Results 21 to 30 of about 23,093 (215)

Comparative Pharmacokinetic Profiles of a Novel Low-dose Micronized-isotretinoin 32 mg Formulation and Lidose-isotretinoin 40 mg in Fed and Fasted Conditions: Two Open-label, Randomized, Crossover Studies in Healthy Adult Participants

open access: yesActa Dermato-Venereologica, 2020
Two open-label, crossover studies compared the bioavailability of Micronized-isotretinoin 32 mg and Lidose-isotretinoin 40 mg in healthy adults. In the fed bioequivalence/food-effect study, participants (n = 71) received single doses of fed-state ...
Sumit Madan   +2 more
doaj   +1 more source

Prevalence of Isotretinoin Therapy in Adolescents and Young Adults With and Without Atopic Dermatitis: A Nationwide Prescription-based Population Study

open access: yesActa Dermato-Venereologica, 2023
Although isotretinoin has anti-inflammatory and immunomodulatory properties, it can exacerbate atopic dermatitis. National estimates of the extent to which patients with atopic dermatitis are affected by severe acne and isotretinoin tolerability are ...
Cathrine H. Mohn   +4 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Comprehensive review of reports of menstrual irregularities associated with isotretinoin

open access: yesInternational Journal of Women's Dermatology, 2020
In 1982, oral isotretinoin was first licensed as a treatment option for severe recalcitrant cystic acne in the United States. Since its introduction into the pharmaceutical market, several instances of amenorrhea in women of child-bearing age taking ...
Priya Chelliah, BA   +1 more
doaj   +1 more source

Premature ventricular contractions associated with isotretinoin use [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2016
Isotretinoin has been considered a unique drug for acne treatment. However, it is associated with numerous adverse effects. Isotretinoin can trigger premature ventricular contractions.
Sevil Alan   +2 more
doaj   +1 more source

Teratogenic effect of isotretinoin in both fertile females and males (Review).

open access: yesExperimental and Therapeutic Medicine, 2021
Isotretinoin is an oral derivate of vitamin A that has been used since 1982 for the treatment of multiple dermatologic conditions such as severe acne, rosacea, scarring alopecia, ichthyosis or non-melanoma skin cancer prophylaxis. The recommended dose is
C. Drăghici   +5 more
semanticscholar   +1 more source

Isotretinoin induced achilles tendinopathy: Histopathological and biomechanical evaluation on rats

open access: yesActa Orthopaedica et Traumatologica Turcica, 2018
Objective: The aim of the present study was to evaluate histopathological and biomechanical effects of isotretinoin on Achilles tendon. Materials & methods: Sixteen rats were divided into two groups including the control group (n = 8) and isotretinoin ...
Ozan Beytemür   +5 more
doaj   +1 more source

Skeletal Side Effects of Systemic Isotretinoin Treatment: Do They Depend on Age, Gender, Treatment Duration, Daily Dose and Isotretinoin-Naiveness?

open access: yesDermatology Practical & Conceptual, 2023
Introduction: Systemic isotretinoin is the most effective treatment modality in acne vulgaris; however, both patients and physicians hesitate to use it due its side effects.
Defne Özkoca   +5 more
doaj   +1 more source

Isotretinoin-associated exercise-induced anaphylaxis in a patient with birch pollinosis and soybean sensitization: case presentation and literature review

open access: yesAllergy, Asthma & Clinical Immunology, 2021
Background Peanut and soybean allergies are listed as contraindication in the package leaflet of isotretinoin, a widely used treatment of acne vulgaris.
Anna Bamidis, Silke C. Hofmann
doaj   +1 more source

Low‐dose isotretinoin versus minocycline in the treatment of rosacea

open access: yesDermatologic Therapy, 2021
Rosacea is a common inflammatory facial skin condition affecting the adult population. Its papulopustular subtype is mainly treated pharmacologically by topical and oral antibiotics.
A. Shemer   +5 more
semanticscholar   +1 more source

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