Results 171 to 180 of about 64,783 (272)
Novel MA–St–CPMI terpolymers were synthesized by free‐radical terpolymerization. Positional isomerism significantly influenced their thermal stability, antioxidant efficiency, and antibacterial activity, highlighting their potential as multifunctional polymeric materials. ABSTRACT Novel multifunctional maleic anhydride–styrene–N‐carboxyphenylmaleimide (
Shahana Guliyeva +7 more
wiley +1 more source
ABSTRACT Characterizing dolutegravir penetration into the central nervous system is important for optimizing human immunodeficiency virus treatment outcomes, yet population‐specific pharmacokinetic data describing cerebrospinal fluid disposition and equilibration kinetics remain lacking.
Mohammed W. Ali +8 more
wiley +1 more source
Hepatic responses as potential biomarkers of idiosyncratic drug reaction risk. [PDF]
Liao J +4 more
europepmc +1 more source
ABSTRACT Tuberculosis (TB) treatment requires long‐term multidrug regimens where dosing, efficacy, and safety optimization remain challenging. This tutorial establishes an integrated, open‐source, modular framework connecting high‐throughput PBPK (HT‐PBPK) simulations, mechanistic PBPK models, pharmacodynamic endpoints, and safety predictions for anti ...
Marco Siccardi +9 more
wiley +1 more source
Implementation insights into bridging the gaps in isoniazid preventive therapy uptake in adults with HIV. [PDF]
Nevrekar N +9 more
europepmc +1 more source
ABSTRACT The measurement of eco‐efficiency in the municipal solid waste (MSW) sector has garnered significant attention due to the substantial environmental impacts of unsustainable MSW management and the high operational costs associated with public service provision.
Ramon Sala‐Garrido +2 more
wiley +1 more source
Management of <i>Mycobacterium bovis</i> Meningitis: The Case for Adjunctive Empirical Therapy. [PDF]
Birabaharan M, Cowell AN.
europepmc +1 more source
ABSTRACT Sampling environmental nucleic acids (eDNA and eRNA, collectively eNA) in aquatic systems facilitates the efficient exploration of the distribution of aquatic species. Since eRNA is inherently less stable than eDNA, eRNA may yield more spatiotemporally precise information about organisms, but this volatility also poses unique methodological ...
Elise D. Snyder +3 more
wiley +1 more source
Development and Preliminary Evaluation of RR-TB GoldDx and Hr-TB GoldDx: Rapid Visual RPA-Gold Nanoparticle Assays for Detecting Rifampicin- and Isoniazid-Resistance-Associated Mutations in <i>Mycobacterium tuberculosis</i>. [PDF]
Wattananandkul U +11 more
europepmc +1 more source
Anaerobic digester metagenomes revealed diverse resistance‐associated annotations and antibiotic target loci, highlighting their potential role in environmental AMR surveillance. The findings emphasise the need for cautious interpretation of resistome profiles and further host‐resolved analyses to determine the mobility and clinical relevance of ...
Olasunbo Aina Olasupo +12 more
wiley +1 more source

