Results 121 to 130 of about 12,790 (182)

Isoxazoles

2008
Isoxazoles, benzisoxazoles, isoxazolines, and isoxazolidines are classes of heterocyclic compounds having a remarkable number of applications and are very versatile building blocks in organic synthesis. The major developments on the chemistry of these heterocycles reported in the literature from 1996 to 2006 are reviewed.
GIOMI, DONATELLA, CORDERO, FRANCA MARIA, MACHETTI, FABRIZIO   +2 more
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Isoxazole

Isoxazole is a versatile five-membered heterocyclic compound that has attracted significant attention due to its diverse medicinal chemistry and material science applications. This chapter provides a comprehensive overview of synthetic methodologies for preparing isoxazole derivatives, including traditional approaches such as cyclization reactions and ...
Popat Mohite, Savita Tauro, Aarati Pawar
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Isoxazoles

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Isoxazoles I: Protonation of Isoxazole Derivatives in Aqueous Sulfuric Acid

Journal of Pharmaceutical Sciences, 1973
The protonation of 3-amino-5-methylisoxazole, 5-amino-3,4-dimethylisoxazole, sulfamethoxazole (N-sulfanilamido-5-methyl-3-isoxazole), and sulfisoxazole (N-sulfanilamido-3,4-dimethyl-5-isoxazole) in aqueous sulfuric acid was studied. The pKSH+ and log SH+/S or log SH2+2/SH+ values were determined by UV spectrophotometry.
R H, Manzo, M M, De Bertorello
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Synthesis of Isoxazole- and Oxazole-4-carboxylic Acids Derivatives by Controlled Isoxazole-Azirine-Isoxazole/Oxazole Isomerization

The Journal of Organic Chemistry, 2019
The first synthesis of isoxazole-4-carboxylic acid derivatives by domino isoxazole-isoxazole isomerization is reported. Fe(II)-catalyzed isomerization of 4-acyl-5-methoxy-/5-aminoisoxazoles (dioxane, 105 °C) leads to the formation of isoxazole-4-carboxylic esters and amides in good yields. 4-Formyl-5-methoxyisoxazoles give methyl oxazole-4-carboxylates
Anna V. Serebryannikova, Ekaterina E. Galenko, Mikhail S. Novikov, Alexander F. Khlebnikov   +3 more
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An Intercalating Isoxazole

Acta Crystallographica Section C Crystal Structure Communications, 1996
The title compound, ethyl 3-(9-anthryl)-5-methyl-4-isoxazolecarboxylate, C 21 H 17 NO 3 , possesses two planar ring systems that lie at 80° from coplanarity. The bond linking the two ring systems is 1.489 (3) A, indicating only partial conjugation between the two ring systems.
M. D. Mosher, N. R. Natale, A. Vij
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Studies in isoxazole chemistry. IV. Isoxazoles via isoxazolines

Canadian Journal of Chemistry, 1970
4- or 5-Chloro- or cyanoisoxazoles, 5-chloromethylisoxazoles, and 5-methylisoxazoles were made by the 1,3-dipolar cycloaddition of nitrile oxides to α-halogeno- or α-alkoxyolefins. In the case of cis- and trans-1,2-dichloroethylene, (5a and b) the intermediate cis- and trans-4,5-dichloroisoxalines (6a and b) were isolated.
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Developing Isoxazole as a Native Photo‐Cross‐Linker for Photoaffinity Labeling and Chemoproteomics

Angewandte Chemie - International Edition, 2022
Ke Cheng, Nan Ma, Hongyan Sun
exaly  

Application, Reactivity and Synthesis of Isoxazole Derivatives

Mini-Reviews in Organic Chemistry, 2021
Pramod Kulkarni, Pravin Mhaske
exaly  

Isoxazole/Isoxazoline Skeleton in the Structural Modification of Natural Products: A Review

Pharmaceuticals, 2023
Pan Xinhui
exaly