Results 21 to 30 of about 15,657 (274)
Orthogonal Synthesis of Indolines and Isoquinolines via Aryne Annulation [PDF]
, 2008 Described in this report is the development of two unique methodologies exploiting the reactivity of arynes. Reaction of N-carbamoyl-functionalized enamine derivatives with benzyne affords substituted indolines. An orthogonal reactivity is uncovered when
Allan, Kevin M. +2 more
core +1 more source
Synthesis and Anti-HIV Activity of a Novel Series of Isoquinoline-Based CXCR4 Antagonists
Molecules, 2021 An expansion of the structure–activity relationship study of CXCR4 antagonists led to the synthesis of a series of isoquinolines, bearing a tetrahydroquinoline or a 3-methylpyridinyl moiety as head group.
Mastaneh Safarnejad Shad +6 more
doaj +1 more source
A rational protocol for the synthesis of 1-(2-pyridyl)isoquinolines [PDF]
, 2013 Aza-Diels-Alder reaction between 3-(2-pyridyl)-1,2,4-triazines and 1-morpholinocyclohexene followed by aromatization of the cyclohexene moiety affords 1-(2-pyridyl)isoquinolines.
Chupakhin, O. N. +7 more
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A novel approach to oxoisoaporphine alkaloids via regioselective metalation of alkoxy isoquinolines
Beilstein Journal of Organic Chemistry, 2017 Oxoisoaporphine alkaloids are conveniently prepared via direct ring metalation of alkoxy-substituted isoquinolines at C-1, followed by reaction with iodine.
Benedikt C. Melzer, Franz Bracher
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2023 The three-component reaction of isoquinolines, dialkyl acetylenedicarboxylates, and 5,6-unsubstituted 1,4-dihydropyridines in acetonitrile at room temperature afforded functionalized isoquinolino[1,2-f][1,6]naphthyridines in good yields and with high ...
Xiu-Yu Chen +4 more
doaj +1 more source
Dissociative Photoionization of Quinoline and Isoquinoline [PDF]
The Journal of Physical Chemistry A, 2015 Two nitrogen-containing polycyclic aromatic hydrocarbon isomers of C9H7N composition, quinoline, and isoquinoline have been studied by imaging photoelectron photoion coincidence spectroscopy at the VUV beamline of the Swiss Light Source. High resolution threshold photoelectron spectra have been recorded and are interpreted applying a Franck-Condon ...
Jos Oomens +5 more
openaire +5 more sources
1,3-Dipolar cycloadditions of azomethine imines [PDF]
, 2015 Azomethine imines are considered 1,3-dipoles of the aza-allyl type which are transient intermediates and should be generated in situ but can also be stable and isolable compounds.
Nájera, Carmen +2 more
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Molecules, 2013 An efficient approach for the synthesis of biologically interesting fused tetracyclic isoquinolines in high yields and with a broad substrate scope has been developed. The strategy features an AgNO3 catalyzed ‘one-pot’ cascade process
Jian Li +5 more
doaj +1 more source
Molecules, 2022 A mild and efficient strategy for the synthesis of tricyclic 1,2,4-oxadiazolines-fused tetrahydro-isoquinolines derivatives via [3 + 2] cycloaddition reaction is reported.
Kaikai Wang +6 more
doaj +1 more source
Fluorescent annulated imidazo[4,5-c]isoquinolines via a GBB-3CR/imidoylation sequence - DNA-interactions in pUC-19 gel electrophoresis mobility shift assay [PDF]
, 2022 Herein we report the development of a sequential synthesis route towards annulated imidazo[4,5-c]isoquinolines comprising a GBB-3CR, followed by an intramolecular imidoylative cyclisation.
Adam, C. R. +7 more
core +3 more sources