Research Progress on Neuroprotective Effects of Isoquinoline Alkaloids [PDF]
Molecules, 2023 Neuronal injury and apoptosis are important causes of the occurrence and development of many neurodegenerative diseases, such as cerebral ischemia, Alzheimer’s disease, and Parkinson’s disease. Although the detailed mechanism of some diseases is unknown,
Jinhua Li +6 more
doaj +2 more sources
Can Isoquinoline Alkaloids Affect Platelet Aggregation in Whole Human Blood? [PDF]
Toxins, 2022 Isoquinoline alkaloids have multiple biological activities, which might be associated with positive pharmacological effects as well as negative adverse reactions.
Mst Shamima Parvin +8 more
doaj +2 more sources
Interaction of isoquinoline alkaloids with pyrimidine motif triplex DNA by mass spectrometry and spectroscopies reveals diverse mechanisms [PDF]
Heliyon, 2023 Isoquinoline alkaloids represent an important class of molecules due to their broad range of pharmacology and clinical utility. Prospective development and use of these alkaloids as effective anticancer agents have elicited great interest. In this study,
Zhaoyang Xie +8 more
doaj +2 more sources
Isoquinoline alkaloids isolated from Glaucium corniculatum var. corniculatum and Glaucium grandiflorum subsp. refractum var. torquatum with bioactivity studies [PDF]
Pharmaceutical Biology, 2023 Context The genus Glaucium Mill., one of the important Papaveraceae family plants, is rich in isoquinoline alkaloids and distributed worldwide.Objective Isolation and identification of bioactive alkaloids from Glaucium grandiflorum Boiss. & Huet.
Tuba Kusman Saygi +5 more
doaj +2 more sources
Effects of isoquinoline alkaloids as an alternative to antibiotic on oxidative stress, inflammatory status, and cecal microbiome of broilers under high stocking density [PDF]
Poultry ScienceThis study investigated the effect of isoquinoline alkaloids as an alternative to bacitracin on growth performance, oxidative stress, inflammatory status, and ceca microbiome of broilers raised under high stocking density (HSD).
Kittisak Insawake +7 more
doaj +2 more sources
Protoberberine Isoquinoline Alkaloids from Arcangelisia gusanlung [PDF]
Molecules, 2014 HPLC-DAD-directed isolation and purification of the methanol extract of stems of Arcangelisia gusanlung H. S. Lo. led to the isolation of a new protoberberine alkaloid, gusanlung E (1), along with fourteen known derivatives 2–15, seven of which were ...
Ling-Ling Yu +5 more
doaj +3 more sources
Chelidonium majus L.: A Current Perspective on Isoquinoline Alkaloids, Emerging Phytochemicals, Alkaloid Biosynthesis, and Biological Activities [PDF]
PlantsPhytochemistry serves as a vital bridge between traditional medicinal knowledge and modern scientific research, with important implications for pharmaceutical and industrial applications.
Ramona Romanu +6 more
doaj +2 more sources
Effect of magnetization on antibacterial, lipid-lowering and antioxidant activities of isoquinoline alkaloids [PDF]
Scientific ReportsThe magnetization strategy of isoquinoline alkaloids has been successfully used in the extraction and isolation, but the effect of the magnetization on biological activities of those alkaloids still deserves further investigation.
Xueting Feng +4 more
doaj +2 more sources
Inhibitory Activity of Quaternary Isoquinoline Alkaloids on Soluble Epoxide Hydrolase [PDF]
Current Issues in Molecular Biology, 2022 The quaternary isoquinoline alkaloids of palmatine (1), berberine (2), and jatrorrhizine (3) were evaluated in terms of their ability to inhibit soluble epoxide hydrolase (sEH). They had similar inhibitory activities, with IC50 values of 29.6 ± 0.5, 33.4
Jang Hoon Kim +8 more
doaj +2 more sources
Interactions of Isoquinoline Alkaloids with Transition Metals Iron and Copper [PDF]
Molecules, 2022 Data on alkaloid interactions with the physiologically important transition metals, iron and copper, are mostly lacking in the literature. However, these interactions can have important consequences in the treatment of both Alzheimer’s disease and cancer.
Mst Shamima Parvin +6 more
doaj +2 more sources