Results 261 to 270 of about 19,238 (306)

Synthesis of new isoxazole derivatives

Russian Journal of Organic Chemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
N. N. Yusubov, M. M. Kantaeva, V. M. Ismailov, I. A. Mamedov   +3 more
openaire   +3 more sources

Studies in isoxazole chemistry. IV. Isoxazoles via isoxazolines

Canadian Journal of Chemistry, 1970
4- or 5-Chloro- or cyanoisoxazoles, 5-chloromethylisoxazoles, and 5-methylisoxazoles were made by the 1,3-dipolar cycloaddition of nitrile oxides to α-halogeno- or α-alkoxyolefins. In the case of cis- and trans-1,2-dichloroethylene, (5a and b) the intermediate cis- and trans-4,5-dichloroisoxalines (6a and b) were isolated.
openaire   +2 more sources

Iterative Assembly of Nitrile Oxides and Ynamides: Synthesis of Isoxazoles and Pyrroles.

Journal of Organic Chemistry, 2019
Described is an iterative assembly of nitrile oxides and ynamides for the synthesis of isoxazoles and pyrroles. The nitrile oxides could undergo Cu(I)-free cyclization with terminal ynamides for accessing isoxazoles, which could engage in another ...
Changwei Chen, Sunliang Cui
semanticscholar   +1 more source

Synthesis of Spiro[indole-3,5'-isoxazoles] with Anticancer Activity via a Formal [4 + 1]-Spirocyclization of Nitroalkenes to Indoles.

Journal of Organic Chemistry, 2019
An acid-assisted [4 + 1]-cycloaddition of indoles with nitrostyrenes affords 4' H-spiro[indole-3,5'-isoxazoles] in a diastereomerically pure form. Several of these spirocyclic molecules exhibit promising anticancer activity by reducing viability and ...
Alexander V Aksenov, D. Aksenov, Nikolai A. Arutiunov, N. Aksenov, E. Aleksandrova, Zhenze Zhao, Liqin Du, A. Kornienko, M. Rubin   +8 more
semanticscholar   +1 more source

Four-Component Reactions for the Synthesis of Perfluoroalkyl Isoxazoles

ACS Catalysis, 2019
A four-component strategy for the synthesis of the isoxazole skeleton is developed. The approach achieves the synthesis of perfluoroalkyl isoxazoles by using simple perfluoroalkyl reagents.
Yuanjin Chen, Liangkui Li, Xiao-qiang He, Zhiping Li   +3 more
semanticscholar   +1 more source

An asymmetric isoxazole annulation

Journal of Heterocyclic Chemistry, 1988
AbstractAn Asymmetric isoxazole annulation proceeds from the (S)‐O‐methoxyphenylalaninol imine of (RS)‐2‐phen‐ylpropionaldehyde (3). Deprotonation, quenching with 4‐chloromethyl‐3,5‐dimethylisoxazole, and hydrolysis produced isoxazolylaldehyde (5), whose structure was confirmed by single crystal X‐ray diffractometry. The absolute configuration of (‐)‐5
Ludwig Schlicksupp, Brian E. Marron, Nicholas R. Natale   +2 more
openaire   +3 more sources

An Efficient Synthesis of Isoxazoles and Isoxazolines [PDF]

HETEROCYCLES, 1985
AbstractDurch Umsetzung der, Hydroxamsäurechloride (III) mit Dipolarophilen wie (II), (IV) u.ä.
P. Caldirola, M. De Amici, C. De Micheli, P. Pevarello   +3 more
openaire   +2 more sources

Synthesis of 4-Sulfenyl Isoxazoles through AlCl3-Mediated Electrophilic Cyclization and Sulfenylation of 2-Alkyn-1-one O-Methyloximes.

Journal of Organic Chemistry, 2019
An efficient method for the synthesis of 4-sulfenyl isoxazoles has been developed via AlCl3-mediated electrophilic cyclization/sulfenylation of 2-alkyn-1-one O-methyloximes.
Wenchao Gao, Yu-Fei Cheng, Hong‐Hong Chang, Xing Li, Wenlong Wei, Peng Yang   +5 more
semanticscholar   +1 more source

Electronic structure of isoxazole

Bulletin of the Academy of Sciences, USSR Division of Chemical Science, 1966
1. The scheme of the levels, the molecular diagram, and the indices of the reactivity of isoxazole were calculated by the simple LCAO MO method using the Huckel approximation. 2. Within the framework of the given approximation it was shown that for radical and nucleophilic substitution reactions the reactivity of the different positions ...
A. V. Tutkevich, Alexander A. Bagaturyants, D. A. Bochvar   +2 more
openaire   +2 more sources

Synthesis of Isoxazole Triflones

European Journal of Organic Chemistry, 2012
AbstractThe first practical synthesis of isoxazole triflones 3 (4‐trifluoromethanesulfonylisoxazoles, 4‐triflylisoxazoles) has been achieved by an operationally simple procedure consisting of the reaction between readily available α‐triflyl ketones 4 and imidoyl chlorides 5 in the presence of triethylamine.
Hiroyuki Kawai, Etsuko Tokunaga, Norio Shibata, Yutaka Sugita   +3 more
openaire   +3 more sources