Results 71 to 80 of about 29,358 (323)

The Azidofunctionalization of Alkenes

ChemistryEurope, EarlyView.
The azidofunctionalization of alkenes offers a powerful strategy for synthesizing nitrogen‐containing compounds by installing both an azide and a second functional group in one step. This approach, employing photoredox catalysis, transition metals, and radical methods, is efficient, selective, and versatile, with applications in pharmaceuticals and ...
Pierre Palamini, Jerome Waser
wiley   +1 more source

Anti-Inflammatory Activity of Alkaloids: An Update from 2000 to 2010

Molecules, 2011
Many natural substances with proven anti-inflammatory activity have been isolated throughout the years. The aim of this review is to review naturally sourced alkaloids with anti-inflammatory effects reported from 2000 to 2010.
Margareth de Fátima Formiga Melo Diniz, José Maria Barbosa Filho, Petrônio Filgueiras de Athayde-Filho, Marcelo Sobral da Silva, Josean Fechine Tavares, Augusto Lopes Souto   +5 more
doaj   +1 more source

Stereochemical studies on protonated bridgehead amines. ^1H NMR determination of cis and trans B-C ring-fused structures for salts of hexahydropyrrolo [2,1-a] isoquinolines and related C ring homologs. Capture of unstable ring-fused structures in the solid state [PDF]

, 1989
Acid-addition salts of tricyclic isoquinolines 2a/b, 3a/b, 4a-4c, 5, 6a/b, 7, 8a/b, 9a/b, and 17a/b were studied by high-field ^1H NMR in CDCl_3 solution.
Inners, Ruth R., Maryanoff, Bruce E., Mayo, Stephen L., McComsey, David F., Mutter, Martin S., Olofson, R. A., Wooden, Gary P.   +6 more
core  

Conversion of Amides into Esters by the Nickel-Catalyzed Activation of Amide C-N Bonds [PDF]

, 2015
The amide function is ubiquitous in natural compounds as well as in man-made molecules and materials. It is generally very stable and poorly reactive owing to its resonance-stabilized C–N group that imparts a planar geometry to amides.
A Greenberg, BM Rosen, DL Van Vranken, EH White, EJ Corey, Emma L. Baker, GE Keck, H Tatamidani, H Xu, JP Guthrie, JT Spletstoser, K Amaike, K Brix, K. N. Houk, KW Quasdorf, L Pauling, Liana Hie, M Blangetti, M Tobisu, NA Stephenson, Neil K. Garg, Noah F. Fine Nathel, Peng Liu, Q Lu, S Nahm, S-i Nishimoto, SB Blakey, SZ Tasker, T Hudlicky, T Mesganaw, T Mesganaw, T Shiba, T Yamamoto, TA Dineen, Tejas K. Shah, X Hong, X-Q Zhang, Xin Hong, Yun-Fang Yang   +38 more
core   +2 more sources

Catalyst-Controlled [3 + 2] and [4 + 2] Annulations of Oximes with Propargyl Alcohols: Divergent Access to Indenamines and Isoquinolines.

Organic Letters, 2018
Rhodium(III)- and iridium(III)-catalyzed C-H activation of oximes and coupling with propargyl alcohols is discussed. Depending on the catalyst, the reaction pathway switched between [3 + 2] and [4 + 2] annulations, thus giving divergent access to ...
Wanchun Gong, Zhi Zhou, Jingjing Shi, Bo Wu, Biyun Huang, Wei Yi   +5 more
semanticscholar   +1 more source

“On Water” Photochemistry: Visible‐Light‐Induced Synthesis of Diaryl Sulfides by Nitrogen Extrusion

ChemistryEurope, EarlyView.
This study demonstrates an efficient and versatile blue light‐mediated synthesis of dissymmetric diaryl sulfides by nitrogen photoextrusion from diarylazo sulfides. The reaction is carried out “on water” without the need for (photo)catalysts or additives.
Hawraz Ibrahim M. Amin, Lorenzo Di Terlizzi, Chiara Milanese, Stefano Protti, Maurizio Fagnoni   +4 more
wiley   +1 more source

