Results 11 to 20 of about 64,783 (272)

Isoniazid Preventive Therapy and Risk for Resistant Tuberculosis [PDF]

Emerging Infectious Diseases, 2006
In the context of tuberculosis (TB) resurgence, isoniazid preventive therapy (IPT) is increasingly promoted, but concerns about the risk for development of isoniazid-resistant tuberculosis may hinder its widespread implementation.
Maria Elvira Balcells, Sara L. Thomas, Peter Godfrey-Faussett, Alison D. Grant   +3 more
doaj   +2 more sources

Lansoprazole Ameliorates Isoniazid-Induced Liver Injury

Pharmaceuticals
Isoniazid is a first-line drug in antitubercular therapy. Isoniazid is one of the most commonly used drugs that can cause liver injury or acute liver failure, leading to death or emergency liver transplantation.
Eri Wakai, Takashi Shiromizu, Shota Otaki, Junko Koiwa, Satoshi Tamaru, Yuhei Nishimura   +5 more
doaj   +2 more sources

Research Progress of isoniazid electrochemical sensors

Electrochemistry Communications
This paper reviews the research progress of isoniazid electrochemical sensors in recent years. As an important anti-tuberculosis drug, the rapid and sensitive detection of isoniazid is of great significance for clinical treatment and drug quality control.
Huanyu Che, Gaihua He, Xuekun Liu, Xin Guo, Chang Lei, Ye Liao   +5 more
doaj   +2 more sources

Severe isoniazid related sideroblastic anemia [PDF]

Hematology Reports, 2011
Isoniazid induced sideroblastic anemia is a rare event. We report case of a 45 year old Caucasian women with development of severe anaemia 4 month after introduction of Isoniazid as part of Tuberculosis treatment.
Rein Jan Piso, Kveti Kriz, Marie-Claire Desax   +2 more
doaj   +2 more sources

Isoniazid-Induced Acute Psychosis in a Patient with Pleural Tuberculosis

Case Reports in Psychiatry, 2019
Tuberculosis is one of the top 10 causes of death and the leading cause from a single infectious agent (above HIV/AIDS). Isoniazid is highly bactericidal against replicating tubercle bacilli and is a component of all antituberculous chemotherapeutic ...
Joana Gomes, Diana Durães, André Sousa, Hugo Afonso   +3 more
doaj   +2 more sources

Adverse events with isoniazid preventive therapy: experience from a large trial. [PDF]

, 2010
OBJECTIVES: We describe isoniazid-related adverse events in Thibela TB, a cluster-randomized study of community-wide isoniazid preventive therapy (IPT) among gold miners in South Africa, where HIV prevalence is estimated at 30%.
Clare L van Halsema, Grant, Alison D, van Halsema, Clare L, Alison D Grant, Churchyard, Gavin J, Gavin J Churchyard, Luttig, Mariëtha M, Fielding, Katherine L, Kathryn T Mngadi, Mngadi, Kathryn T, Katherine L Fielding, Mariëtha M Luttig   +11 more
core   +1 more source

Tuberculosis outcomes and drug susceptibility in individuals exposed to isoniazid preventive therapy in a high HIV prevalence setting. [PDF]

, 2010
OBJECTIVE: Despite World Health Organization recommendations, concerns about promoting resistance have impeded implementation of isoniazid preventive therapy (IPT) for tuberculosis (TB). We describe characteristics of TB in individuals previously exposed
Grant, Alison D, van Halsema, Clare L, Churchyard, Gavin J, Fielding, Katherine L, Chihota, Violet N, Lewis, James JC, Russell, Elizabeth C   +6 more
core   +1 more source

Isoniazid causes heart looping disorder in zebrafish embryos by the induction of oxidative stress

BMC Pharmacology and Toxicology, 2020
Background The cardiotoxicity of isoniazid on zebrafish embryos and its underlying mechanism is unclear. Methods Here, we exposed zebrafish embryos at 4 h post-fertilization to different levels of isoniazid and recorded the morphology and number of ...
Jie Ni, Hongye Wang, Xiyi Wei, Kangjie Shen, Yeqin Sha, Yuxiang Dong, Yimei Shu, Xiaojie Wan, Jingwen Cheng, Fang Wang, Yihai Liu   +10 more
doaj   +1 more source

Implementation of tuberculosis intensive case finding, isoniazid preventive therapy, and infection control ("Three I's") and HIV-tuberculosis service integration in lower income countries [PDF]

, 2016
World Health Organization advocates for integration of HIV-tuberculosis (TB) services and recommends intensive case finding (ICF), isoniazid preventive therapy (IPT), and infection control ("Three I's") for TB prevention and control among persons living ...
M Katherine Charles, Barbara Castelnuovo (10700), Nguyen Thi Dung, Divine Avit-Edi, Cortés Moncada, Claudia, IeDEA, Ballif, Marie, Nakigozi, Gertrude, Marie Ballif, Durier, Nicolas, Dusingize, Jean Claude, Charles, M Katherine, Nguyen, Thi Dung, Wester, C William, ,, Meridith Blevins, Dung, Nguyen Thi, Cortes, Claudia P, Cortes, Claudia P., Fenner, Lukas, C William Wester, Wester, C. William, Jean Claude Dusingize (473718), Divine Avit-Edi (2609464), Claudia P. Cortes (473719), Mary Lou Lindegren (2609461), Lindegren, Mary Lou, Gertrude Nakigozi, Charles, M. Katherine, Gertrude Nakigozi (247948), C. William Wester (250717), Timothy R. Sterling (148936), Lukas Fenner, Marie Ballif (368655), Blevins, Meridith, Nicolas Durier (326615), Jean Claude Dusingize, Claudia P Cortes, Avit-Edi, Divine, Sterling, Timothy R., Nguyen Thi Dung (245054), Nicolas Durier, Castelnuovo, Barbara, Timothy R Sterling, International epidemiology Databases to Evaluate AIDS (IeDEA) Collaboration, Mary Lou Lindegren, Barbara Castelnuovo, Lukas Fenner (149822), Sterling, Timothy R, Meridith Blevins (291088), M. Katherine Charles (2609458), Sterling TR, Ballif M, Castelnuovo B, Fenner L, Blevins M, Charles MK, Avit-Edi D, Durier N, Cortes CP, Nakigozi G, Wester CW, Lindegren ML, Dung NT, Dusingize JC   +64 more
core   +3 more sources

A Radioimmunoassay for Isoniazid

Clinical Chemistry, 1975
Abstract A sensitive radioimmunoassay is described, for measuring isoniazid in therapeutic and subtherapeutic concentrations. This radioimmunoassay was used in an exploratory clinical study to measure, as a function of time, the concentration of this drug in plasma of patients receiving isoniazid therapy.
R, Schwenk, K, Kelly, K S, Tse, A H, Sehon   +3 more
openaire   +2 more sources