Results 51 to 60 of about 5,376 (171)

Isolation and X-ray Crystal Structure of Tetrahydroisoquinoline Alkaloids from Calycotome Villosa Subsp. intermedias

Molecules, 2004
Two tetrahydroisoquinoline alkaloids were extracted from the alkaloid fraction of a methanol extract of the seeds of Calycotome Villosa Subsp. intermedia.
Mohammed Lachkar, Brahim El Bali, Michael Bolte, Rachid El Alami, Mohamed Bouktaib, Ibtissam Messouri, Ali El Antri   +6 more
doaj   +1 more source

Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie, Abdelghafar Abu‐Elsaoud   +1 more
wiley   +1 more source

Emergence, Challenges, and Opportunities for Chiral Nanocellulose Assemblies in Tissue Engineering and Wound Healing

Small Structures, Volume 7, Issue 3, March 2026.
This review explores chiral nanomaterials for tissue engineering and wound healing, specifically focusing on the potential of nanocellulose. The inherent chirality of nanocelluloses and their assemblies enables the creation of biomimetic scaffolds with unique biological interactions. Chiral nematic self‐assembly of cellulose nanocrystals, in particular,
Mahboubeh Nabavinia, Hossein Khanjanzadeh, Asier R. Muguruza, Anna Roig, Erlantz Lizundia, Justin O. Zoppe   +5 more
wiley   +1 more source

Antibacterial, Antifungal and Cytotoxic Isoquinoline Alkaloids from Litsea cubeba

Molecules, 2012
Five novel isoquinoline alkaloids (+)-N-(methoxylcarbonyl)-N-nordicentrin (1), (+)-N-(methoxylcarbonyl)-N-norpredicentrine (2), (+)-N-(methoxylcarbonyl)-N-norbulbodione (3), and (+)-N-(methoxylcarbonyl)-N-norisocorydione (4), and (+)-8 ...
Guo-Bing Shi, Qing-Chun Zhao, Jin-Feng Hu, Wen-Wen Lv, Wei Zhang   +4 more
doaj   +1 more source

Transposable Element‐Mediated Structural Variation Drives Flower Colour Diversification in Camellia

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1725-1739, March 2026.
ABSTRACT The role of transposable elements (TEs) in genome evolution and phenotypic diversification in Camellia remains poorly understood. Here, we present an integrated analysis of genome resequencing data from 237 Camellia accessions and 11 de novo genome assemblies representing all major floral colour types.
Menglong Fan, Hong Jiang, Yuxiao Qu, Ying Zhang, Xinlei Li, Yan Wang   +5 more
wiley   +1 more source

Isoquinoline alkaloids from Asimina triloba

Natural Product Research, 2018
A new aporphine glycoside, (-)-anolobine-9-O-β-D-glucopyranoside was isolated from the twigs of pawpaw (Asimina triloba) along with 7 known alkaloids including five aporphine alkaloids (anolobine, nornuciferine, norushinsunine, liriodenine, and lysicamine), a proaporhine alkaloid (stepharine), and a tetrahydrobenzylisoquinoline alkaloid (coclaurine ...
Taghreed A, Majrashi, Fazila, Zulfiqar, Amar G, Chittiboyina, Zulfiqar, Ali, Ikhlas A, Khan   +4 more
openaire   +2 more sources

Open data phylometabolomics reveals turnover‐dominated chemical divergence and clade‐specific physicochemical regimes across angiosperms

The Plant Journal, Volume 125, Issue 6, March 2026.
Significance Statement Using an open, reproducible phylometabolomics pipeline (LOTUS + standardized taxonomy; ~77 000 occurrences), we show that angiosperm chemodiversity diverges primarily by turnover (replacement), not nested accumulation. Despite this dynamism, major clades occupy distinct physicochemical regimes, revealing conserved constraints ...
Carlos Alexandre Carollo, Amanda Galdi Boaretto, Mariana Calarge Nocetti, Aline Regina Hellmann Carollo, Flávio Macedo Alves   +4 more
wiley   +1 more source

Extracts from Traditional Chinese Medicinal Plants Inhibit Acetylcholinesterase, a Known Alzheimer’s Disease Target

Molecules, 2016
Inhibition of acetylcholinesterase (AChE) is a common treatment for early stages of the most general form of dementia, Alzheimer’s Disease (AD). In this study, methanol, dichloromethane and aqueous crude extracts from 80 Traditional Chinese Medical (TCM)
Dorothea Kaufmann, Anudeep Kaur Dogra, Ahmad Tahrani, Florian Herrmann, Michael Wink   +4 more
doaj   +1 more source

Polymethoxylated N‐Carboranyl Isoquinolinones: A New Scaffold for ABCG2 Inhibitors

ChemMedChem, Volume 21, Issue 3, 12 February 2026.
Combinations of a boron‐based clusters (carborane) and polymethoxy group patterns are crucial to overcome ABCG2‐mediated multidrug resistance in cancer cells. (Created in BioRender. Kuhnert, L. (2025) https://BioRender.com/h4cnh5m). ABCG2‐mediated multidrug resistance (MDR) is a major challenge among chemotherapeutic treatments of colon, pancreatic ...
Lydia Kuhnert, Philipp Stockmann, Peter Lönnecke, Mara Anna Wolniewicz, Evamarie Hey‐Hawkins, Walther Honscha   +5 more
wiley   +1 more source

Exploration of Antiplasmodium Chemical Space Identifies New Inhibitors of β‐Hematin Formation from Areas of Enrichment

ChemMedChem, Volume 21, Issue 3, 12 February 2026.
An enrichment map, developed using principal components analysis (PCA), shows the relative abundance of inhibitors of synthetic hemozoin (β‐hematin) formation in antiplasmodium chemical space. This 2‐dimensional landscape can be mined to unearth new chemotypes for antimalarial drug development.
Jessica L. Thibaud, Dirkie C. Myburgh, Rebecca D. Sandlin, Kim Y. Fong, Larnelle F. Garnie, Kathryn J. Wicht, David Kuter, David W. Wright, Timothy J. Egan, Katherine A. de Villiers   +9 more
wiley   +1 more source