Results 41 to 50 of about 197,507 (284)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Isotype: international picture language

open access: yes, 2010
Curated and designed exhibition at the Victoria & Albert Museum. This display, in collaboration with the University of Reading, traces the story of Isotype over four decades, from its invention in 1920s Vienna to its flourishing in postwar ...
Burke, Christopher   +2 more
core   +6 more sources

Machine learning predictions of IgG1 and IgG4 self-association and high-concentration solution properties

open access: yesmAbs
To meet the widespread demand for subcutaneous delivery of antibody therapeutics, candidates with low viscosity, high solubility, and/or low aggregation propensity in concentrated formulations must be identified.
Na-Young Kwon   +7 more
doaj   +1 more source

The immunopathology of human schistosomiasis-III: immunoglobulin isotype profiles and response to praziquantel

open access: yesMemorias do Instituto Oswaldo Cruz, 1996
Immunoglobulin (Ig) isotype (IgG, IgG1, IgG2, IgG3, IgG4, IgM, IgD and IgE) levels were investigated, both pre- and post-treatment with praziquantel (PZQ), in 43 adults and children chronically infected with Schistosoma mansoni , by means of a two-site ...
Romelia M Ramírez   +4 more
doaj   +1 more source

The linguistic status of Isotype

open access: yes, 2011
It is ironic that Otto Neurath, one of those responsible for the ‘linguistic turn’ in philosophy of the twentieth century, should have been concerned during the last twenty years of his life with developing a ‘pictorial language’.
Burke, Christopher
core   +6 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

‘Isotype, visuelle Hilfsmittel und die Kolonien’

open access: yes
A concise account of Isotype, visual aids, and the colonies, including discussion of Otto Neurath's arguments in favour of visual aids and their contribution to visual education in colonial territories; the activities of Wolfgang Foges, Adprint, and ...
Kindel, Eric
core   +3 more sources

Features of the photo-electric characteristics of photoelectric converter of structures

open access: yesТехнологія та конструювання в електронній апаратурі, 2007
The peculiarities of photoelectric characteristics of converter structures based on the isotype n-GaAs/n-GaInAs heterojunction with Ag potential barriers have been investigated.
A. V. Karimov   +5 more
doaj  

Immunoglobulin A Isotype of Antiphospholipid Antibodies Does Not Provide Added Value for the Diagnosis of Antiphospholipid Syndrome in a Chinese Population

open access: yesFrontiers in Immunology, 2020
ObjectiveAntiphospholipid syndrome (APS) is characterized by the presence of anti-phospholipid (aPL) antibodies. However, the relationship between the immunoglobulin (Ig) A isotype of aPL positivity and its clinical utility in APS diagnosis is ...
Chaojun Hu   +13 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy