Results 71 to 80 of about 59,651 (334)

Engineering the Hierarchical Porosity of Granular Hydrogel Scaffolds Using Porous Microgels to Improve Cell Recruitment and Tissue Integration

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
By fabricating and covalently assembling gelatin methacryloyl (GelMA) porous microgels, a new class of granular hydrogel scaffolds with hierarchical porosity is developed. These scaffolds have a significantly higher void fraction than their counterparts made up of nonporous microgels, enhancing cell recruitment and tissue integration. This research may
Alexander Kedzierski, Sina Kheirabadi, Arian Jaberi, Zaman Ataie, Catherine L. Mojazza, Marisa L. Williamson, Anton M. Hjaltason, Aneesh Risbud, Yuanhui Xiang, Amir Sheikhi   +9 more
wiley   +1 more source

An Integrated Metabolomics Study of Glucosinolate Metabolism in Different Brassicaceae Genera

Metabolites, 2020
Glucosinolates are a group of plant secondary metabolites that can be hydrolyzed into a variety of breakdown products such as isothiocyanates, thiocyanates, and nitriles.
Yu Liu, Merja Rossi, Xu Liang, Hui Zhang, Li Zou, Choon Nam Ong   +5 more
doaj   +1 more source

Combining carbohydrate substitutions at bioinspired positions with multivalent presentation towards optimising lectin inhibitors: case study with calixarenes. [PDF]

, 2011
Carbohydrate derivatisation and glycocluster formation are both known to enhance avidity for lectin binding. Using a plant toxin and human adhesion/growth-regulatory lectins (inter- and intrafamily comparisons) the effect of their combination is examined.
André, André, André, André, Cumpstey, Cyrille Grandjean, Dam, Delacour, Fort, Francesco Sansone, François-Moana Gautier, Fulton, Gabius, Galanina, Gautier, Gupta, Hans-Joachim Gabius, Hirabayashi, Jiménez, Kopitz, Krzeminski, Leyden, Oda, Patnaik, Rocco Ungaro, Sabine André, Sanchez-Ruderisch, Sansone, Silvia Bernardi, Sparrow, Sörme, Villalobo, Wu, Wu, Yamazaki   +34 more
core   +2 more sources

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

The Impact of Domestic Cooking Methods on Myrosinase Stability, Glucosinolates and Their Hydrolysis Products in Different Cabbage (Brassica oleracea) Accessions

Foods, 2021
Glucosinolate hydrolysis products are responsible for the health-promoting properties of Brassica vegetables. The impact of domestic cooking on the myrosinase stability, glucosinolates and hydrolysis products in 18 cabbage accession was investigated ...
Omobolanle O. Oloyede, Carol Wagstaff, Lisa Methven   +2 more
doaj   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Comparative Studies of Extracts Obtained from Brassica oleracea L. Plants at Different Stages of Growth by Isolation and Determination of Isothiocyanates: An Assessment of Chemopreventive Properties of Broccoli

Molecules
The main goal of this work was to develop analytical procedures for the isolation and determination of selected isothiocyanates. As an example, particularly sulforaphane from plants of the Brassicaceae Burnett or Cruciferae Juss family.
Magdalena Ligor, Małgorzata Szultka-Młyńska, Katarzyna Rafińska, Agata Cwudzińska   +3 more
doaj   +1 more source

Influence of pH and type of myrosinase complex on the products obtained in the myrosinase catalysed hydrolysis of glucosinolates – a MECC study [PDF]

, 2007
Environmental conditions, e.g. pH and the presence of Fe2+ are well known factors that influence the product profile of the myrosinase catalysed hydrolysis of glucosinolates.
Bellostas, Natalia, Sørensen, Hilmer, Sørensen, Jens C.   +2 more
core  

Anti-cancer activities of allyl isothiocyanate and its conjugated silicon quantum dots [PDF]

, 2018
Allyl isothiocyanate (AITC), a dietary phytochemical in some cruciferous vegetables, exhibits promising anticancer activities in many cancer models. However, previous data showed AITC to have a biphasic effect on cell viability, DNA damage and migration ...
A Bhattacharya, A Lau, A Speciale, AL Sávio, ALV Savio, AR Collins, AZ Wang, Ca Schneider, D Bera, D Xiao, EJ Calabrese, EJ Calabrese, EJ Moon, ES Hwang, F Geng, H Liu, JH Ahire, JV Higdon, JW Fan, K Pietsch, K Tripathi, K Xu, KC Lai, L Mi, L Qi, LM Louhivuori, LS Cooley, M Karin, M Murata, MS Stan, N O’Farrell, P Gupta, P Rajendran, P Shen, P Thejass, P Thejass, P Zrazhevskiy, R Sakhtianchi, RF Clayton, RK Lin, S Ohta, SC Tsai, SK Niture, SK Srivastava, SM Weis, TG Iversen, TG Son, TW Kensler, X Ma, Y Bao, Y Chao, Y Urano, Y Zhang   +52 more
core   +3 more sources

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source