Results 171 to 180 of about 59,651 (334)

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Behavior of Acetylenic Ketones and Esters towards Aroylisothiocyanates in Polar Solvent (Part I) [PDF]

, 2009
Reactions of aroylisothiocyanates 2a,b with acetylenic ketones 1a-c gave a mixture of thiocyanatoprop-2-en-1-ones 3a-c, (E,Z)-3,3’-thiodi(1-aryl-3-phenylprop-2-en-1-ones) 4a-c, 4-methoxybenzoylthiourea (6), 3-(4-methoxybenzamido)-1,3-diphenylprop-2-en-1 ...
Hemdan, Magdy, Youssef, Ahmed
core  

New Methods and Reagents in Organic Synthesis. 54. Lithium Trimethylsilylydiazomethane: A New Synthon for the Preparation of 1-Substituted 5-Alkylthio-1,2,3-triazoles from Isothiocyanates

, 1985
Toyohiko Aoyama, Mototsugu Kabeya, Takayuki Shioiri   +2 more
openalex   +1 more source

Structural and Functional Versatility of the Amyloidogenic Non‐Amidated Variant of the Antimicrobial Peptide Citropin 1.3

Advanced Science, EarlyView.
Citropin 1.3 is an antimicrobial peptide derived from amphibians that forms amyloid structures. Here, the structural and functional properties of citropin 1.3 are characterized. Using high‐resolution imaging approaches, a variety of canonical and undescribed fibril morphologies are identified.
Fabio Strati, Mariana Pigozzi Cali, Yehudi Bloch, Siavash Mostafavi, Jim Monistrol, Aleksandr Golubev, Bader Rayan, Emil Gustavsson, Meytal Landau   +8 more
wiley   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

Effects of Food Ingredients on Inactivation of Escherichia coli by Hydrostatic Pressure Treatment with the Addition of Allyl Isothiocyanate.

, 2001
Tetsuro Ogawa, Atsushi Nakatani, Hajime Matsuzaki, Seiichiro Isobe, Kenji Isshiki   +4 more
openalex   +2 more sources

Dual‐Emission Carbon Dot Nanozymes Mitigate Salt Stress and Enhance Photosynthesis for Crop Germination and Growth

Advanced Science, EarlyView.
Dual‐emission carbon dot nanozymes are synthesized via microwave method. The nanozymes enhance photosynthesis corn seedlings through spectral‐matched light conversion. Their superoxide dismutase‐mimetic activity scavenges salt stress‐induced reactive oxygen species and circumvents energy‐intensive stress responses.
Chengfu Su, Xin Peng, Jingying Tan, Yujie Chang, Naifei Pan, Haiying Chen, Xiaokai Xu, Lei Han   +7 more
wiley   +1 more source

Taste and Flavor Perceptions of Glucosinolates, Isothiocyanates, and Related Compounds

Molecular Nutrition & Food Research, 2018
Luke Bell, O. Oloyede, Stella Lignou, C. Wagstaff, L. Methven   +4 more
semanticscholar   +1 more source

Correction: New synthesis of phenyl-isothiocyanate C-functionalised cyclams. Bioconjugation and ⁶⁴Cu phenotypic PET imaging studies of multiple myeloma with the te2a derivative

, 2016
Zakaria Halime, Mathieu Frindel, Nathalie Camus, Pierre-Yves Orain, Marie Lacombe, Karine Bernardeau, Michel Chérel, Jean-François Gestin, A. Faivre-Chauvet, Raphaël Tripier   +9 more
openalex   +2 more sources

Supplementary Table 4 from Effects of Phenylethyl Isothiocyanate on Early Molecular Events in <i>N</i>-Nitrosomethylbenzylamine–Induced Cytotoxicity in Rat Esophagus

, 2023
Rashmeet K. Reen, Alan A. Dombkowski, Laura A. Kresty, Daniela Cukovic, Jennifer M. Mele, Sridevi Salagrama, Ronald Nines, Gary D. Stoner   +7 more
openalex   +1 more source