Results 51 to 60 of about 40,846 (271)

Label‐Free and Immobilization‐Free Protein‐Binding Assays by Ultraviolet Transient Absorption Microscopy

open access: yesAdvanced Science, EarlyView.
A femtosecond UV pump–probe microscope resolves binding‐induced changes in protein excited‐state dynamics and converts these intrinsic contrasts into an equilibrium affinity readout. By probing tryptophan responses directly in solution, the approach enables quantitative determination of dissociation constants without labeling or immobilization ...
Jianghao Shen   +5 more
wiley   +1 more source

Perfluoro effect in the photoelectron spectra of quinoline and isoquinoline [PDF]

open access: yes, 1972
The high-resolution He 584Aophotoelectron spectra of heptafluoroquinoline and heptafluoroisoquinoline are compared with those of the parent compounds. Shifts in π ionisation potentials, due to the fluorine substitution, can be described with an inductive
Ham, D.M.W. van den, Meer, D. van der
core   +3 more sources

Crystal structures of 2-methoxyisoindoline-1,3-dione, 1,3-dioxoisoindolin-2-yl methyl carbonate and 1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-2-yl methyl carbonate: three anticonvulsant compounds

open access: yesActa Crystallographica Section E, 2014
The title compounds, C9H7NO3, (1), C10H7NO5, (2), and C14H9NO5, (3), are three potentially anticonvulsant compounds. Compounds (1) and (2) are isoindoline derivatives and (3) is an isoquinoline derivative.
Fortune Ezemobi   +4 more
doaj   +1 more source

Alternative final steps in berberine biosynthesis in Coptis japonica cell cultures [PDF]

open access: yes, 1988
In Coptis japonica cell cultures an alternative pathway has been discovered which leads from (S)-tetrahydrocolumbamine via (S)-canadine to berberine. The two enzymes involved have been partially purified.
Galneder, E.   +4 more
core   +1 more source

Crystal structure and Hirshfeld surface analysis of 4′-(2-chlorophenyl)-1′-methyl-3′′-phenyl-7′′,8′′-dihydro-5′′H-dispiro[indoline-3,2′-pyrrolidine-3′,6′′-isoquinoline]-2,5′′-dione

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2018
In the title dispiro compound, C32H26ClN3O2, the cyclohexanone ring of the isoquinoline unit has a distorted envelope conformation, with the methylene C atom adjacent to the spiro C atom as the flap.
R. Vishnupriya   +5 more
doaj   +1 more source

Selenomethionine Regulates the Arachidonic Acid Metabolism‐Ferroptosis‐Inflammation Axis to Ameliorate Colitis

open access: yesAnimal Research and One Health, EarlyView.
Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian   +8 more
wiley   +1 more source

Highly efficient electrochemiluminescence of quinoline and isoquinoline in aqueous solution

open access: yesElectrochemistry Communications, 2019
This paper reports for the first time the strong cathodic electrochemiluminescence (ECL) behavior of quinoline, isoquinoline and their derivatives in aqueous solution with K2S2O8 as coreactant. The effects of K2S2O8 concentration, pH and scan rate on the
Xiangxiang Qin   +3 more
doaj   +1 more source

Synthesis and structure - Activity relationship study of potent cytotoxic analogues of the marine alkaloid Lamellarin D [PDF]

open access: yes, 2014
The marine alkaloid, Lamellarin D (Lam-D), has shown potent cytotoxicity in numerous cancer cell lines, and was recently identified as a potent topoisomerase I inhibitor.
Albericio Palomera, Fernando   +6 more
core   +2 more sources

Research Progress of Polyoxometalate‐Integrated Frameworks: Syntheses, Properties, and Applications

open access: yesChemistryEurope, EarlyView.
This review systematically summarizes the integration of polyoxometalates with covalent organic frameworks, metal‐organic frameworks, hydrogen‐bonded organic frameworks, and emerging porous hosts. It highlights synergistic effects, synthesis strategies, and applications in catalysis, energy storage, sensing, and biomedicine, while addressing current ...
De‐Yin Wang   +6 more
wiley   +1 more source

Accessing Molecular Complexity from Methane and Other Gaseous Alkanes via Photocatalytic Cascade Cyclization

open access: yesAngewandte Chemie, Volume 138, Issue 5, 28 January 2026.
An iron‐catalyzed protocol for the cascade cyclization of N‐aryl and N‐benzoyl acrylamides promoted by methane and other gaseous alkanes is reported. The current protocol provides an efficient platform for the conversion of feedstock gaseous alkanes into complex and medicinally relevant N‐heterocycles.
Akshay M. Nair   +3 more
wiley   +2 more sources

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