Systematic Review of Rare Major Adverse Cardiovascular Events Associated With the Treatment of Acne With Isotretinoin. [PDF]
Australas J DermatolABSTRACT Acne vulgaris is a common inflammatory condition that is often treated by dermatologists with isotretinoin. Isotretinoin has a number of effects on inflammatory pathways, with clear efficacy in managing acne vulgaris. There are also well‐documented side effects of isotretinoin, including hyperlipidemia; however, the overall cardiovascular risk
Cowan TL +3 more
europepmc +2 more sources
Therapeutic Modulation of Demodex Density via Isotretinoin: Insights From a Prospective Dermatological Investigation. [PDF]
J Cosmet DermatolABSTRACT Aim Demodex spp. are ectoparasites that reside in pilosebaceous units, particularly on the face where sebum secretion is prominent. The sebum‐reducing effects of isotretinoin play a crucial role in the management of acne vulgaris and rosacea. This study aims to assess the effect of isotretinoin on Demodex density in patients with acne vulgaris
Chakmakchi AMJ +4 more
europepmc +2 more sources
Pregnancy and isotretinoin therapy [PDF]
Canadian Medical Association Journal, 2013 A 29-year-old woman was given isotretinoin for severe, recalcitrant acne. During the first 3 months of treatment, she was taking an oral contraceptive agent that she had started at the same time as the isotretinoin.
Irena Nulman +2 more
openaire +9 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Gender matter in isotretinoin therapy for acne vulgaris? A retrospective study [PDF]
, 2015 Introduction: Gender differences have been recently highlighted for several aspects of acne vulgaris such as epidemiology, pathogenesis, clinical course, quality of life and treatment outcome.
Balduzzi, Veronica +9 more
core +1 more source
Isotretinoin Hepatotoxicity or Isotretinoin Induced Autoimmune Hepatitis?
Indian Journal of Paediatric Dermatology, 2021 While isotretinoin, a drug used for the treatment of severe nodulocystic acne, is known to be hepatotoxic, an association with autoimmune hepatitis (AIH) has not been suggested so far. A 17-year-old girl diagnosed with AIH following isotretinoin use for acne vulgaris is presented, and the differences between isotretinoin hepatotoxicity and isotretinoin
Şükrü Güngör +3 more
openaire +3 more sources
Isotretinoin and psychopathology: a review [PDF]
Annals of General Psychiatry, 2009 AbstractIsotretinoin, a synthetic oral retinoid that is used against severe nodulocystic acne, has been associated with various psychiatric side effects such as depression, suicidality and psychotic symptoms. A great number of reports on its effects have been published since its introduction into the market.
Panayotis Ferentinos +4 more
openaire +4 more sources
Muir-Torre syndrome - Treatment with isotretinoin and interferon alpha-2a can prevent tumour development [PDF]
, 2000 Muir-Torre syndrome is a genodermatosis in which multiple internal malignancies are associated with cutaneous sebaceous tumours and kerato-acanthomas. A 57-year-old man presented with multiple sebaceous tumours, kerato-acanthomas, verrucous carcinoma of ...
Burgdorf, Walter H. C. +3 more
core +1 more source
Oral isotretinoin for acne [PDF]
Cochrane Database of Systematic Reviews, 2011 Acne vulgaris, a chronic inflammatory disease of the pilosebaceous unit associated with socialisation and mental health problems, may affect more than 80% of teenagers. Isotretinoin is the only drug that targets all primary causal factors of acne; however, it may cause adverse effects.To assess efficacy and safety of oral isotretinoin for acne vulgaris.
Costa, Caroline S. +6 more
openaire +3 more sources
Severe osteoarticular involvement in isotretinoin-triggered acne fulminans: two cases successfully treated with anakinra. [PDF]
, 2017 Acne fulminans (AF) is a severe form of inflammatory and ulcerated acne associated with fever, malaise, joint swellings and polyarthralgia.1 Osteoarticular lesions are often described and can be radiologically indistinguishable from those observed in
Barbareschi +9 more
core +1 more source