Results 21 to 30 of about 64,783 (272)

Rifampicin resistance in tuberculosis outbreak, London, England [PDF]

, 2005
Mycobacterium tuberculosis isolates cultured from 6 patients associated with an isoniazid-resistant M. tuberculosis outbreak acquired rifampicin resistance. The rpoB gene sequence showed that resistance was associated with rare mutations in each isolate.
Shorten, R J, McHugh, TD, Claxton, A P, Claxton, AP, Mary Jo Knobloch, Gillespie, S H, Claire Jenkins, Stephen H. Gillespie, Shorten, RJ, McHugh, T D, Edward A. Belongia, Richard E. Besser, Timothy D. McHugh, Robert J. Shorten, Burney A. Kieke, Carolyn Janette, Gillespie, SH, Jeffrey P. Davis, Jenkins, C, Alleyna P. Claxton, Gillespie, S H ; id_orcid   +20 more
core   +1 more source

Poor Compliance Makes Treatment of Latent Tuberculosis Infection Unsatisfactory

Journal of Primary Care & Community Health, 2012
Objectives: The recommended treatment for latent tuberculosis infection is isoniazid for 9 months, but this regimen has a low completion rate. The authors wanted to compare treatment with isoniazid and treatment with isoniazid and rifampin in the typical
Panupong Larppanichpoonphol, Satish Bagdure, Hoda Mojazi Amiri, Kenneth Nugent   +3 more
doaj   +1 more source

The protective effect of lycopene against oxidative kidney damage associated with combined use of isoniazid and rifampicin in rats

Brazilian Journal of Medical and Biological Research, 2021
It is known that the combined use of antibiotics, such as isoniazid and rifampicin, in the treatment of tuberculosis causes oxidative kidney damage. The aim of this study was to biochemically and histopathologically investigate the effect of lycopene on ...
F. Bedir, H. Kocaturk, O. Turangezli, E. Sener, S. Akyuz, F.B. Ozgeris, B. Dabanlioglu, H. Suleyman, D. Altuner, B. Suleyman   +9 more
doaj   +1 more source

Tuberculosis contact screening and isoniazid preventive therapy in a South Indian district: operational issues for programmatic consideration. [PDF]

, 2011
BACKGROUND: Under India's Revised National Tuberculosis Control Programme (RNTCP), all household contacts of sputum smear positive Pulmonary Tuberculosis (PTB) patients are screened for TB. In the absence of active TB disease, household contacts aged
Santosha Kelamane, Pothukuchi, Madhavi, Nagaraja, Sharath Burugina, Puneet Dewan, Dewan Puneet, Wares Fraser, Babu Sai, Babu, Sai, Nagaraja Sharath Burugina, null Shashidhar, Fraser Wares, Kelamane Santosha, Srinath Satyanarayana, Satyanarayana Srinath, Satyanarayana, Srinath, Madhavi Pothukuchi, Dewan, Puneet, Pothukuchi Madhavi, Kelamane, Santosha, Shashidhar, Sai Babu, Sharath Burugina Nagaraja, Wares, Fraser   +22 more
core   +1 more source

Phenotypic low-level isoniazid resistance as a marker to predict ethionamide resistance in Mycobacterium tuberculosis

International Journal of Mycobacteriology, 2017
Background: Tuberculosis is one of the most prevalent diseases in Pakistan. Pakistan has the highest burden of MDR-TB in the Eastern Mediterranean region. Ethionamide is an anti-tuberculous drug frequently used to treat MDR-TB.
Salima Qamar, Joveria Q Farooqi, Kausar Jabeen, Rumina Hasan   +3 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Safety of long-term isoniazid preventive therapy in children with HIV [PDF]

, 2014
Includes bibliographical references.Tuberculosis (TB) and HIV co-infection is association with significant morbidity and mortality, especially in young children.
Le Roux, Stanzi Maria
core   +1 more source

Protocol for a Case-Control Study to Investigate the Association of Pellagra With Isoniazid Exposure During Tuberculosis Preventive Treatment Scale-Up in Malawi

Frontiers in Public Health, 2020
Background: Pellagra is caused by niacin (vitamin B3) deficiency and manifested by a distinctive dermatitis. Isoniazid is critical for treating tuberculosis globally and is a component of most regimens to prevent tuberculosis. Isoniazid may contribute to
Scott A. Nabity, Kelvin Mponda, Steve Gutreuter, Diya Surie, Anne Williams, Anne Williams, Andrea J. Sharma, Elizabeth R. Schnaubelt, Rebekah E. Marshall, Hannah L. Kirking, Suzgo B. Zimba, Joram L. Sunguti, Laphiod Chisuwo, Mabvuto J. Chiwaula, Jesse F. Gregory, Robin da Silva, Michael Odo, Andreas Jahn, Thokozani Kalua, Rose Nyirenda, Belaineh Girma, James Mpunga, Nicole Buono, Alice Maida, Evelyn J. Kim, Laurence J. Gunde, Tigest F. Mekonnen, Andrew F. Auld, Adamson S. Muula, John E. Oeltmann   +29 more
doaj   +1 more source

Quantitative Analysis of Isoniazid and Its Four Primary Metabolites in Plasma of Tuberculosis Patients Using LC-MS/MS

Molecules, 2022
Isoniazid and its metabolites are potentially associated with hepatotoxicity and treatment outcomes in patients who receive antituberculosis (TB) therapy.
Nguyen Ky Anh, Pham My Tung, Min Jung Kim, Nguyen Phuoc Long, Yong-Soon Cho, Dong-Hyun Kim, Jae-Gook Shin   +6 more
doaj   +1 more source

Potential economic viability of two proposed rifapentine-based regimens for treatment of latent tuberculosis infection. [PDF]

PLoS ONE, 2011
Rifapentine-based regimens for treating latent tuberculosis infection (LTBI) are being considered for future clinical trials, but even if they prove effective, high drug costs may limit their economic viability.To inform clinical trial design by ...
David P Holland, Gillian D Sanders, Carol D Hamilton, Jason E Stout   +3 more
doaj   +1 more source