Results 21 to 30 of about 16,147 (226)
Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds
Molecules, 2023 The biological significance of benzopyran-4-ones as cytotoxic agents against multi-drug resistant cancer cell lines and isoxazoles as anti-inflammatory agents in cellular assays prompted us to design and synthesize their hybrid compounds and explore ...
Shilpi Gupta +5 more
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Isoxazole-based pharmaceuticals.
, 2023 A series of new derivatives based on sulfamethoxazole were designed and synthesized in this study. The structures of the new compounds were confirmed based on a comprehensive characterization of spectral data by applied IR and 1H as well as 13C NMR ...
Vilma Petrikaitė (321635) +4 more
core +1 more source
Heterocyclic Communications, 2021 The present study aimed to design and synthesize a series of phenyl-isoxazole-carboxamide derivatives and investigate their antitumor and antioxidant activities. The in vitro cytotoxic evaluation was conducted using the MTS assay against four cancer cell
Hawash Mohammed +7 more
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Methyl 4-amino-3-methoxyisoxazole-5-carboxylate
IUCrData, 2023 The title compound, C6H8N2O4, a new derivative of isoxazole, has been synthesized and structurally characterized. The crystal structure shows the molecule to be almost planar (r.m.s.
Mohd Abdul Fatah Abdul Manan +2 more
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Molecules, 2022 Isoxazole derivatives are significant enough due to their wide range of pharmacological and therapeutic activities. The purpose of the current study is to use computational, in vitro, in vivo, and extensive molecular approaches to examine the possible ...
Sidra Razzaq +7 more
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Berichte der deutschen chemischen Gesellschaft (A and B Series), 1921 n ...
Meisenheimer, Jakob, Weibezahn, Karl
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Journal of Advanced Pharmaceutical Technology & Research, 2023 Lung cancer is the most common malignancy worldwide, with approximately 1.8 million new cases yearly. Cytotoxic drugs are frequently used in cancer treatment.
Duha E Taha +2 more
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(3-Methyl-3a,4,7,7a-tetrahydro-5H-4,7-methanoisoxazolo[4,5-d][1,2]oxazin-5-yl)(phenyl)methanone
Acta Crystallographica Section E, 2014 The title compound, C14H14N2O3, is the exo isomer with a syn arrangement of two O atoms in the isoxazole and oxazine rings. The dihedral angle between the isoxazole and phenyl rings is 60.38 (4)°.
Alan J. Lough +2 more
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Isoxazolyl-Derived 1,4-Dihydroazolo[5,1-c][1,2,4]Triazines: Synthesis and Photochemical Properties
Molecules, 2023 New fluorescent dyes containing an assembled 1,4-dihydroazolo[5,1-c][1,2,4]triazine (DAT) core and an isoxazole ring were synthesized through a reaction between diazopyrazole or diazoimidazoles and isoxazolyl-derived enamines in mild conditions.
Elena V. Sadchikova +4 more
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Synthesis and characterization of selected fused isoxazole and pyrazole derivatives and their antimicrobial activity [PDF]
Journal of the Serbian Chemical Society, 2009 New potent antibacterials, fused isoxazole and pyrazole derivatives, were synthesized using 5,5-dimethylcyclohexane-1,3-dione (1) and 3-[(4-chlorobenzylidene) amino]-2-thioxoimidazolidin-4-one (2) as synthons.
Dabholkar Vijay V., Ansari Faisal Y.
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