Results 61 to 70 of about 12,790 (182)

Crystal structure of (5-chloro-2-hydroxyphenyl)(3-methylisoxazolo[5,4-b]pyridin-5-yl)methanone

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C14H9ClN2O3, the fused pyridine and isoxazole rings are approximately planar, making a dihedral angle of 1.14 (16)°. The molecule is twisted with the benzene ring and the mean plane through the fused pyridine-isoxazole ring system ...
Rajamani Raja, Nataraj Poomathi, Paramasivam T. Perumal, A. SubbiahPandi   +3 more
doaj   +1 more source

1,3′-Dimethyl-2-oxo-6′-phenyl-7′H-spiro[indoline-3,4′-isoxazolo[5,4-b]pyridine]-5′-carbonitrile

IUCrData
The title compound, C22H16N4O2, crystallizes in the monoclinic space group P21/c with two independent molecules, A and B, in the asymmetric unit. The isoxazole ring is inclined to the pyridine ring system, the indoline ring, and the phenyl ring by 8.00 ...
S. Logalakshmi, Panneerselvam Yuvaraj, Dhruba Jyoti Boruah, R. Raja, G. Puthilibai   +4 more
doaj   +1 more source

Crystal structure of ethyl 3-(4-chlorophenyl)-5-[(E)-2-(dimethylamino)ethenyl]-1,2-oxazole-4-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C16H17ClN2O3, two molecules, A and B, with different conformations, comprise the asymmetric unit. In molecule A, the C=O group of the ester points away from the benzene ring [C—C—C=O = −170.8 (3)°], whereas in molecule B, it points
Ilya Efimov, Pavel Slepukhin, Vasiliy Bakulev   +2 more
doaj   +1 more source

4-[4-(4-Fluorophenyl)-1,2-oxazol-5-yl]pyridine

IUCrData
The title compound, C14H9FN2O, crystallizes in the monoclinic space group P21/c. The dihedral angles between the central isoxazole ring and the 4-fluorophenyl and pyridine rings are 37.51 (10) and 12.11 (15)°, respectively.
Pierre Koch, Dieter Schollmeyer
doaj   +1 more source

Combined experimental and theoretical studies of regio- and stereoselectivity in reactions of β-isoxazolyl- and β-imidazolyl enamines with nitrile oxides

Beilstein Journal of Organic Chemistry, 2016
Reactions of β-azolyl enamines and nitrile oxides were studied by both experimental and theoretical methods. (E)-β-(4-Nitroimidazol-5-yl), (5-nitroimidazol-4-yl) and isoxazol-5-yl enamines smoothly react regioselectively at room temperature in dioxane ...
Ilya V. Efimov, Marsel Z. Shafikov, Nikolai A. Beliaev, Natalia N. Volkova, Tetyana V. Beryozkina, Wim Dehaen, Zhijin Fan, Viktoria V. Grishko, Gert Lubec, Pavel A. Slepukhin, Vasiliy A. Bakulev   +10 more
doaj   +1 more source

Alkaloid-Based Isoxazolylureas: Synthesis and Effect in Combination with Anticancer Drugs on C6 Rat Glioma Model Cells

Molecules
Alkaloid-based urea derivatives were produced with high yield through the reaction of anabasine and cytisine with isoxazolylphenylcarbamates in boiling benzene. Their antitumor activity, in combination with the commonly used five anticancer drugs, namely
Gulim K. Mukusheva, Roza I. Jalmakhanbetova, Altynay Zh. Shaibek, Manshuk S. Nurmaganbetova, Aigerym R. Zhasymbekova, Oralgazy A. Nurkenov, Ekaterina A. Akishina, Irina A. Kolesnik, Evgenij A. Dikusar, Tatiana I. Terpinskaya, Vladimir A. Kulchitsky, Vladimir I. Potkin, Alexander L. Pushkarchuk, Dmitry A. Lyakhov, Dominik L. Michels   +14 more
doaj   +1 more source

New Quinazolin-4(3H)-One Derivatives Incorporating Isoxazole Moiety as Antioxidant Agents: Synthesis, Structural Characterization, and Theoretical DFT Mechanistic Study

Pharmaceuticals
Background: This research centers on the development and spectroscopic characterization of new quinazolin-4(3H)-one-isoxazole derivatives (5a–e). The aim was to investigate the regioselectivity of the 1,3-dipolar cycloaddition involving arylnitriloxides ...
Yassine Rhazi, Riham Sghyar, Noemi Deak, Bouchra Es-Sounni, Bouchra Rossafi, Albert Soran, Mustapha Laghmari, Azize Arzine, Asmae Nakkabi, Khalil Hammani, Samir Chtita, Mohammed M. Alanazi, Gabriela Nemes, Mohamed El. Yazidi   +13 more
doaj   +1 more source

tert-Butyl [(4-fluoro-3-isopropoxyisoxazol-5-yl)methyl](phenylsulfonyl)carbamate

IUCrData
The title compound, C18H23FN2O6S, a new derivative of a fluoroisoxazole containing sulfonamide functionality has been structurally characterized. The C—S—N—Cipr and C—S—N—Ccarb (ipr = 3-isopropoxyisoxazole, carb = carbamate) torsion angles are 111.1 (3)°
Mohd Abdul Fatah Abdul Manan, David B. Cordes   +1 more
doaj   +1 more source

Isoxazole Derivative Induces Apoptosis-like Death and Autophagy through Oxidative Stress in <i>Leishmania amazonensis</i>. [PDF]

ACS Omega
Kawano Bakoshi AB, Beltrame Machado RR, Pianoski KE, Mendes De Souza Melo S, Andreia Rosa F, Silva Lautenschlager SO, Ueda-Nakamura T, Nakamura CV, Lazarin-Bidóia D.   +8 more
europepmc   +1 more source

Isoxazole-Thiazole Hybrids: Synthesis, Structural Characterisation, Carbonic Anhydrase Inhibition, and Molecular Docking Studies. [PDF]

Molecules
Berber N, Türkeri ÖN, Başoğlu F, Çıkrıkcı K, Ergün A, Gencer N.   +5 more
europepmc   +1 more source