Results 91 to 100 of about 24,259 (231)
Psychedelics, entactogens and psychoplastogens for depression and related disorders
British Journal of Pharmacology, EarlyView.Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley +1 more source
Long-term potentiation in bone – a role for glutamate in strain-induced cellular memory? [PDF]
, 2003 Background The adaptive response of bone cells to mechanical strain is a primary determinant of skeletal architecture and bone mass. In vivo mechanical loading induces new bone formation and increases bone mineral density whereas disuse, immobilisation ...
Genever Paul G, Spencer Gary J
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Acta Physiologica, Volume 242, Issue 6, June 2026.ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner +6 more
wiley +1 more source
PKM and the maintenance of memory. [PDF]
, 2013 How can memories outlast the molecules from which they are made? Answers to this fundamental question have been slow coming but are now emerging.
Glanzman, David L
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Analysis of products from the pyrolysis of plastics recovered from the commercial scale recycling of waste electrical and electronic equipment [PDF]
, 2007 Three plastic fractions from a commercial waste electrical and electronic equipment (WEEE) processing plant were collected and investigated for the possibility of recycling them by batch pyrolysis. The first plastic was from equipment containing cathode
Hall, W.J., Williams, P.T.
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Studies on Oxasteroids. I. Synthesis of 3-Cyano-3-methylchroman-4-one. [PDF]
, 1968 Condensation of chroman-4-one with ethyl formate in the presence of sodium methoxide gave 3-hydroxymethylenechroman-4-one (II). Reaction of II with hydroxylamine hydrochloride, followed isomerization by potassium t-butoxide gave IV.
Honjo, Yozo, Moriwake, Tosio
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Psychiatry and Clinical Neurosciences, Volume 80, Issue 5, Page 367-373, May 2026.Psychiatric and neurological disorders severely compromised patients' quality of life. Despite their urgent needs, the development of diagnostics and therapeutics based on the biological basis has made only little progress. This is due to limited evidence on the biological basis of these disorders in humans. Synapses are fundamental structural units of
Mai Hatano, Hiroki Abe, Takuya Takahashi
wiley +1 more source
Characterization of Phosphorylation Sites on the Glutamate Receptor 4 Subunit of the AMPA Receptors [PDF]
, 1999 Recent studies have suggested that protein phosphorylation of glutamate receptors may play an important role in synaptic transmission. Specifically, the phosphorylation of AMPA receptors has been implicated in cellular models of synaptic plasticity.
Carvalho, Ana Luísa +2 more
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ChemPhysChem, Volume 27, Issue 7, 14 April 2026.The development of effective strategies for the detoxification of organophosphorus (OP) nerve agents has evolved from the early mechanistic studies of François Terrier and collaborators, who first elucidated the exceptional nucleophilicity of α‐effect species such as oximes and hydroxamates, to the modern design of supramolecular and material‐based ...
Pedro Rodríguez‐Dafonte
wiley +1 more source
InCl3-assisted synthesis and cytotoxic studies of some novel heteroaryl thiazoles [PDF]
, 2013 Heteroaryl thiazoles were synthesized by the Hantzsch reaction of various α-bromoketones with aryl thioureas using InCl3 as a catalyst in a shorter reaction time. The synthesized compds.
Boggavarapu Chand, S.G. +5 more
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