Results 171 to 180 of about 97,287 (310)

Molecular Encoding of Ischemic Stroke and its Resolution after Human Neural Stem Cell Therapy by Extracellular Vesicles

open access: yesMedComm, Volume 6, Issue 11, November 2025.
EVs can cross the blood–brain barrier and enter systemic circulation. By analyzing EV RNA cargoes before and after stroke, and following hNSC transplantation, our study shows that EV RNAs accurately reflect stroke pathology and provide insights into how hNSCs promote stroke recovery. These findings suggest that EV RNA profiles could serve as diagnostic
Chuheng Chang   +4 more
wiley   +1 more source

THE DETERMINATION OF ISONIAZID

open access: yesJournal of Pharmacy and Pharmacology, 1953
openaire   +3 more sources

Quantitative analysis of inhibitor‐induced assembly disruption in human UDP‐GlcNAc 2‐epimerase using mass photometry

open access: yesProtein Science, Volume 34, Issue 11, November 2025.
Abstract Uridine diphosphate N‐acetylglucosamine (UDP‐GlcNAc) 2‐epimerase (GNE)/N‐acetylmannosamine kinase is the rate‐limiting enzyme in sialic acid biosynthesis and a promising therapeutic target. We applied mass photometry (MP) to investigate GNE oligomerization and its modulation by three small‐molecule inhibitors (C5, C13, and C15).
Nico Boback   +4 more
wiley   +1 more source

MiR‐1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion

open access: yesEnvironmental Toxicology, Volume 40, Issue 11, Page 1249-1260, November 2025.
ABSTRACT MicroRNA‐1 (miR‐1) is a conserved microRNA that is highly expressed in skeletal and cardiac muscle tissues. Moreover, miR‐1 regulates genes and has critical roles in cell migration and invasion. Downregulation of miR‐1 has been found in many pathologies of numerous organs, including the lungs.
Maricica Pacurari   +2 more
wiley   +1 more source

Estimated costs of tuberculosis services in Brazil, 2023. [PDF]

open access: yesBMJ Open Respir Res
Jabbour E   +8 more
europepmc   +1 more source

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