Results 91 to 100 of about 871 (158)

Enantioconvergent copper-catalysed difluoromethylation of alkyl halides. [PDF]

Nat Catal
Ding D, Yin L, Poore AT, Ho YS, Cheng YH, Hsieh CT, Yachuw SC, Knieser RM, Krause JA, Tian S, Cheng MJ, Liu W.   +11 more
europepmc   +1 more source

Nitropyridines in the Synthesis of Bioactive Molecules. [PDF]

Pharmaceuticals (Basel)
Starosotnikov A, Bastrakov M.
europepmc   +1 more source

Stereoselective Amine Synthesis Mediated by a Zirconocene Hydride to Accelerate a Drug Discovery Program. [PDF]

J Org Chem
Aloiau AN, Bobek BM, Caddell Haatveit K, Pearson KE, Watkins AH, Jones B, Smith CR, Ketcham JM, Marx MA, Harwood SJ.   +9 more
europepmc   +1 more source

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Isothiazoles

Angewandte Chemie International Edition in English, 1963
AbstractThe ring system of non‐anellated 1,2‐thiazoles (isothiazoles) has only recently become accessible. Four syntheses and numerous interconversions have opened up new routes to compounds which command interest as intermediates and as analogues of natural products and established pharmaceuticals.
F. Hübenett, H. D. Hofmann
openaire   +2 more sources

Isothiazoles

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
D. W. Brown, M. Sainsbury
openaire   +1 more source

Isothiazoles. Part XIII. Isothiazole sulphides and sulphones

Journal of the Chemical Society C: Organic, 1971
The synthesis of di-isothiazolyl sulphides and their oxidation to sulphoxides and sulphones are described. Isothiazolylphenyl sulphones are prepared by condensation of sodium benzenesulphinates and 5-bromo-3-methyl-4-nitroisothiazole. None of these compounds possess useful biological properties.
M. P. L. Caton, G. C. J. Martin, D. L. Pain   +2 more
openaire   +1 more source

Isothiazoles. Part 12: Isothiazolylphosphonates, a new class of isothiazole dioxides

Tetrahedron, 2001
Abstract We describe a mild and efficient method to prepare 3-amino-4,5-dihydro-5-isothiazolylphosphonates from 3-amino-5-unsubstituted isothiazole dioxides. Starting from 3-amino-5-bromo-isothiazole dioxides either 3-amino-5-isothiazolylphosphonates or 5-diethoxyphosphoryl-4,5-dihydro-4-isothiazolylphosphonates were prepared ...
F. Clerici, M.L. Gelmi, E.R.E. Pini, M. Valle   +3 more
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The Chemistry of Isothiazoles

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Condensed isothiazoles. Part 5. Thieno[2,3-d]isothiazoles and thieno[3,2-d]isothiazoles

Journal of the Chemical Society, Perkin Transactions 1, 1980
2,3-Disubstituted thiophens containing a sulphur function (SH, SMe, or SCN) and a carbonyl group (CHO or Ac) have been prepared and converted into thieno[2,3-d or 3,2-d]isothiazoles. Methods used to prepare 1,2-benzisothiazoles are often inapplicable in the thiophen series. For example, an (E)-methyl (2-methylthio-3-thienyl)O-p-nitrobenzoylketoxime (6)
Kenneth Clarke, William Richard Fox, Richard M. Scrowston   +2 more
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Isothiazoles. Part XII. Isothiazole analogues of phenothiazines

Journal of the Chemical Society C: Organic, 1968
The syntheses of isothiazole analogues [(V) and (VI)] of certain phenothiazines and 4-substituted phenothiazines, where the substituent is dialkylaminoalkyl, 1-piperazinylalkyl, or piperidinoalkyl are described. None of these possesses advantageous pharmacological properties.
M. P. L. Caton, R. Slack
openaire   +1 more source