Results 171 to 180 of about 95,782 (307)

A Pediatric Case of Severe Atopic Dermatitis on Dupilumab Treatment and Pulmonary Tuberculosis

open access: yes
Pediatric Dermatology, EarlyView.
Maria Efenesia Baffa   +4 more
wiley   +1 more source

Integrating Genetic and Single‐Cell Genomic Data to Reveal Brain Cell‐Specific Regulation of Attention‐Deficit/Hyperactivity Disorder Risk in the Prefrontal Cortex

open access: yesBrain and Behavior, Volume 15, Issue 7, July 2025.
This study uncovers causal associations between specific brain cells in the prefrontal cortex and ADHD risk through single‐cell eQTL MR and Bayesian analyses, advancing our understanding of ADHD's neurobiology. Our findings highlight novel therapeutic targets, paving the way for new treatment strategies in ADHD management.
Jiawei Gui   +4 more
wiley   +1 more source

Delayed culture conversion predicts poor outcomes for isoniazid mono-resistant TB in Uganda: a retrospective cross-sectional study from 2017- 2022. [PDF]

open access: yesBMC Infect Dis
Kabugo J   +9 more
europepmc   +1 more source

SOME ASPECTS OF VIRULENCE OF ISONIAZID-RESISTANT TUBERCLE BACILLI

open access: bronze, 1955
KOOMI KANAI   +3 more
openalex   +2 more sources

Lupus Vulgaris on Face: A Case Report From Rural Nepal

open access: yesClinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Lupus vulgaris (LV), the most common form of cutaneous tuberculosis, results from Mycobacterium tuberculosis infection via hematogenous, lymphatic, or direct transmission in individuals with moderate immunity and high tuberculin sensitivity. It predominantly affects females, constituting 1%–2% of extrapulmonary tuberculosis cases, with facial ...
Sabin Kandel, Nikita Shah, Aayush Bist
wiley   +1 more source

Is Mycobacterial InhA a Suitable Target for Rational Drug Design?

open access: yesChemMedChem, Volume 20, Issue 13, July 1, 2025.
InhA is the target of isoniazid, a first‐line antituberculosis drug. Isoniazid is, in fact, a prodrug that needs to be activated. Researchers are trying to develop direct inhibitors of InhA. This includes the resolution of crystallographic structures. The Protein Data Bank contains over a hundred InhA structures.
Julien Rizet   +7 more
wiley   +1 more source

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