Results 101 to 110 of about 24,259 (231)

TRPV1 agonist, capsaicin, induces axon outgrowth after injury via Ca2+/PKA signaling [PDF]

open access: yes, 2018
Preconditioning nerve injuries activate a pro-regenerative program that enhances axon regeneration for most classes of sensory neurons. However, nociceptive sensory neurons and central nervous system neurons regenerate poorly.
DiAntonio, Aaron   +4 more
core   +2 more sources

MPTP-induced degeneration: interference with glutamatergic toxicity [PDF]

open access: yes, 1994
Parkinson's disease (PD) is characterised by the progressive degeneration of nigrostriatal dopamine (DA) neurons resulting in the major symptoms of akinesia and rigidity.
Lange, Klaus W.   +3 more
core  

Synthesis of Curcumin Derivatives and Analysis of Their Antitumor Effects in Triple Negative Breast Cancer (TNBC) Cell Lines [PDF]

open access: yes, 2019
We analyzed antitumor effects of a series of curcumin analogues. Some of them were obtained by reaction of substitution involving the two phenolic OH groups of curcumin while the analogues with a substituent at C-4 was prepared following an original ...
Barattucci A   +5 more
core   +1 more source

Crystal structure of ethyl 3-(4-chlorophenyl)-5-[(E)-2-(dimethylamino)ethenyl]-1,2-oxazole-4-carboxylate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C16H17ClN2O3, two molecules, A and B, with different conformations, comprise the asymmetric unit. In molecule A, the C=O group of the ester points away from the benzene ring [C—C—C=O = −170.8 (3)°], whereas in molecule B, it points
Ilya Efimov   +2 more
doaj   +1 more source

Ferrate(VI) oxidation of endocrine disruptors and antimicrobials in water [PDF]

open access: yes, 2014
Author name used in this publication: X. Z.
Doong, RA, Graham, N, Li, XZ, Sharma, VK
core   +1 more source

Computational psychiatry: a Rosetta Stone linking the brain to mental illness. [PDF]

open access: yes, 2014
PCF is supported by the Bernard Wolfe Health Neuroscience Fund and the Wellcome Trust. This work was carried out within the Wellcome- and MRC-funded Behavioural and Clinical Neuroscience Institute and the Cambridge and Peterborough NHS Foundation Trust ...
Corlett, Philip R, Fletcher, Paul C
core   +2 more sources

4-[4-(4-Fluorophenyl)-1,2-oxazol-5-yl]pyridine

open access: yesIUCrData
The title compound, C14H9FN2O, crystallizes in the monoclinic space group P21/c. The dihedral angles between the central isoxazole ring and the 4-fluorophenyl and pyridine rings are 37.51 (10) and 12.11 (15)°, respectively.
Pierre Koch, Dieter Schollmeyer
doaj   +1 more source

Combined experimental and theoretical studies of regio- and stereoselectivity in reactions of β-isoxazolyl- and β-imidazolyl enamines with nitrile oxides

open access: yesBeilstein Journal of Organic Chemistry, 2016
Reactions of β-azolyl enamines and nitrile oxides were studied by both experimental and theoretical methods. (E)-β-(4-Nitroimidazol-5-yl), (5-nitroimidazol-4-yl) and isoxazol-5-yl enamines smoothly react regioselectively at room temperature in dioxane ...
Ilya V. Efimov   +10 more
doaj   +1 more source

Design and Synthesis of New A2B Adenosine Receptor Antagonists [PDF]

open access: yes, 2009
Starting from chemical structure of N-benzo-[1,3]dioxol-5-yl-2-[5-(2,6dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-1-methyl-1H-pyrazol3-yloxy]-acetamide, MRE2029F20* various structural modifications were realized to afford a new series of A2B ...
BARALDI, Stefania
core  

Fe(II)/Et3N-Relay-catalyzed domino reaction of isoxazoles with imidazolium salts in the synthesis of methyl 4-imidazolylpyrrole-2-carboxylates, its ylide and betaine derivatives

open access: yesBeilstein Journal of Organic Chemistry, 2015
A simple approach was developed for the synthesis of methyl 4-imidazolylpyrrole-2-carboxylates from easily available compounds, 5-methoxyisoxazoles and phenacylimidazolium salts under hybrid Fe(II)/Et3N relay catalysis.
Ekaterina E. Galenko   +4 more
doaj   +1 more source

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