Results 11 to 20 of about 33,246 (294)
Multimodal Management of Morbihan Disease: Isotretinoin, Intralesional Triamcinolone, and Ketotifen in a Recalcitrant Case. [PDF]
CureusMoreno BA +2 more
europepmc +3 more sources
Acne Transcriptomics: Fundamentals of Acne Pathogenesis and Isotretinoin Treatment
Cells, 2023 This review on acne transcriptomics allows for deeper insights into the pathogenesis of acne and isotretinoin’s mode of action. Puberty-induced insulin-like growth factor 1 (IGF-1), insulin and androgen signaling activate the kinase AKT and mechanistic ...
Bodo C Melnik
semanticscholar +1 more source
Risk of Suicide and Psychiatric Disorders Among Isotretinoin Users
JAMA dermatology, 2023 Key Points Question Is isotretinoin use associated with the risk of suicide and psychiatric disorders? Findings In this meta-analysis of 25 studies including 1 625 891 participants, the 1-year absolute risk of completed suicide, suicide attempt, suicide ...
N. Tan +4 more
semanticscholar +1 more source
Ocular side effects of systemic isotretinoin – a systematic review and summary of case reports
Journal of dermatological treatment (Print), 2023 Background: Isotretinoin is frequently used for treatment of severe nodulocystic and papulopustular acne, however use is limited by mucocutaneous, ocular, and systemic side effects. Objective: (1) provide a systematic meta-analysis of ocular side effects
Olivia Lamberg +6 more
semanticscholar +1 more source
Dendrimer-conjugated isotretinoin for controlled transdermal drug delivery
Journal of Nanobiotechnology, 2023 Background In the present study, we aimed to develop a novel isotretinoin delivery model for treating skin diseases, revealing its potential advantages in drug delivery and targeted therapy.
Tianqi Zhao +6 more
semanticscholar +1 more source
Rheumatology, 2022 Isotretinoin is a retinoid derivative drug used in acne vulgaris treatment. Sacroiliitis has been reported as an uncommon adverse effect following isotretinoin treatment.
Betül Sargin, Ciro Manzo
doaj +1 more source
Experimental Dermatology, 2023 There are no drugs as effective as isotretinoin for acne. Deciphering the changes in the microbiome induced by isotretinoin in the pilosebaceous follicle of successfully treated patients can pave the way to identify novel therapeutic alternatives.
Z. Nolan +10 more
semanticscholar +1 more source
Adverse Events in Isotretinoin Therapy: A Single-Arm Meta-Analysis
International Journal of Environmental Research and Public Health, 2022 Isotretinoin (ISO) is an oral prescription-only retinoid, well known for its acne-treating effect. However, it affects a substantial number of human cell types, causing a broad spectrum of adverse effects.
J. Kapała +3 more
semanticscholar +1 more source
Saudi Pharmaceutical Journal, 2020 Background: Acne vulgaris is a self-limiting condition that may affect the patients quality of life. The most efficacious treatment of choice for acne is isotretinoin.
Alshammari SA +5 more
doaj +1 more source
Isotretinoin Hepatotoxicity or Isotretinoin Induced Autoimmune Hepatitis?
Indian Journal of Paediatric Dermatology, 2021 While isotretinoin, a drug used for the treatment of severe nodulocystic acne, is known to be hepatotoxic, an association with autoimmune hepatitis (AIH) has not been suggested so far.
Fatma Ilknur Varol +3 more
doaj +1 more source