Results 101 to 110 of about 8,655 (241)

Suspected neurological toxicity after oral application of fluralaner (Bravecto®) in a Kooikerhondje dog

BMC Veterinary Research, 2019
Background Although the new isoxazoline drug fluralaner (Bravecto®) is generally well tolerated in dogs, adverse drug reactions involving neurological dysfunction occurred in individual dogs.
Daniela Gaens, Christoph Rummel, Martin Schmidt, Melanie Hamann, Joachim Geyer   +4 more
doaj   +1 more source

Synthesis, Antimicrobial Evaluation, and Docking Study of Some New Isoxazoline Derivatives Derived from Chalcones

Journal of the Turkish Chemical Society, Section A: Chemistry
New 2-Isoxazoline derivatives containing furan moieties were synthesized from chalcones as starting materials, followed by antimicrobial activity. Chalcones were synthesized by reacting p-methoxy acetophenone or 3,4-(methylenedioxy)acetophenone with ...
Abdulkadir Mohammed Noori Jassim, Inas Salim, Ahmed Mutanabbi Abdula   +2 more
doaj   +1 more source

2-Methoxy-4-[5-(2-oxo-1,3-dioxolan-4-yl)-4,5-dihydroisoxazol-3-yl]phenyl 4-n-decyloxybenzoate

Molbank
This study addresses the synthesis of a new liquid crystalline compound featuring a 3,5-disubstituted isoxazoline and a 1,3-dioxolan-2-one ring, and renewable aromatic building blocks derived from vanilin and benzoic acid.
Itamar Luís Gonçalves, Aloir Antonio Merlo, Bruna Thatise Batistel, Leonardo Rossner Wbatuba, Henrique de Aguiar Mello   +4 more
doaj   +1 more source

Nitroimidazoles XIII. Synthesis of Substituted (1-Methyl-5-Nitro-2-Imidazolyl) Isoxazoles [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1998
The beta0diketone derivatives of nitroimidazole were synthesized from the reaction of magnesium salt of beta-ketoaccids 3 with imidazolide 4. The raction of beta-diketones with hydroxylamine hydrochloride afforded either the isoxazoles or the 5-hydroxyl ...
Abbas Shafiee, Mohammad ALi Ebrahimzadeh
doaj  

Silicon-Tethered 1,3-Dipolar Cycloaddition of 4-Hydroxy-2-isoxazoline 2-Oxides

, 1996
Silicon-tethered 1,3-dipolar cycloaddition of 4-hydroxy-2-isoxazoline 2 ...
Landuzzi, Andrea, Righi, Paolo, Rosini, Goffredo, Marotta, Emanuela   +3 more
core   +1 more source

Gold Redox Catalysis for Cyclization/Arylation of Allylic Oximes: Synthesis of Isoxazoline Derivatives

Chemical Communications, 2019
Base-assisted diazonium activation has been employed to promote gold (I)/(III) redox catalysis toward allylic oxime cyclization/aryl coupling. Functional isoxazolines were prepared with good to excellent yields, while the alternative photoactivation ...
A. Jimoh, S. Hosseyni, Xiao-Han Ye, L. Wojtas, Yong Hu, Xiaodong Shi   +5 more
semanticscholar   +1 more source

Uso do fluralaner no tratamento da demodicidose canina juvenil generalizada: relato de caso

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
RESUMO O objetivo do presente trabalho foi relatar a eficácia do fluralaner no tratamento da demodicidose juvenil generalizada canina. Dois caninos, apresentando dois e três meses de idade, com diagnóstico clínico e parasitológico de demodicidose ...
J.A.B. Bezerra, I.R.S. Cardoso, R.T.G.A. Rodrigues, K.D. Filgueira   +3 more
doaj   +1 more source

Synthesis and biological activities of novel isoxazoline-linked pseudodisaccharide derivatives

, 2012
A series of novel isoxazoline linked pseudodisaccharide derivatives were regiospecifically synthesized by 1,3-dipolar cycloaddition of alpha-allyl-C-glycopyranosides and sugar-derived nitrile oxides with good yields.
Wang, Kerang, Li, Xiaoliu, Liu, Ming, Kerang Wang, Wang, Wei, Yin, Qingmei, Chao Wei, Wang, Enkai, Qingmei Yin, Hua Chen, Zhang, Pingzhu, Zhang, Jinchao, Pingzhu Zhang, Ming Liu, Jinchao Zhang, Xiaoliu Li, Chen, Hua, Wei, Chao, Wei Wang, Enkai Wang   +19 more
core   +1 more source

5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity

, 2005
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline has been synthesized by reacting benzonitrile oxide with the enolate ion of methyl vinyl ketone. From 5-hydroxy-5-vinyl-2-isoxazoline, 5-vinylisoxazole was then quantitatively obtained by dehydration–aromatization
DI NUNNO L, VITALE, PAOLA, Di Nunno, Leonardo, SCILIMATI, Antonio   +3 more
core   +1 more source

Silicon-Tethered 1,3-Dipolar Cycloaddition of 4-Hydroxy-2-isoxazoline 2-Oxides

, 2016
Silicon-Tethered 1,3-Dipolar Cycloaddition of 4-Hydroxy-2-isoxazoline 2 ...
Emanuela Marotta (611756), Paolo Righi (611755), Andrea Landuzzi (2997837), Goffredo Rosini (2499802)   +3 more
core   +1 more source