs of tuberculosis (TB).
Davoodi, H. +6 more
core
Isoniazid-Induced Acute Psychosis in a Patient with Pleural Tuberculosis
Tuberculosis is one of the top 10 causes of death and the leading cause from a single infectious agent (above HIV/AIDS). Isoniazid is highly bactericidal against replicating tubercle bacilli and is a component of all antituberculous chemotherapeutic ...
Joana Gomes +3 more
doaj +1 more source
A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis. [PDF]
Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases.
Catanzaro, A +7 more
core +1 more source
Reprogrammable All‐Photonic Molecular Logic With Ln3+ Luminescent Hybrids in Solid State
Mario P. de‐Saralegui et al. report an Eu3⁺/Tb3⁺‐doped organic–inorganic hybrid material that enables multiple reprogrammable logic operations using only physical stimuli. Additionally, this solid‐state, all‐photonic platform represents the first example in the literature performing reversible Feynman logic operations, marking a major step toward ...
Mario P. de‐Saralegui +4 more
wiley +1 more source