N-formylation of isoquinoline derivatives with CO2 and H2 over a heterogeneous Ru/ZIF-8 catalyst

Journal of Experimental Nanoscience, 2022
Chemical utilization of CO2 is one of the fundamental strategies to synthesize value-added chemicals and reduce the CO2 emission. N-formyl-1,2,3,4-tetrahydroisoquinoline derivatives (FTHIQs) are important chemicals for the synthesis of medical ...
Zhen-Hong He, Yuan-Yuan Wei, Na Li, Yong-Chang Sun, Shao-Yan Yang, Kuan Wang, Weitao Wang, Xiaoxue Ma, Zhao-Tie Liu   +8 more
doaj   +1 more source

Allosteric interactions at adenosine A1 and A3 receptors: new insights into the role of small molecules and receptor dimerization [PDF]

, 2013
Keywords:adenosine;allosterism;receptor;GPCR;dimerization;biased signalling The purine nucleoside adenosine is present in all cells in tightly regulated concentrations. It is released under a variety of physiological and pathophysiological conditions to
Albrecht-Kupper, Alexander, Amoah-Apraku, Aurelio, Aurelio, Avlani, Azzi, Baker, Baker, Bar-Yehuda, Bar-Yehuda, Baraldi, Baraldi, Barbhaiya, Briddon, Bruns, Bruns, Carr, Casadó, Chandrasekera, Chen, Chiavegatta, Chien, Christopoulos, Christopoulos, Chung, Ciruela, Clark, Cohen, Cordeaux, Corriden, Corriden, Cristovao-Ferreira, Dowling, Du, Dubey, Ellis, Fishman, Franco, Fredholm, Gao, Gao, Gao, Gao, Ge, Gessi, Goedeke, Goldman, Graaf, Gracia, Gracia, Griffin, Göblyös, Göblyös, Han, Harrison, Heitman, Hern, Hu, Ilien, Jaakola, Jacobson, Jacobson, Janusz, Kenakin, Kenakin, Keov, Kimatrai-Salvador, Klaft, Klein, Knapp, Kostenis, Kourounakis, Kuszak, Langemeijer, Lazareno, Lee, Lee, Lee, Limbird, Liu, Madi, Mares, Matherne, May, May, May, May, McCrea, Meno, Merighi, Morrison, Muller, Nikolakopoulos, Park, Peeters, Pisterzi, Rasmussen, Romagnoli, Roth, Salvatore, Smith, Sowa, Springael, Street, Suzuki, Swaminath, Tendera, Tinney, Uematsu, Urizar, Valant, Whalen, Williams, Xu   +114 more
core   +2 more sources

Three-Component Cascade Bis-heteroannulation of Aryl or Vinyl Methylketoxime Acetates toward Thieno[3,2-c]isoquinolines.

Organic Letters, 2019
A three-component cascade bis-heteroannulation reaction is described that provides access to a variety of benzo[4,5]thieno[3,2-c]isoquinoline and thieno[3,2-c]isoquinoline compounds from easily available methylketoximes, o-halobenzaldehydes, and ...
Zhenhua Xu, G. Deng, Feng Zhang, Hongbiao Chen, Huawen Huang   +4 more
semanticscholar   +1 more source

A Family of Symmetrical and Unsymmetrical Aza‐Dipyrromethenes and Aza‐BODIPYs with Through‐Bond and Face‐To‐Face π‐Interaction between Termini

Chemistry – A European Journal, EarlyView.
The reported aza‐dibenzodiprromethenes present a rare helical architecture, placing terminal aryl groups in a close, π‐stacked arrangement. Differentially terminated derivatives are prepared by statistical condensation or controlled synthesis via conversion of one partner to its tosylate or triflate.
Budur N. Alanazi, Ahad O. Alsahli, Sonia Remiro‐Buenamañana, Alejandro Díaz‐Moscoso, Faeza H. Alkorbi, Norah A. Alsaiari, Conor Marrett‐Munro, Isabelle Chambrier, David L. Hughes, Simon J. Coles, Graham J. Tizzard, Andrew N. Cammidge   +11 more
wiley   +1 more source