Results 141 to 150 of about 254,991 (338)

Isothiocyanates for Human Health [PDF]

Molecular Nutrition & Food Research, 2018
Richard, Mithen, Emily, Ho
openaire   +2 more sources

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Cruciferous vegetable intake and cardiovascular disease risk in the Framingham Offspring Cohort [PDF]

, 2019
Fruit and vegetable intake has been demonstrated to be inversely correlated with CVD risk, but it remains to be elucidated whether different subclasses of fruits and vegetables and their bioactive constituents have different effects on CVD risk ...
Sager, Jenna
core  

A 14-day repeated-dose oral toxicological evaluation of an isothiocyanate-enriched hydro-alcoholic extract from Moringa oleifera Lam. seeds in rats

, 2018
Youjin Kim, Asha Jaja-Chimedza, Daniel R. Merrill, Odete Mendes, Ilya Raskin   +4 more
openalex   +2 more sources

TRPA1 Agonists—Allyl Isothiocyanate and Cinnamaldehyde—Induce Adrenaline Secretion [PDF]

, 2008
Yusaku Iwasaki, Manabu Tanabe, Kenji Kobata, Tatsuo Watanabe   +3 more
openalex   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

Supplementary Figure 1 from Atg5 Regulates Phenethyl Isothiocyanate–Induced Autophagic and Apoptotic Cell Death in Human Prostate Cancer Cells

, 2023
Ajay Bommareddy, Eun‐Ryeong Hahm, D. Xiao, Anna A. Powolny, Alfred L. Fisher, Yu Jiang, Shivendra V. Singh   +6 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Editorial: Glucosinolate Metabolites: Bioavailability, Bioactivity and Clinical Variability

Frontiers in Nutrition, 2021
Donato Angelino, Elizabeth H. Jeffery
doaj   +1 more source

Allyl isothiocyanate exacerbates acute toxoplasmosis through inhibition of inflammatory cytokines [PDF]

Qiu-Mei Lin, Hong-bin Long, JF He, Zhihao Zhang, Ho-Woo Nam, Fu‐Shi Quan, Qi Zhong, Xuqing Liu, Zhaoshou Yang   +8 more
openalex   +1 more source