Results 11 to 20 of about 23,093 (215)

Oral isotretinoin and sacroiliitis: causal link or coincidence? Discussion points emerging from a case-based review

open access: yesRheumatology, 2022
Isotretinoin is a retinoid derivative drug used in acne vulgaris treatment. Sacroiliitis has been reported as an uncommon adverse effect following isotretinoin treatment.
Betül Sargin, Ciro Manzo
doaj   +1 more source

Adverse Events in Isotretinoin Therapy: A Single-Arm Meta-Analysis

open access: yesInternational Journal of Environmental Research and Public Health, 2022
Isotretinoin (ISO) is an oral prescription-only retinoid, well known for its acne-treating effect. However, it affects a substantial number of human cell types, causing a broad spectrum of adverse effects.
J. Kapała   +3 more
semanticscholar   +1 more source

Isotretinoin and adverse neuropsychiatric outcomes: retrospective cohort study using routine data

open access: yesBritish Journal of Dermatology, 2022
Severe neuropsychiatric outcomes have been reported in individuals exposed to isotretinoin, but the evidence is inconclusive and complicated by several methodological limitations.
T. Paljarvi   +4 more
semanticscholar   +1 more source

Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway

open access: yesInvestigative Ophthalmology and Visual Science, 2022
Purpose To investigate the effects of isotretinoin on the ocular surface and to explore the possible mechanisms. Methods Rats were treated with isotretinoin 20 mg/kg/d for five months and tested monthly for tear secretion, fluorescein staining, and ...
Peng Zhang   +7 more
semanticscholar   +1 more source

Isotretinoin treatment upregulates the expression of p53 in the skin and sebaceous glands of patients with acne vulgaris

open access: yesArchives of Dermatological Research, 2022
The transcriptomic regulation induced by isotretinoin (13-cis retinoic acid) is still a matter of debate as short-term exposures of immortalized sebocytes with isotretinoin produced conflicting results.
N. Agamia   +9 more
semanticscholar   +1 more source

Prevalence and associated risk factors of acne relapse among Saudi acne vulgaris patients using isotretinoin

open access: yesSaudi Pharmaceutical Journal, 2020
Background: Acne vulgaris is a self-limiting condition that may affect the patients quality of life. The most efficacious treatment of choice for acne is isotretinoin.
Alshammari SA   +5 more
doaj   +1 more source

Isotretinoin Hepatotoxicity or Isotretinoin Induced Autoimmune Hepatitis?

open access: yesIndian Journal of Paediatric Dermatology, 2021
While isotretinoin, a drug used for the treatment of severe nodulocystic acne, is known to be hepatotoxic, an association with autoimmune hepatitis (AIH) has not been suggested so far.
Fatma Ilknur Varol   +3 more
doaj   +1 more source

Patients' Knowledge and Information Needs about Isotretinoin Therapy Use in Jordan

open access: yesInternational journal of clinical practice, 2022
Background. Despite being the first‐line treatment for severe or moderate acne, isotretinoin has several serious side effects that necessitate the evaluation of patients’ knowledge about isotretinoin side effects and its proper use. Objective.
A. Jarab   +3 more
semanticscholar   +1 more source

Isotretinoin exposure in pregnant women in Korea [PDF]

open access: yesObstetrics & Gynecology Science, 2018
ObjectiveIsotretinoin is a notorious teratogen otherwise used for the treatment of acne vulgaris. Some countries, including those in North America and the European Union, implemented the pregnancy prevention program (PPP); however, no PPP has yet been ...
Nae Ry Kim   +9 more
doaj   +1 more source

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