Results 91 to 100 of about 64,783 (272)

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Isoniazid

open access: yes, 2018
Inelastic Neutron Scattering spectrum of Isoniazid, C6H7N3O, measured on the TOSCA instrument. Isonicotinylhydrazide.
Ribeiro-Claro, P.J.A.
core   +1 more source

Integration of scRNA‐Seq and scATAC‐Seq Revealed the Role of lncRNA RP11‐661C8.2 by Promoting EMT in Clear Cell Renal Cell Carcinoma

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Long noncoding RNAs (lncRNAs) play an important role in tumor progression. However, most of the previously discovered lncRNAs that promote or inhibit tumor progression were derived from bulk RNA‐seq results. Data from single‐cell RNA sequencing (scRNA‐seq) and single‐cell assay for transposase‐accessible chromatin using sequencing (scATAC‐seq)
Jizhen Cen   +12 more
wiley   +1 more source

Clofazimine, but Not Isoniazid or Rifampicin, Augments Platelet Activation in vitro

open access: yesFrontiers in Pharmacology, 2018
Although the inclusion of the cationic amphiphilic, anti-mycobacterial agent, clofazimine, in the chemotherapeutic regimens of patients with multidrug-resistant tuberculosis (TB) has contributed to improved outcomes, concerns remain about the cardiotoxic
Ronald Anderson   +9 more
doaj   +1 more source

Prevalence and Associations of Abnormal Levels of Vitamin B6 in People with Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background In people with Parkinson's disease, abnormal levels of vitamin B6 may be associated with polyneuropathy and epileptic seizures, including medication‐refractory status epilepticus. Objectives To estimate the prevalence and explore associations of abnormal levels of vitamin B6 in people with Parkinson's disease.
Karlo J. Lizarraga   +7 more
wiley   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Bioactivity profiling of linear venom peptides from Italian small wood‐scorpion (Euscorpius italicus)

open access: yesPest Management Science, EarlyView.
Functional screening pipeline of venom peptides from Euscorpius italicus reveal their activity towards globally important pest insects, bacteria, and cells – providing insight on the potential and function of arachnid venom peptides. Abstract BACKGROUND Rising host‐expansion and the global spread of pest insects, confront agricultural sectors with ...
Maurice Pierry   +11 more
wiley   +1 more source

Clinical guideline highlights for the hospitalist: Updates on the treatment of drug‐susceptible and drug‐resistant tuberculosis

open access: yes
Journal of Hospital Medicine, EarlyView.
Allison Stickles   +3 more
wiley   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

White light emitting molecular logic gates

open access: yesSmart Molecules, EarlyView.
White light emitting smart molecules with Boolean logic computing ability are surveyed. Abstract White light emitting (WLE) materials are of considerable interest with commercial and societal applications in video displays and lighting devices. A characteristic property of WLE materials is the luminescence profile spanning from 380 to 700 nm.
Davide Benedetto Tiz   +2 more
wiley   +1 more source

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