Results 71 to 80 of about 17,613 (213)
Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors
, 2016 The identification of a novel series of small molecule BET inhibitors is described. Using crystallographic binding modes of an amino-isoxazole fragment and known BET inhibitors, a structure-based drug design effort lead to a novel isoxazole azepine ...
Brian K. Albrecht (1417963) +23 more
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I. Über das Amid der Acetessigsäure. II. Beiträge zur Kenntnis der Isoxazole
, 1903 I. ÜBER DAS AMID DER ACETESSIGSÄURE. II. BEITRÄGE ZUR KENNTNIS DER ISOXAZOLE I. Über das Amid der Acetessigsäure. II. Beiträge zur Kenntnis der Isoxazole ([1]) Binding ( - ) Title page ([1]) Dedication ([3]) I.
Meyer, Konrad
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, 2016 A collection of 91 3-(arylthiomethyl)isoxazole-4,5-dicarboxamides was prepared starting from dimethyl 3-(chloromethyl)isoxazole-4,5-dicarboxylate.
Gui J. Yu (1330485) +6 more
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Crystal structure of (5-chloro-2-hydroxyphenyl)(3-methylisoxazolo[5,4-b]pyridin-5-yl)methanone
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C14H9ClN2O3, the fused pyridine and isoxazole rings are approximately planar, making a dihedral angle of 1.14 (16)°. The molecule is twisted with the benzene ring and the mean plane through the fused pyridine-isoxazole ring system ...
Rajamani Raja +3 more
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Therapeutic Potential of Isoxazole–(Iso)oxazole Hybrids: Three Decades of Research
Heterocyclic compounds are a common subject in the field of medicinal chemistry due to their numerous pharmaceutical applications. Among these, nitrogen- and oxygen-containing five-membered heterocyclic rings, namely oxazole and isoxazole, are ...
Marcin Mączyński +2 more
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3,5-Bis(4-fluorophenyl)isoxazole
, 2012 In the crystal structure of the title compound, C15H9F2NO, the complete molecule is generated by a crystallographic twofold rotation axis and the O and N atoms of the central isoxazole ring are statistically disordered with equal site occupancies.
S. Samshuddin +4 more
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, 2020 Isoxazole and pyrazole derivatives have a wide range of biological activity and they are of great interest to medicinal chemist. In this study, the synthesis and characterization of a series of novel hybrid molecules containing pyrazole and isoxazole ...
Budak, Yakup +3 more
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1,3′-Dimethyl-2-oxo-6′-phenyl-7′H-spiro[indoline-3,4′-isoxazolo[5,4-b]pyridine]-5′-carbonitrile
IUCrDataThe title compound, C22H16N4O2, crystallizes in the monoclinic space group P21/c with two independent molecules, A and B, in the asymmetric unit. The isoxazole ring is inclined to the pyridine ring system, the indoline ring, and the phenyl ring by 8.00 ...
S. Logalakshmi +4 more
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Synthesis of Carbohydrate-Isoxazole Conjugates
Herein we report the synthesis of galactose and gulose derivatives that contain isoxazole moiety at C(3 ...
Lugiņina, Jevgeņija +3 more
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Use of isoxazole derivatives as cyclooxygenase inhibitors
, 2010 isoxazole derivatives development as cyclooxygenase ...
TACCONELLI S +6 more
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