Results 91 to 100 of about 48,156 (193)
Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1101-1110, October 2026.NAT2 encodes arylamine N‐acetyltransferase 2, a key enzyme in the phase II metabolism of arylamines and arylhydrazines. NAT2 is highly polymorphic, resulting in variable distributions of rapid and poor metabolizers across global populations. Here, we detail the process undertaken by the Clinical Pharmacogenetics Implementation Consortium (CPIC) NAT2 ...
Bailey M. Tibben +10 more
wiley +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.ABSTRACT A series of 1‐(4‐Chorophenyl)‐3Aryl‐1‐H‐pyrazole‐4‐carbaldehyde derivatives were synthesized under the microwave irradiation (MW) technique. IR, 1H‐NMR, 13C‐NMR, and mass spectroscopic techniques were used to confirm the structure of the synthesized compounds.
Megha Kokane +6 more
wiley +1 more source
MicrobiologyOpen, Volume 15, Issue 5, October 2026.This bibliometric mapping of 1746 publications (2000–2025) charts molecular diagnostics for WHO priority bacterial pathogens across platforms, targets, and resistance markers. Conventional PCR/NAAT and whole‐genome sequencing emerge as complementary core platforms, and the field evolves from targeted pathogen detection into an AMR‐centered ...
Selahattin Ünlü
wiley +1 more source
Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management
MedComm, Volume 7, Issue 10, October 2026.A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley +1 more source
Should TNF inhibitors be avoided in psoriasis patients with latent tuberculosis?
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Fabià Torres‐Betato, Lluís Puig
wiley +1 more source
International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 1189-1200, October 2026.ABSTRACT Introduction Fully automated thrombin generation (TG) assays facilitate the transition from research to clinical application. We conducted a multicenter inter‐laboratory study using the ST Genesia analyzer to evaluate assay performance and establish reference intervals in healthy adults from Spain and Portugal.
Diego Velasco‐Rodríguez +21 more
wiley +1 more source
Journal of Applied Polymer Science, Volume 143, Issue 34, September 10, 2026.Kevlar is traditionally modeled as a rigid‐rod polymer, yet rheological behavior deviates from this assumption. The review introduces a novel “twist‐tie” entanglement theory for aramid polymer chains in the nematic liquid crystal state, providing a molecular explanation for deviations from rigid‐rod models. Understanding twist‐tie entanglement dynamics
Emma Egli +3 more
wiley +1 more source
Charting Morphotoxicity With Complementary Embryo Models
Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx +9 more
wiley +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, Volume 38, Issue 51, 11 September 2026.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Allosteric Inhibition of Polycomb Repressive Complex 2 by an EZH2‐Selective Small Molecule Inhibitor
Advanced Science, Volume 13, Issue 49, 3 September 2026.The study characterizes C36, a highly selective EZH2/PRC2 inhibitor that acts via a novel allosteric mechanism. Unlike previous inhibitors, C36 inhibits EZH2/PRC2 by disrupting the allosteric communication between EZH2 and EED in a SAM‐noncompetitive manner.
Ting Cao +11 more
wiley +1 more source