ISOTRETINOIN FOR TREATING ACNE VULGARIS [PDF]
, 2021 Acne vulgaris (AV) occurs in more than 80% of dermatological cases in adolescents and young adults and affects the quality of life. Oral isotretinoin, a metabolite product of vitamin A, is well-known to be the most effective treatment for severe ...
SITOHANG, IRMA BERNADETTE S.
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Isotretinoin Revisited: Pluripotent Effects on Human Sebaceous Gland Cells [PDF]
, 2006 Nelson et al. confirmed the previously described antiproliferative effect of isotretinoin on human sebocytes. They attributed a portion of this decrease to cell cycle arrest and detected sebocyte apoptosis, which was not recapitulated by alitretinoin or ...
Zouboulis, Christos C.
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Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions
Cancer Nexus, EarlyView.ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley +1 more source
Analysis of common oral and topical dermatologic medication price variation by source [PDF]
, 2020 Online coupon retailers and pharmacies are popular sites that patients can access discounted medications when compared to cash prices. These sources are especially important for those patients without insurance.
Boyko, Alexander, Smith, Gideon P
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Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]
, 2014 Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
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Laboratory tests in patients treated with isotretinoin: occurrence of liver and muscle abnormalities and failure of AST and ALT to predict liver abnormality. [PDF]
, 2017 Current laboratory monitoring may not be optimal. A retrospective chart review was performed on thelaboratory results of 246 patients who were treated with isotretinoin for acne over a 9-year period.
Grimes, Lorraine R. +2 more
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Treatment Survival in Patients With Hidradenitis Suppurativa
JEADV Clinical Practice, EarlyView.ABSTRACT Background Despite the existence of therapeutic approaches, effective management of hidradenitis suppurativa (HS) remains elusive in many cases. In addition, most of the current studies focus on treatment response in a cross‐sectional analysis of patients, and therefore a proper study analysing different treatment strategies longitudinally in ...
Lea Schulte‐Oestrich +3 more
wiley +1 more source
Mycosis Fungoides in Paediatric Patients: A Real‐Life Retrospective Study
JEADV Clinical Practice, EarlyView.Our study represents the largest cohort of children with MF worldwide, providing relevant evidence supporting phototherapy as first‐line treatment, with an overall remission rate of 36.36%. Both topical and systemic therapy also showed favourable outcomes.
Mariana de la Vega +2 more
wiley +1 more source
Isotretinoin exposure during pregnancy: A population-based study in the Netherlands [PDF]
, 2014 Objective: To estimate isotretinoin exposure in Dutch pregnant women despite the implemented pregnancy prevention programme (PPP) and second, to analyse the occurrence of adverse fetal or neonatal outcomes in these isotretinoin exposed pregnancies.Design:
Herings, R.M.C. (Ron) +6 more
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Liposomal delivery of hydrophobic RAMBAs provides good bioavailability and significant enhancement of retinoic acid signalling in neuroblastoma tumour cells [PDF]
, 2020 Retinoid treatment is employed during residual disease treatment in neuroblastoma, where the aim is to induce neural differentiation or death in tumour cells.
Bilip, Maja +11 more
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