Results 21 to 30 of about 33,246 (294)
Isotretinoin and adverse neuropsychiatric outcomes: retrospective cohort study using routine data
British Journal of Dermatology, 2022 Severe neuropsychiatric outcomes have been reported in individuals exposed to isotretinoin, but the evidence is inconclusive and complicated by several methodological limitations.
T. Paljarvi +4 more
semanticscholar +1 more source
Isotretinoin exposure in pregnant women in Korea [PDF]
Obstetrics & Gynecology Science, 2018 ObjectiveIsotretinoin is a notorious teratogen otherwise used for the treatment of acne vulgaris. Some countries, including those in North America and the European Union, implemented the pregnancy prevention program (PPP); however, no PPP has yet been ...
Nae Ry Kim +9 more
doaj +1 more source
Archives of Dermatological Research, 2022 The transcriptomic regulation induced by isotretinoin (13-cis retinoic acid) is still a matter of debate as short-term exposures of immortalized sebocytes with isotretinoin produced conflicting results.
N. Agamia +9 more
semanticscholar +1 more source
Acta Dermato-Venereologica, 2020 Two open-label, crossover studies compared the bioavailability of Micronized-isotretinoin 32 mg and Lidose-isotretinoin 40 mg in healthy adults. In the fed bioequivalence/food-effect study, participants (n = 71) received single doses of fed-state ...
Sumit Madan +2 more
doaj +1 more source
Acta Dermato-Venereologica, 2023 Although isotretinoin has anti-inflammatory and immunomodulatory properties, it can exacerbate atopic dermatitis. National estimates of the extent to which patients with atopic dermatitis are affected by severe acne and isotretinoin tolerability are ...
Cathrine H. Mohn +4 more
doaj +1 more source
Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway
Investigative Ophthalmology and Visual Science, 2022 Purpose To investigate the effects of isotretinoin on the ocular surface and to explore the possible mechanisms. Methods Rats were treated with isotretinoin 20 mg/kg/d for five months and tested monthly for tear secretion, fluorescein staining, and ...
Peng Zhang +7 more
semanticscholar +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Comprehensive review of reports of menstrual irregularities associated with isotretinoin
International Journal of Women's Dermatology, 2020 In 1982, oral isotretinoin was first licensed as a treatment option for severe recalcitrant cystic acne in the United States. Since its introduction into the pharmaceutical market, several instances of amenorrhea in women of child-bearing age taking ...
Priya Chelliah, BA +1 more
doaj +1 more source
Premature ventricular contractions associated with isotretinoin use [PDF]
Anais Brasileiros de Dermatologia, 2016 Isotretinoin has been considered a unique drug for acne treatment. However, it is associated with numerous adverse effects. Isotretinoin can trigger premature ventricular contractions.
Sevil Alan +2 more
doaj +1 more source
Patients' Knowledge and Information Needs about Isotretinoin Therapy Use in Jordan
International journal of clinical practice, 2022 Background. Despite being the first‐line treatment for severe or moderate acne, isotretinoin has several serious side effects that necessitate the evaluation of patients’ knowledge about isotretinoin side effects and its proper use. Objective.
A. Jarab +3 more
semanticscholar +1 more source