Results 81 to 90 of about 17,613 (213)

Theoretical Study of Thermal Decomposition Mechanisms of Isoxazole

, 1997
Density functional theory and ab initio calculations were carried out to investigate two probable unimolecular decomposition channels of isoxazole. The calculated structural parameters, dipole moment, and vibrational frequencies of isoxazole are in good ...
Zhou, Xuefeng, Liu, Ruifeng, Higgins, James, Ruifeng Liu, James Higgins, Xuefeng Zhou   +5 more
core   +1 more source

An Easy Entry to Sugar Isoxazole Derivatives Via Michael Addition/1,3-Dipolar Cycloaddition Reactions

We report a novel approach for isoxazole- or/and thioether-linked glycoconjugates whic are based on sequential Michael addition - 1,3-dipolar ...
Lugiņina, Jevgeņija, Beļakovs, Sergejs, Turks, Māris, Rjabovs, Vitālijs   +3 more
core  

4-[4-(4-Fluorophenyl)-1,2-oxazol-5-yl]pyridine

IUCrData
The title compound, C14H9FN2O, crystallizes in the monoclinic space group P21/c. The dihedral angles between the central isoxazole ring and the 4-fluorophenyl and pyridine rings are 37.51 (10) and 12.11 (15)°, respectively.
Pierre Koch, Dieter Schollmeyer
doaj   +1 more source

A facile one-pot synthesis of N α-urethane protected 3-amino alkyl isoxazole-5-carboxylic acids and their utility for the preparation of isoxazole-linked peptidomimetics

, 2011
Cu(I) catalyzed 3+2 cycloaddition of in situ generated N α-Fmoc/Boc/Z-protected amino alkyl nitrile oxide with propiolic acid has led to a new class of 3,5-disubstituted isoxazole-bearing amino acid derivatives.
Vasantha, B., Sureshbabu, V.V., Chennakrishnareddy, G., Narendra, N.   +3 more
core   +1 more source

Combined experimental and theoretical studies of regio- and stereoselectivity in reactions of β-isoxazolyl- and β-imidazolyl enamines with nitrile oxides

Beilstein Journal of Organic Chemistry, 2016
Reactions of β-azolyl enamines and nitrile oxides were studied by both experimental and theoretical methods. (E)-β-(4-Nitroimidazol-5-yl), (5-nitroimidazol-4-yl) and isoxazol-5-yl enamines smoothly react regioselectively at room temperature in dioxane ...
Ilya V. Efimov, Marsel Z. Shafikov, Nikolai A. Beliaev, Natalia N. Volkova, Tetyana V. Beryozkina, Wim Dehaen, Zhijin Fan, Viktoria V. Grishko, Gert Lubec, Pavel A. Slepukhin, Vasiliy A. Bakulev   +10 more
doaj   +1 more source

Targeting hematological malignancies with isoxazole derivatives [PDF]

Compounds with a heterocyclic isoxazole ring are well known for their diverse biologic activities encompassing antimicrobial, antipsychotic, immunosuppressive, antidiabetic and anticancer effects.
Majirská, M, Diniz, C, Vojtek, M, Pilátová, MB, Kudlicková, Z   +4 more
core   +1 more source

Synthesis of Isoxazole Glycohybrids

We report a novel approach to isoxazole- or/and thioether-amine-linked ...
Lugiņina, Jevgeņija, Turks, Māris, Rjabovs, Vitālijs   +2 more
core  

Synthesis and anti-nociceptive potential of isoxazole carboxamide derivatives

, 2019
Background Isoxazole is an important pharmacophore in medicinal chemistry with a wide range of pharmacological activities. The present study deals with the synthesis and evaluation of antinociceptive potential of nine novel 3-substituted-isoxazole-4 ...
Hajira Bibi, Muzaffar Abbas, Humaira Nadeem, Muazzam Arif   +3 more
core   +1 more source

Solid-Phase Synthesis of Novel Heterocycles Containing Thiohydantoin and Isoxazole Rings

, 2016
Solid-Phase Synthesis of Novel Heterocycles Containing Thiohydantoin and Isoxazole ...
Mark J. Kurth (1328874), Kyung-Ho Park (770569)   +1 more
core   +1 more source

Alkaloid-Based Isoxazolylureas: Synthesis and Effect in Combination with Anticancer Drugs on C6 Rat Glioma Model Cells

Molecules
Alkaloid-based urea derivatives were produced with high yield through the reaction of anabasine and cytisine with isoxazolylphenylcarbamates in boiling benzene. Their antitumor activity, in combination with the commonly used five anticancer drugs, namely
Gulim K. Mukusheva, Roza I. Jalmakhanbetova, Altynay Zh. Shaibek, Manshuk S. Nurmaganbetova, Aigerym R. Zhasymbekova, Oralgazy A. Nurkenov, Ekaterina A. Akishina, Irina A. Kolesnik, Evgenij A. Dikusar, Tatiana I. Terpinskaya, Vladimir A. Kulchitsky, Vladimir I. Potkin, Alexander L. Pushkarchuk, Dmitry A. Lyakhov, Dominik L. Michels   +14 more
doaj   +1 more source