Results 51 to 60 of about 34,528 (221)
Intramolecular cyclization of b,b-difluorostyrenes bearing an iminomethyl or a diazenyl group at the ortho position: synthesis of 3-fluorinated isoquinoline and cinnoline derivatives [PDF]
, 2007 journal ...
ICHIKAWA Junji +4 more
core +1 more source
ChemistryOpen, EarlyView.Unprotected glycosyl pyridinium salts may be accessed in a single step from the corresponding unprotected sugar in aqueous solution. Whilst meta‐ and para‐substitution is well tolerated, ortho substitution of the N‐heterocycle inhibits product formation. Electrochemical studies revealed reduction potentials in the range of −0.9 to −1.4 V.
Daniel Chong +2 more
wiley +1 more source
ChemistryOpen, EarlyView.The photoinduced decarboxylative radical addition of aryl carboxylic acids, including heteroaromatic carboxylic acids, to electron‐deficient alkenes is achieved in a two‐molecule photoredox system using a combination of biphenyl and 9,10‐dicyanoanthracene without heating or base.
Daisuke Suzuki +5 more
wiley +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Deregulation of the mechanistic target of the rapamycin (mTOR) pathway plays an important role in cancer genesis and progression, making it an attractive target for cancer treatment. Disrupting the mTOR pathway contributes to uncontrolled cell growth, increased proliferation, and enhanced cell survival, all of which are hallmarks of cancer ...
Sonali Khanal +9 more
wiley +1 more source
Synthesis and structure - Activity relationship study of potent cytotoxic analogues of the marine alkaloid Lamellarin D [PDF]
, 2014 The marine alkaloid, Lamellarin D (Lam-D), has shown potent cytotoxicity in numerous cancer cell lines, and was recently identified as a potent topoisomerase I inhibitor.
Albericio Palomera, Fernando +6 more
core +2 more sources
The Chemical Record, EarlyView.The stabilization of precursors substituted with 2‐, 1‐naphthol via partially aromatic ortho‐quinone methide intermediate was tested with different cyclic imines in [4+2] cycloaddition.8‐Hydroxyquinoline as a formal 1‐naphthol analogue in Mannich reaction was tested.The formed Mannich bases substituted with 2‐ and 1‐naphthol, 5‐chloro‐8 ...
Dóra Hegedűs +3 more
wiley +1 more source
Influence of Quaternary Benzophenantridine and Protopine Alkaloids on Growth Performance, Dietary Energy, Carcass Traits, Visceral Mass, and Rumen Health in Finishing Ewes under Conditions of Severe Temperature-humidity Index. [PDF]
, 2015 Twenty Pelibuey×Katahdin ewes (35±2.3 kg) were used to determine the effects of the consumption of standardized plant extract containing a mixture of quaternary benzophenanthridine alkaloids and protopine alkaloids (QBA+PA) on growth performance, dietary
Aguilar-Hernández, A +9 more
core +2 more sources
Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications
Cell Proliferation, EarlyView.Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su +5 more
wiley +1 more source
The Synthesis of Azaperylene-9,10-dicarboximides [PDF]
, 2010 The syntheses of two azaperylene 9,10-dicarboximides are presented. 1-Aza- and 1,6-diazaperylene 9,10-dicarboximides containing a 2,6-diisopropylphenyl substituent at the N-imide position were synthesized in two steps starting from naphthalene and ...
Andrew, Trisha Lionel +2 more
core +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Tryptophan decarboxylase (TDC), the rate‐limiting enzyme of tryptophan metabolism in plants, is essential for the production of a series of bioactive molecules, such as serotonin, melatonin and the plant hormone indole‐3‐acetic acid and therefore plays crucial roles in various aspects of growth and development.
Haili Zhang +13 more
wiley +1 more source