Protective effects of salep against isoniazid liver toxicity in wistar rats
Journal of Traditional and Complementary Medicine, 2018 Introduction: Isoniazid is a drug for treatment of tuberculosis. One of the main side effects of this drug is hepatotoxicity, which is a major cause of treatment interruption in tuberculosis.
Hossein Kargar Jahromi +4 more
doaj +1 more source
Isoniazid causes heart looping disorder in zebrafish embryos by the induction of oxidative stress
BMC Pharmacology and Toxicology, 2020 Background The cardiotoxicity of isoniazid on zebrafish embryos and its underlying mechanism is unclear. Methods Here, we exposed zebrafish embryos at 4 h post-fertilization to different levels of isoniazid and recorded the morphology and number of ...
Jie Ni +10 more
doaj +1 more source
PLA Microparticles for Pulmonary Delivery of AntiTB drugs: Biodistribution study [PDF]
, 2008 A dry powder inhalable (DPI) microparticles comprising anti-tuberculosis drugs incorporated in biodegradable polymers was developed for the treatment of pulmonary tuberculosis (P. Muttil _et al_. 2007).
Amit Misra +4 more
core +2 more sources
Negligible risk of inducing resistance in Mycobacterium tuberculosis with single-dose rifampicin as post-exposure prophylaxis for leprosy [PDF]
, 2016 Post-exposure prophylaxis (PEP) for leprosy is administered as one single dose of rifampicin (SDR) to the contacts of newly diagnosed leprosy patients. SDR reduces the risk of developing leprosy among contacts by around 60 % in the first 2-3 years after ...
Anthony, Richard +13 more
core +10 more sources
Mutiara Medika, 2013 Infeksi mikobakteria termasuk diantara infeksi yang paling sulit disembuhkan dari semua jenis infeksi bakteri. Mikobakteria yang patogen utamanya adalah Mycobacterium tuberculosis sebagai penyebab tuberkulosis (TB), yang mengakibatkan lebih banyak ...
Dwi Yuni Nur Hidayati +1 more
doaj +1 more source
The bactericidal activity of moxifloxacin in patients with pulmonary tuberculosis [PDF]
, 2003 Patients in whom acid-fast bacilli smear-positive pulmonary tuberculosis was newly diagnosed were randomized to receive 400 mg moxifloxacin, 300 mg isonaizid, or 600 mg rifampin daily for 5 days. Sixteen-hour overnight sputa collections were made for the
Bongard, E +7 more
core +1 more source
Effects of low incubation temperatures on the bactericidal activity of anti-tuberculosis drugs [PDF]
, 2011 OBJECTIVES: to explore the effect of low incubation temperatures and the consequent slowing of bacterial metabolism on the bactericidal action of anti-tuberculosis drugs against Mycobacterium tuberculosis.
Coleman, David +2 more
core +2 more sources
Initiation and completion rates of isoniazid preventive therapy among people living with HIV in Far-Western Region of Nepal : a retrospective cohort study [PDF]
, 2019 Objectives: Isoniazid preventive therapy (IPT), for people living with HIV (PLHIV) is the proven and recommended intervention to avert tuberculosis (TB).
Bhatta, Usha +5 more
core +1 more source
Inhalable spray-dried chondroitin sulphate microparticles: effect of different solvents on particle properties and drug activity [PDF]
, 2020 Spray-drying stands as one of the most used techniques to produce inhalable microparticles, but several parameters from both the process and the used materials affect the properties of the resulting microparticles.
Buttini, Francesca +6 more
core +1 more source
Poor Compliance Makes Treatment of Latent Tuberculosis Infection Unsatisfactory
Journal of Primary Care & Community Health, 2012 Objectives: The recommended treatment for latent tuberculosis infection is isoniazid for 9 months, but this regimen has a low completion rate. The authors wanted to compare treatment with isoniazid and treatment with isoniazid and rifampin in the typical
Panupong Larppanichpoonphol +3 more
doaj +1 more source