Results 171 to 180 of about 20,151 (240)

Attenuated Nuclear Tension Regulates Progerin‐Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling

Advanced Science, EarlyView.
The premature aging‐related progerin leads to defective nuclear morphology and is associated with disrupted molecular coupling between the extranuclear cytoskeleton and lamin‐associated nuclear envelope. It is discovered that progerin expression reduces nuclear tension, forms nuclear wrinkling, and enhances chromatin dynamics, thereby regulating ...
Ji‐Eun Park, Juhyeon Jo, Kun Xu, Sun‐Ah Lee, Seong‐Beom Han, YigJi Lee, Won‐Ki Cho, Bo Li, Soo Hyun Kim, Dong‐Hwee Kim   +9 more
wiley   +1 more source

The clinicopathological significance and relapse predictive role of tumor microenvironment of intrahepatic cholangiocarcinoma after radical surgery

Cancer, Volume 129, Issue 3, Page 393-404, 1 February 2023., 2023
Abstract Background This study attempts to detect the expression of FoxP3, CD68, CD8α, and PD‐L1 in the tumor microenvironment (TME) of intrahepatic cholangiocarcinoma (ICC), and analyze the relationship between the corresponding cells and clinicopathological characteristics as well as prognosis of ICC.
Yiling Zheng, Ning Huang, Shuwen Kuang, Jing Zhang, Hong Zhao, Jianxiong Wu, Mei Liu, Liming Wang   +7 more
wiley   +1 more source

Fluormetric assay for nuclease activity [PDF]

Cytochemical studies of planetary microorganisms - deoxyribonuclease /dnase/ assay, fluorescein reactions, and enzyme ...
Stevens, V. L.
core   +1 more source

A Universal and Versatile Zwitterionic Coating for Blood‐Contacting Catheters with Long Lengths and Complex Geometries

Advanced Science, EarlyView.
A universal and versatile zwitterion coating strategy is developed for blood‐contacting catheters with long lengths and complex geometries. The coating exhibits near‐zero fouling, superior anticoagulation, and selective biocapturing properties while maintaining excellent stability under dynamic blood flow.
Tong Zhang, Tian Liang, Qichao Pan, Shouyan Zhang, Shuhua Zhang, Zhi Geng, Bo Zhu   +6 more
wiley   +1 more source

Automated fluorescence gating and size determination reduce variation in measured concentration of extracellular vesicles by flow cytometry

Cytometry Part A, Volume 101, Issue 12, Page 1049-1056, December 2022., 2022
Abstract Extracellular vesicles (EVs) are an upcoming biomarker for disease. However, the measured concentrations of EVs by flow cytometry are incomparable due to analytical variables. This study aimed to investigate how the choice of fluorophore, and thereby brightness, affects the measured concentration of EVs.
Angela Adriana Francisca Gankema, Bo Li, Rienk Nieuwland, Edwin van der Pol   +3 more
wiley   +1 more source

The effectiveness of different isothiocyanates on attracting larvae of Pieris rapae

, 1963
William Hovanitz, Vincent C S Chang, Gerald Honch   +2 more
openalex   +2 more sources

Interaction of Benzoyl Isothiocyanate and Primary and Secondary Amines : Formation of the Related Benzoylthiocarbamides and Thiocarbamides [PDF]

, 1963
G. Vijayakumaran Nair
openalex   +1 more source

Targeted Penetrating Motif Engineering of BH3 Mimetic: Harnessing Non‐Canonical Amino Acids for Coinhibition of MCL‐1 and BCL‐xL in Acute Myeloid Leukemia

Advanced Science, EarlyView.
A structure‐guided peptide derived from a non‐canonical amino acid library simultaneously targets MCL‐1 and BCL‐xL to overcome apoptotic resistance in acute myeloid leukemia. Fused with a CXCR4‐binding motif, the engineered peptide exhibits selective intracellular delivery and potent in vivo efficacy, offering a promising therapeutic strategy against ...
Zhe Wang, Ruizhi Lai, Xinpei Wang, Xu Chen, Youjian Zhou, Shengbin Li, Xiaohui Qiu, Zekai Zeng, Jianye Yuan, Jinghuan Mao, Zhidong Chen, Junqing Wang   +11 more
wiley   +1 more source

Bioinspired Claw‐Engaged Adhesive Microparticles Armed with γGC Alleviate Ulcerative Colitis via Targeted Suppression of Macrophage Ferroptosis

Advanced Science, EarlyView.
γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang, Jianwei Zhu, Jinyi Zhou, Jinyang Li, Min Wang, Yuqi Wu, Danshan Zhao, Xiancheng Chen, Xiaoyuan Chen, Yuetong Wang, Jianhua Zou   +10 more
wiley   +1 more source

The Thermal Decomposition of Alkoxycarbonyl Thiocyanates and Isothiocyanates [PDF]

, 1975
Dennis C. Liotta, Robert Engel
openalex   +1 more source