Results 51 to 60 of about 17,613 (213)

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source

Beiträge zur Kenntnis der Isoxazole

, 1902
BEITRÄGE ZUR KENNTNIS DER ISOXAZOLE Beiträge zur Kenntnis der Isoxazole ([1]) Binding ( - ) Title page ([1]) Dedication ([3]) Section ([5]) Einleitung. ([6]) Experimenteller Teil.
Mumm, Otto
core   +1 more source

N‐methyl‐D‐aspartate receptor antagonists for controlling pain in dogs

Journal of Small Animal Practice, EarlyView.
This is a mini review published by the World Small Animal Veterinary Association's Pain Committee. This article provides an assessment of the scientific evidence of N‐methyl‐d‐aspartate receptor antagonists for controlling pain in dogs while identifying current knowledge gaps.
P. W. Kronen, B. D. X. Lascelles, B. P. Monteiro, J. C. Murrell, S. A. Robertson, P. V. Steagall, B. Wright   +6 more
wiley   +1 more source

Sterically Facilitated Intramolecular Nucleophilic NMe₂ Group Substitution in the Synthesis of Fused Isoxazoles: Theoretical Study

Molecules, 2020
The influence of steric repulsion between the NMe2 group and a second ortho-(peri-)substituent in the series of 1-dimethylaminonaphthalene and N,N-dimethylanilene ortho-oximes on the ease of the NMe2 group’s intramolecular nucleophilic substitution is ...
Alexander S. Antonov, Elena Yu Tupikina, Valerii V. Karpov, Valeriia V. Mulloyarova, Victor G. Bardakov   +4 more
doaj   +1 more source

Quantitative Pharmacodynamic Analysis of Trimethoprim‐Sulfonamide Combination Activity Against Staphylococcus pseudintermedius

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Trimethoprim (TMP)‐sulfonamide combinations are widely used in veterinary medicine, yet the quantitative nature of their pharmacodynamic interaction remains incompletely characterised. This study investigated the interaction between TMP and sulfamethoxazole (SMX), sulfadiazine (SDZ) and sulfadimethoxine (SDMX) against two Staphylococcus ...
Andrew Mead, Alexis Viel, Marine Boulanger, Gudrun Overesch, Carl Ekstrand, Pierre‐Louis Toutain, Aude A. Ferran, Ludovic Pelligand   +7 more
wiley   +1 more source

The preparation of an isoxazole derivative of 4-hydroxycoumarin

, 1998
A method for preparation of an isoxazole derivative of 4-hydroxycoumarin, 3-phenyl-5-(4-hydroxy-3-coumarinyl)-isoxazole has been described. The reaction sequence includes addition of bromine to 3-cinnamoyl-4-hydroxycoumarin, and the subsequent treatment ...
Krstic, L, Sukdolak, S, Stefanović, Milutin, Solujic, S, Sladić, Dušan   +4 more
core   +4 more sources

Isoxazole Alters Metabolites and Gene Expression, Decreasing Proliferation and Promoting a Neuroendocrine Phenotype in β‑Cells

, 2016
Novel strategies are needed to modulate β-cell differentiation and function as potential β-cell replacement or restorative therapies for diabetes. We previously demonstrated that small molecules based on the isoxazole scaffold drive neuroendocrine ...
Svetlana Earnest (1418557), Claudia Savoia (1418551), Jay W. Schneider (1418569), Zhimin Huang (147312), Chonlarat Wichaidit (1418560), Elhadji M. Dioum (1418566), Michele R. Hutchison (420537), Melanie H. Cobb (1418563), Michael A. Kalwat (1418572), Kathleen McGlynn (1418554)   +9 more
core   +2 more sources

Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches

Analysis &Sensing, Volume 6, Issue 6, November 2026.
The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi, Jacob T. Theismann, Michael A. Johnson   +2 more
wiley   +1 more source

Beiträge zur Kenntnis der Isoxazole

, 1900
BEITRÄGE ZUR KENNTNIS DER ISOXAZOLE Beiträge zur Kenntnis der Isoxazole ([1]) Binding ( - ) Title page ([1]) Dedication ([3]) Section ([5]) Einleitung. ([7]) Experimenteller Teil. (18) I.
Thomaschewski, Paul
core   +1 more source

A concise synthesis of isoxazole-based side chain of Micafungin

, 2019
A concise synthesis of key isoxazole-based side chain of Micafungin, an USFDA approved anti-fungal agent, has been delineated. The route design notably involves a one pot regioselective isoxazole construction from the corresponding aryl aldehyde and ...
Ismail Hussain (6840758), Srinivas Oruganti (1617001), Saikat Sen (1617007), Venkataramanarao Rao (2044960), Pallavi Rao (2265352)   +4 more
core   +1 more source