Results 91 to 100 of about 87,478 (258)

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo   +5 more
wiley   +1 more source

Factors associated with isoniazid resistant tuberculosis among human immunodeficiency virus positive patients in Swaziland: a case-control study

open access: yesBMC Infectious Diseases, 2019
Background Isoniazid resistant tuberculosis is the most prevalent type of resistance in Swaziland and over two-thirds of the isoniazid resistant tuberculosis patients are tuberculosis and human immunodeficiency virus co-infected.
Nonhlanhla Christinah Dlamini   +2 more
doaj   +1 more source

Acneiform dermatoses [PDF]

open access: yes, 1998
Acneiform dermatoses are follicular eruptions. The initial lesion is inflammatory, usually a papule or pustule. Comedones are later secondary lesions, a sequel to encapsulation and healing of the primary abscess.
Jansen, Thomas, Plewig, G.
core   +1 more source

Assessing Eco‐Efficiency in Municipal Solid Waste Management Integrating Heterogeneity: A Latent Class Stochastic Frontier Analysis

open access: yesSustainable Development, EarlyView.
ABSTRACT The measurement of eco‐efficiency in the municipal solid waste (MSW) sector has garnered significant attention due to the substantial environmental impacts of unsustainable MSW management and the high operational costs associated with public service provision.
Ramon Sala‐Garrido   +2 more
wiley   +1 more source

Extensive transmission of isoniazid resistant M. tuberculosis and its association with increased multidrug-resistant TB in two rural counties of eastern China: A molecular epidemiological study

open access: yesBMC Infectious Diseases, 2010
Background The aim of this study was to investigate the molecular characteristics of isoniazid resistant Mycobacterium tuberculosis (MTB), as well as its contribution to the dissemination of multi-drug resistant TB (MDR-TB) in rural areas of eastern ...
Wang Weibing   +4 more
doaj   +1 more source

Post Penicillin Antibiotics: From acceptance to resistance? [PDF]

open access: yes, 2000
Edited transcript of a Witness Seminar held at the Wellcome Institute for the History of Medicine, in London, on 12 May 1998. First published by the Wellcome Trust, 2000. ©The Trustee of the Wellcome Trust, London, 2000.
Reynolds, LA, Tansey, EM
core  

Integrating multiple surveys using state–space models improves inference of population trends for Illinois furbearers

open access: yesWildlife Biology, EarlyView.
Long‐term population monitoring is fundamental to wildlife population management. Furbearer populations are often surveyed using multiple methods, but many estimates of their abundance, especially abundance indices, do not account for detection error, and lead to conflicting interpretations of population trends.
Lauren C. Scopel   +4 more
wiley   +1 more source

Isoniazid-induced flu-like syndrome: A rare side effect

open access: yesLung India, 2013
Drug-induced flu-like syndrome is very rare. It is mainly produced by rifampicin. We report a case of pulmonary tuberculosis (PTB) that developed isoniazid-induced flu-like syndrome, but could be cured with a modified regimen replacing isoniazid with ...
Sudipta Pandit   +4 more
doaj   +1 more source

Guselkumab Safety in Patients With Latent Tuberculosis: Analysis of 11 Studies in Psoriatic Disease

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Certain psoriatic disease treatments, including tumor necrosis factor‐α inhibitors (TNFi), increase tuberculosis (TB) risk. Testing for latent TB infection (LTBI) before initiating systemic therapy has been standard practice for psoriasis (PsO) patients; however, updated consensus states routine testing is not required before initiating ...
Luis Puig   +14 more
wiley   +1 more source

Lupus Vulgaris in a Maltese patient [PDF]

open access: yes, 2004
Introduction The incidence of cutaneous tuberculosis (TB) in the developed world has fallen, in parallel with the decline of other forms of TB. Nevertheless cases still occur and their diagnosis may be difficult.
Boffa, Michael J.   +2 more
core  

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