Results 141 to 150 of about 266,552 (386)

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche   +16 more
wiley   +1 more source

High‐Throughput Encapsulation of Stem Cells: Characterizing Dynamic Culture Variability With a Millifluidic Approach

open access: yesAdvanced Healthcare Materials, EarlyView.
A high throughput millifluidic encapsulation platform is engineered and standardized. The system's output allows the monitoring of cell expansion in strong dynamic conditions. High polymer crosslinking leads to higher cell proliferation and lower cell growth on microgel's surface.
Oscar Fabian García‐Aponte   +6 more
wiley   +1 more source

Isothiocyanate-Functionalized Mesoporous Silica Nanoparticles as Building Blocks for the Design of Nanovehicles with Optimized Drug Release Profile

open access: yesNanomaterials, 2019
A straightforward methodology for the synthesis of isothiocyanate-functionalized mesoporous silica nanoparticles (MSNs) by exposure of aminated MSNs to 1,1′-thiocarbonyldi-2(1H)-pyridone is reported. These nanoparticles are chemically stable, water
Gabriel Martínez-Edo   +3 more
doaj   +1 more source

In vitro screening of the effect of three glucosinolate derived nitriles on soil-borne fungi [PDF]

open access: yes, 2006
Glucosinolates are allelochemicals present in all plants of the order Capparales that are hydrolysed by endogenous enzymes (myrosinases) forming a variety of compounds with biological activity.
Bellostas, Natalia   +4 more
core  

Generalizing Gelatin Methacryloyl Granular Hydrogel Fabrication Using Stable Microgels with Predictable Stiffness

open access: yesAdvanced Healthcare Materials, EarlyView.
Gelatin methacryloyl (GelMA) granular hydrogel scaffolds (GHS) are fabricated using a generalized two‐step photocrosslinking approach to yield stable (non‐dissolving) microgels suitable for in situ covalent assembly under physiological conditions. A phase diagram is developed to define the interplay between individual microgel stability and scaffold ...
Yuanhui Xiang   +4 more
wiley   +1 more source

RBC Membrane‐Camouflaged Nanosystem‐Mediated Synergistic Drug Combination for Enhanced Anti‐Tumor Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng   +6 more
wiley   +1 more source

Magnetic‐Driven Torque‐Induced Electrical Stimulation for Millisecond‐Scale Wireless Neuromodulation

open access: yesAdvanced Healthcare Materials, EarlyView.
MagTIES is a wireless neuromodulation technique with millisecond precision. It employs magnetic‐driven torque from magnetite nanodiscs to activate piezoelectric nanoparticles, enabling precise temporal control of neuronal activity and brain oscillations using weak, low‐frequency magnetic fields.
Chao‐Chun Cheng   +5 more
wiley   +1 more source

Effect on yield, total phenolic, total flavonoid and total isothiocyanate content of two broccoli cultivars (Brassica oleraceae var italica) following the application of a commercial brown seaweed extract (Ascophyllum nodosum)

open access: yes, 2014
Field experiments were conducted to evaluate the effect of an unfortified extract, of Ascophyllum nodosum on yield and nutritional quality of two broccoli cultivars (‘Ironman’ and ‘Red Admiral’). Total phenolic, total flavonoid, and total isothiocyanates
T. Lola-Luz, F. Hennequart, M. Gaffney
semanticscholar   +1 more source

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