Results 181 to 190 of about 64,783 (272)

Scaling-up tuberculosis preventive therapy to HIV-negative contacts of bacteriologically confirmed TB cases aged 5 years and above - Lessons from a tuberculosis preventive therapy surge activity in Zambia. [PDF]

PLOS Glob Public Health
Mwaba PB, Mwaba I, Maimbolwa MM, Chanda C, Mputu M, Lumbwe C, Zimba K, Chanda NK, Chimzizi R, Mubanga A, Muyoyeta M, Kagujje M.   +11 more
europepmc   +1 more source

A Multi‐Scale Computational Framework for Anti‐Persister Tuberculosis Drug Discovery

Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.
This review presents an integrated QSAR–scaffold design–docking–MD framework for discovering anti‐persister tuberculosis agents active in dormant granuloma‐like conditions. By targeting Mtb bioenergetics and prioritising dual NDH‐2/cytochrome bd oxidase inhibition, the workflow advances rational design of candidates with higher resistance barriers ...
Said Moshawih, Anguraj Moulishankar, Chee Yan Choo, Khang Wen Goh, Chrismawan Ardianto, Azam Che Idris, Long Chiau Ming   +6 more
wiley   +1 more source

Regimen-Specific Population Pharmacokinetics of Isoniazid with and Without Rifamycin: A Bayesian Modeling Analysis of 6H, 3HR, and 3H2P2 Regimens. [PDF]

Pharmaceutics
Li Z, Xiao X, Xu C, Liu Y, Gu L, Li X, Shen X, Hu Y.   +7 more
europepmc   +1 more source

Diagnosis and Management of Infectious Encephalitis in Adults: Guidelines From the European Academy of Neurology and European Society of Clinical Microbiology and Infectious Diseases

European Journal of Neurology, Volume 33, Issue 10, October 2026.
ABSTRACT Background Encephalitis is difficult to diagnose and manage, posing a challenge to clinicians. Since the last European guidelines were published in 2010, novel causes have emerged, diagnostic processes have evolved and treatments assessed which need to be reflected in updated guidelines.
Julia Granerod, Johann Sellner, Jean‐Paul Stahl, Sylviane Defres, Alexandra Mailles, Erich Schmutzhard, Elisabeth Aurelius, Thomas Whitfield, Luca Massacesi, Maarten J. Titulaer, Pille Taba, Benedict D. Michael, Tehmina Bharucha, Lance Turtle, Brendan Sargent, Arina Tamborska, Jonathan Cattrall, Yun Huang, Eva Maria Hodel, Suzannah Lant, Glynn Webb, Rajish S. K. Shil, Shalley Dhar, Diederik van de Beek, Marie Studahl, Matthijs C. Brouwer, Uta Meyding‐Lamade, Ava Easton, Bhagteshwar Singh, Tom Solomon   +29 more
wiley   +1 more source

Multicenter Interlaboratory Study of Thrombin Generation Assay in Healthy Adults Using the ST Genesia Analyzer With the STG‐ThromboScreen Reagent (With and Without Thrombomodulin)

International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 1189-1200, October 2026.
ABSTRACT Introduction Fully automated thrombin generation (TG) assays facilitate the transition from research to clinical application. We conducted a multicenter inter‐laboratory study using the ST Genesia analyzer to evaluate assay performance and establish reference intervals in healthy adults from Spain and Portugal.
Diego Velasco‐Rodríguez, María Marcos‐Jubilar, Inés Martínez‐Alfonzo, Laura Martos, Carlos Aguilar, Noelia Vilalta, Dolors Llobet, Ana Marco‐Rico, David Aragoneses, Pascual Marco, Luciana Ricca, David Ferreira, Sara Lopes, João Mariano‐Pego, Ángel Bernardo, Antonio Moscardó, Santiago Bonanad, Susana Gassiot, Isabel Gutiérrez‐Jomarrón, Jose Antonio Páramo, Pilar Llamas‐Sillero, Joan Carles Reverter   +21 more
wiley   +1 more source

Isoniazid-induced seronegative cutaneous lupus in a patient with lupus vulgaris. [PDF]

JAAD Case Rep
Shah S, Shrestha J, Bhusal M, Neupane D, Maharjan R, Baniya R.   +5 more
europepmc   +1 more source

Thrombomodulin Shapes Thrombo‐Inflammatory Interactions in Lupus Nephritis

Scandinavian Journal of Immunology, Volume 104, Issue 4, October 2026.
Lupus nephritis is characterized by a distinct thrombo‐inflammatory profile dominated by endothelial activation, with thrombomodulin emerging as the most consistent biological marker of renal involvement in systemic lupus erythematosus. ABSTRACT Lupus nephritis (LN) confers a disproportionate thrombotic risk in systemic lupus erythematosus (SLE) that ...
Mads Lamm Larsen, Lea Dich Pedersen, Annette Gudmann Hansen, Trine Korsgaard Hejlesen, Anders Bengtsson, Anne Voss, Ellen M. Hauge, Susan Due Kay, Bent Deleuran, Julie B. Larsen, Steffen Thiel, Anne Troldborg   +11 more
wiley   +1 more source

Acetylator status-guided rapid reintroduction of isoniazid in tuberculosis patients with drug-induced hepatotoxicity. [PDF]

J Clin Tuberc Other Mycobact Dis
van Arkel C, Stemkens R, Magis-Escurra C, Hoefsloot W, Carpaij N, van Ingen J, van Crevel R, van Laarhoven A, Aarnoutse R.   +8 more
europepmc   +1 more source

Factors influencing baseline electrocardiographic parameters in rats: A systematic review of experimental studies published from 1960 to the present

Physiological Reports, Volume 14, Issue 19, October 2026.
Abstract Experimental studies in rats use baseline or control values as a reference against which changes after experimental interventions are assessed. However, baseline or control ECG parameters may already be influenced by several factors before the experiment begins, complicating interpretation of the results.
Viktória Novotná, Soňa Grešová, Pavol Švorc   +2 more
wiley   +1 more source