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Pediatrics, 1987
To the Editor.— Notterman et al (Pediatrics 1986;77:850-852) reported about an 8-month-old infant who absorbed crushed isoniazid in applesauce poorly both during treatment for tuberculous meningitis and later in pharmacokinetic studies. A second child exhibited a less severe malabsorption.
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To the Editor.— Notterman et al (Pediatrics 1986;77:850-852) reported about an 8-month-old infant who absorbed crushed isoniazid in applesauce poorly both during treatment for tuberculous meningitis and later in pharmacokinetic studies. A second child exhibited a less severe malabsorption.
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Microdetermination of Isoniazids*
Journal of the American Pharmaceutical Association (Scientific ed.), 1953A method is detailed for the assay of isoniaaids. It depends upon the reduction of ferricyanide by the hydrazide in acid solution with subsequent estimation of the color produced with the aid of a photoelectric colorimeter. The method is simple, relatively raid, and requires apparatus commonly available in chemical, pharmaceutical, ancf clinical ...
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Transactions of the Royal Society of Tropical Medicine and Hygiene, 1955
Abstract 1. (1)Isoniazid was given alone in a 17- to 26-month trial in six patients, five with lepromatous leprosy, and one with tuberculoid leprosy, who had responded poorly to, or had had repeated lepra reactions from, the sulphone group of drugs. 2. (2) The dosage was never less than 3.9 mg/kg. body weight, and usually 8 to 9 mg/kg.
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Abstract 1. (1)Isoniazid was given alone in a 17- to 26-month trial in six patients, five with lepromatous leprosy, and one with tuberculoid leprosy, who had responded poorly to, or had had repeated lepra reactions from, the sulphone group of drugs. 2. (2) The dosage was never less than 3.9 mg/kg. body weight, and usually 8 to 9 mg/kg.
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