Results 21 to 30 of about 5,376 (171)

LC-MS/MS BASED DEREPLICATION OF ISOQUINOLINE-DERIVED ALKALOIDS FROM THE TRUNK BARK OF Unonopsis rufescens (Baill.) R.E.Fr. (Annonaceae) [PDF]

Química Nova
Mass spectrometry-based approaches constitute the primary strategy for the dereplication of isoquinoline-derived alkaloids, which are widely distributed in various genera of the Annonaceae family.
Lucas Antônio F. de Almeida, Felipe Moura A. da Silva, Bruna Ribeiro de Lima, Aline Bastos B. de Sousa, Francinaldo A. da Silva Filho, Brenda R. C. Leocadio, Ana Paula A. Castro, Rebeca dos S. França, Hector H. F. Koolen, Afonso D. L. de Souza, Maria Lúcia B. Pinheiro   +10 more
doaj   +1 more source

Alkaloids Induce Programmed Cell Death in Bloodstream Forms of Trypanosomes (Trypanosoma b. brucei)

Molecules, 2008
The potential induction of a programmed cell death (PCD) in Trypanosoma b. brucei by 55 alkaloids of the quinoline, quinolizidine, isoquinoline, indole, terpene, tropane, steroid, and piperidine type was studied by measuring DNA fragmentation and changes
Michael Wink, Vera Rosenkranz
doaj   +1 more source

In Vitro Study of the Metabolic Characteristics of Eight Isoquinoline Alkaloids from Natural Plants in Rat Gut Microbiota

Molecules, 2017
Gut microbiota is populated with an immense number of microorganisms, which can be regulated by dietary components and drugs to markedly affect the nutritional and health status of the host. Eight medicinal isoquinoline alkaloids from natural plants were
Chi-Yu He, Jie Fu, Jia-Wen Shou, Zhen-Xiong Zhao, Long Ren, Yan Wang, Jian-Dong Jiang   +6 more
doaj   +1 more source

The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway

Chinese Medicine, 2023
Highlights The total extract of Corydalis hendersonii Hemsl. (CH) and the rich alkaloids fraction (RAF) of CH showed significant cardioprotective effect on mice following acute myocardial infarction.
Fuxing Ge, Xiaoli Gao, Xiaochun Zhou, Junjun Li, Xiaojing Ma, Meiwen Huang, Sana Wuken, Pengfei Tu, Chao An, Xingyun Chai   +9 more
doaj   +1 more source

Isoquinoline Alkaloids from Corydalis taliensis

Zeitschrift für Naturforschung B, 2007
Corydalis taliensis Franch is a perennial herb used for treatment of rheumatic arthritis, toothache, and hepatitis. The chemical investigation of this plant resulted in the isolation of a new compound, named taliensineside (1). Its structure was identified on the basis of spectral evidence.
Ying‐Rui Wu, You‐Xing Zhao, Yu‐Qing Liu, Jun Zhou   +3 more
openaire   +1 more source

Isoquinoline Alkaloids Isolated from Corydalis yanhusuo and Their Binding Affinities at the Dopamine D1 Receptor

Molecules, 2008
Bioactivity-guided fractionation of Corydalis yanhusuo has resulted in the isolation of eight known isoquinoline alkaloids - tetrahydropalmatine, isocorypalmine, stylopine, corydaline, columbamine, coptisin, 13-methylpalmatine, and dehydrocorybulbine ...
David Y. W. Lee, Lee-Yuan Liu-Chen, Bryan L. Roth, Niels H. Jensen, Wei Xu, Zhong-Ze Ma   +5 more
doaj   +1 more source

Hypecoum spp.—Chemistry and Biological Activity of Alkaloids

Diversity, 2023
Genus Hypecoum Tourn. ex L. belongs to the poppy family Papaveraceae and comprises about 19 species occurring in Europe, Northern Africa and Asia.
Nadezhda Kostova, Tsvetelina Doncheva
doaj   +1 more source

Isoquinoline Alkaloids and Indole Alkaloids Attenuate Aortic Atherosclerosis in Apolipoprotein E Deficient Mice: A Systematic Review and Meta-Analysis

Frontiers in Pharmacology, 2018
Background: Several studies have attempted to relate the bioactive alkaloid with atherosclerotic cardiovascular diseases prevention in animal models, providing inconsistent results.
Yibing Zhang, Yibing Zhang, Min Li, Xiangjun Li, Tong Zhang, Meng Qin, Liqun Ren   +6 more
doaj   +1 more source

Research on synthesis of microwave‐assisted heterocyclic compounds with eco‐friendly solvents and transition metals via C–H activation

Bulletin of the Korean Chemical Society, EarlyView.
This review summarizes microwave‐assisted transition‐metal catalysis for constructing N‐ and O‐heterocycles, highlighting rapid C–H and pre‐activated C–X activation, improved selectivity, and green synthetic efficiency. Abstract Microwave‐assisted organic synthesis provides a rapid and sustainable platform for synthesizing various heterocycles ...
Woo‐Jin Park, Ye Ri Han, Hyejeong Lee
wiley   +1 more source

Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis

Molecules, 2009
The stem bark of Phoebe grandis afforded one new oxoproaporphine; (–)-grandine A (1), along with six known isoquinoline alkaloids: (–)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that
Khalijah Awang, Marc Litaudon, Noel F. Thomas, A. Hamid A. Hadi, Ahmad Nazif Aziz, Mat Ropi Mukhtar   +5 more
doaj   +1 more source