Results 111 to 120 of about 15,657 (274)

Natural products targeting tumour angiogenesis

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.
Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu   +2 more
wiley   +1 more source

The Biological Activity of Natural Alkaloids against Herbivores, Cancerous Cells and Pathogens [PDF]

open access: yes, 2019
The growing incidence of microorganisms that resist antimicrobials is a constant concern for the scientific community, while the development of new antimicrobials from new chemical entities has become more and more expensive, time-consuming, and ...
Bader, Mariam   +6 more
core   +2 more sources

Differential gene expression toward species of Aristolochia impairing the performance of the Troidini butterfly Battus polydamas

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
We studied the response of Battus polydamas (Papilionidae) larvae fed on Aristolochia ringens (containing several diterpenes) and Aristolochia gigantea (containing sesquiterpenes and acyclic monoterpenoids but no diterpenoids or aristolochic acids). We assessed larval performance on fitness components such as survival and differential gene expression ...
Karina L. Silva‐Brandão   +3 more
wiley   +1 more source

Enhanced CO2 Coordinates the Spatial Recruitment of Diazotrophs in Rice Via Root Development

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Understanding the reciprocal interaction between root development and coadapted beneficial microbes in response to elevated CO2 (eCO2) will facilitate the identification of nutrient‐efficient cultivars for sustainable agriculture. Here, systematic morphological, anatomical, chemical and gene expression assays performed under low‐nitrogen ...
Junwen Zhao   +12 more
wiley   +1 more source

Multiple, Single Trait GWAS and Supervised Machine Learning Reveal the Genetic Architecture of Fraxinus excelsior Tolerance to Ash Dieback in Europe

open access: yesPlant, Cell &Environment, Volume 48, Issue 5, Page 3793-3809, May 2025.
ABSTRACT Common ash (Fraxinus excelsior) is under intensive attack from the invasive alien pathogenic fungus Hymenoscyphus fraxineus, causing ash dieback at epidemic levels throughout Europe. Previous studies have found significant genetic variation among genotypes in ash dieback susceptibility and that host phenology, such as autumn yellowing, is ...
James M. Doonan   +19 more
wiley   +1 more source

Advances in the Preparation of Fluorinated Isoquinolines: A Decade of Progress

open access: yesJournal of Chemistry, 2017
Heterocyclic molecules incorporating fluorinated isoquinoline components are found in many medicinally and agriculturally important bioactive products as well as industrially impactful materials.
Joseph C. Sloop
doaj   +1 more source

Oxyntomodulin physiology and its therapeutic development in obesity and associated complications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Physiological influences of OXM and its emerging insights from evidence on bariatric surgery effects. CCK, cholecystokinin; FGF21, fibroblast growth factor 21; GLUT4, glucose transporter type 4; IRS1, insulin receptor substrate‐1; NNMT, nicotinamide N‐methyltransferase; OXM, oxyntomodulin Abstract Incretins, such as glucagon‐like
Martin T. W. Kueh   +3 more
wiley   +1 more source

Recent Advances in Palladium‐Catalyzed Phosphonation of Aryl Halides, Sulfonates and Related Derivatives

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 20, May 28, 2025.
This review provides an in‐depth exploration of recent progress in palladium‐catalyzed phosphonation, focusing on the use of aryl halides, sulfonates and related derivatives as key substrates. It discusses innovations in catalytic systems, reaction conditions, and substrate versatility while addressing limitations such as low reactivity of certain ...
YiYi Yang, On Ying Yuen, Chau Ming So
wiley   +1 more source

Synthesis, characterization and antimicrobial investigation of new piperidinyl tetrahydrothieno[2,3-c]isoquinolines

open access: yesArabian Journal of Chemistry, 2021
Herein, we describe the synthesis of novel piperidinyl thieno tetrahydroisoquinolines attached or fused to other new heterocycles. The diazotization of the previously synthesized pyrrolyl carbohydrazide 1 followed by several reactions with ethanol ...
Remon M. Zaki   +4 more
doaj  

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