Results 21 to 30 of about 188,123 (308)

Determining immunoglobulin-specific B cell receptor repertoire of murine splenocytes by next-generation sequencing

STAR Protocols, 2022
Summary: High-throughput antibody repertoire analysis via next-generation sequencing is a key method in understanding humoral immunity. Errors introduced during library preparation and sequencing can be corrected with molecular amplification ...
Anja Werner, Simon Schäfer, Nina Gleußner, Falk Nimmerjahn, Thomas H. Winkler   +4 more
doaj   +1 more source

Monoclonal Antibodies and Toxins—A Perspective on Function and Isotype

Toxins, 2012
Antibody therapy remains the only effective treatment for toxin-mediated diseases. The development of hybridoma technology has allowed the isolation of monoclonal antibodies (mAbs) with high specificity and defined properties, and numerous mAbs have been
Siu-Kei Chow, Arturo Casadevall
doaj   +1 more source

Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4 [PDF]

, 2010
Schistosoma haematobium antigen recognition profiles of the human isotypes IgA, IgE, IgG1 and IgG4 were compared by image analysis of western blots. Adult worm antigens separated by 2-dimensional gel electrophoresis were probed with pooled sera from ...
Midzi, N., Maizels, R M, Burchmore, R., Y. HARCUS, Mduluza, T., R. M. MAIZELS, Harcus, Y, Turner, C.M.R., R. BURCHMORE, C. M. TURNER, Mutapi, F, Midzi, N, Mutapi, F., Maizels, R.M., Turner, C M, Maizels, RM, N. MIDZI, Harcus, Y., Bourke, C., F. MUTAPI, T. MDULUZA, Turner, CM, Maizels, R. M., Bourke, C, Turner, C. M., Mduluza, T, Burchmore, R.J.S., Burchmore, R, C. BOURKE   +28 more
core   +1 more source

Historical H1N1 Influenza Virus Imprinting Increases Vaccine Protection by Influencing the Activity and Sustained Production of Antibodies Elicited at Vaccination in Ferrets

Vaccines, 2019
Influenza virus imprinting is now understood to significantly influence the immune responses and clinical outcome of influenza virus infections that occur later in life.
Magen E. Francis, Mara McNeil, Nicholas J. Dawe, Mary K. Foley, Morgan L. King, Ted M. Ross, Alyson A. Kelvin   +6 more
doaj   +1 more source

Proteome and transcriptome analysis reveals tubulin isotype switching in paclitaxel-treated esophageal cancer

ESMO Gastrointestinal Oncology
Background: Despite combination therapies, less than half of patients with resectable esophageal cancer (EC) survive beyond 5 years. Previous studies, primarily using transcriptomics, revealed high plasticity in these cancer cells.
L.M. Veen, A.P. van der Zalm, D. Blangé, P. Manoukian, M. van Mourik, R.R. de Goeij-de Haas, S.R. Piersma, T.V. Pham, C.R. Jimenez, S.L. Meijer, H.W. van Laarhoven, M.F. Bijlsma   +11 more
doaj   +1 more source

Therapeutic Antibodies: What Have We Learnt from Targeting CD20 and Where Are We Going?

Frontiers in Immunology, 2017
Therapeutic monoclonal antibodies (mAbs) have become one of the fastest growing classes of drugs in recent years and are approved for the treatment of a wide range of indications, from cancer to autoimmune disease.
Michael J. E. Marshall, Richard J. Stopforth, Mark S. Cragg   +2 more
doaj   +1 more source

Isotype specific ELISAs to detect antibodies against swine vesicular disease virus and their use in epidemiology

, 2002
Isotype specific ELISAs to detect antibodies against swine vesicular disease, which may help to estimate the moment of infection, were developed and validated on sera from pigs experimentally infected with four different isolates of swine vesicular ...
Dekker, A., Hemert-Kluitenberg, F., van, Terpstra, C., Baars-Lorist, C.A., van Hemert-Kluitenberg, F.   +4 more
core   +1 more source

Aspergillus fumigatus binding IgA and IgG1 are increased in bronchoalveolar lavage fluid of horses with neutrophilic asthma

Frontiers in Immunology
IntroductionEquine asthma (EA) is a common lower airway disease in horses, but whether its pathogenesis is allergic is ambiguous. Extrinsic stimuli like hay dust induce acute exacerbation of clinical signs and sustained local neutrophilic inflammation in
Maria-Christin Jentsch, Aline Keilhaue, Bettina Wagner, Claudio Rhyner, Claudio Rhyner, Sabrina Lübke, Mariam Karagulyan, Corinna Arnold, Katharina L. Lohmann, Christiane L. Schnabel   +9 more
doaj   +1 more source

Antibody and isotype information.

, 2017
Antibody and isotype information.
Zhilin Chen (291363), Aysha Tayab (3826015), Jessica Pudwell (3826012), Patricia D. A. Lima (707898), Malia S. Q. Murphy (800163), B. Anne Croy (109241), Graeme N. Smith (627562)   +6 more
core   +1 more source

Isotype knice subgroups of global Warfield groups [PDF]

, 2006
summary:If $H$ is an isotype knice subgroup of a global Warfield group $G$, we introduce the notion of a $k$-subgroup to obtain various necessary and sufficient conditions on the quotient group $G/H$ in order for $H$ itself to be a global Warfield group.
Ullery, William, Megibben, Charles
core   +1 more source