Results 101 to 110 of about 8,235 (246)

Synthesis, Antimicrobial Evaluation, and Docking Study of Some New Isoxazoline Derivatives Derived from Chalcones

Journal of the Turkish Chemical Society, Section A: Chemistry
New 2-Isoxazoline derivatives containing furan moieties were synthesized from chalcones as starting materials, followed by antimicrobial activity. Chalcones were synthesized by reacting p-methoxy acetophenone or 3,4-(methylenedioxy)acetophenone with ...
Abdulkadir Mohammed Noori Jassim, Inas Salim, Ahmed Mutanabbi Abdula   +2 more
doaj   +1 more source

Suspected neurological toxicity after oral application of fluralaner (Bravecto®) in a Kooikerhondje dog

BMC Veterinary Research, 2019
Background Although the new isoxazoline drug fluralaner (Bravecto®) is generally well tolerated in dogs, adverse drug reactions involving neurological dysfunction occurred in individual dogs.
Daniela Gaens, Christoph Rummel, Martin Schmidt, Melanie Hamann, Joachim Geyer   +4 more
doaj   +1 more source

Synthesis and discovery of the putative cognitive enhancer BRS-015: effect on glutamatergic transmission and synaptic plasticity

, 2015
This thesis is concerned with the discovery of a novel heterocyclic compound – BRS-015, its synthesis and an analysis of its effects on excitatory synaptic transmission at a major pathway in the brain.
Szulc, BR
core  

Enantioselective Intramolecular Oxidative Aminocarbonylation of Alkenylureas Catalyzed by Palladium−Spiro Bis(isoxazoline) Complexes

, 2016
An enantioselective synthesis of tetrahydropyrrolo[1,2-c]pyrimidine-1,3-diones via a palladium-catalyzed intramolecular oxidative aminocarbonylation is described.
Hiroaki Sasai (1764031), Shinobu Takizawa (1764043), Kiyotaka Onitsuka (1468588), Kazuhiro Takenaka (2186842), Minoru Hatanaka (1592692), Tetsuya Tsujihara (2330581), Toshio Shinohara (2330584)   +6 more
core   +3 more sources

Nitroimidazoles XIII. Synthesis of Substituted (1-Methyl-5-Nitro-2-Imidazolyl) Isoxazoles [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1998
The beta0diketone derivatives of nitroimidazole were synthesized from the reaction of magnesium salt of beta-ketoaccids 3 with imidazolide 4. The raction of beta-diketones with hydroxylamine hydrochloride afforded either the isoxazoles or the 5-hydroxyl ...
Abbas Shafiee, Mohammad ALi Ebrahimzadeh
doaj  

Synthesis of New N-Phthalimide Substituted Tricyclic Imide Containing Isoxazoline and Bispiro Functional Group as Possible Anti-cancer Agents

Journal of the Turkish Chemical Society, Section A: Chemistry, 2017
[3+2]-Cycloaddition reactions of N-phthalimide substituted tricyclic imide were studied to synthesize their isoxazoline and bispiro derivatives in excellent yields.
Ömer Tahir Günkara, Nuket Ocal
doaj   +1 more source

Catalytic asymmetric syntheses of isoxazoline-N-oxides under phase-transfer conditions. [PDF]

, 2011
Catalytic asymmetric syntheses of various isoxazoline-N-oxides have been accomplished by asymmetric phase-transfer conjugate addition of bromomalonate to nitroolefins and subsequent ring-closing O ...
Taichi Kano, Sunhwa Song, Maruoka, Keiji, Song, Sunhwa, Keiji Maruoka, Akihiro Yamamoto, Kano, Taichi, Yamamoto, Akihiro   +7 more
core   +1 more source

Gold Redox Catalysis for Cyclization/Arylation of Allylic Oximes: Synthesis of Isoxazoline Derivatives

Chemical Communications, 2019
Base-assisted diazonium activation has been employed to promote gold (I)/(III) redox catalysis toward allylic oxime cyclization/aryl coupling. Functional isoxazolines were prepared with good to excellent yields, while the alternative photoactivation ...
A. A. Jimoh, S. Hosseyni, X. Ye, L. Wojtas, Yong Hu, Xiaodong Shi   +5 more
semanticscholar   +1 more source

5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity

, 2005
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline has been synthesized by reacting benzonitrile oxide with the enolate ion of methyl vinyl ketone. From 5-hydroxy-5-vinyl-2-isoxazoline, 5-vinylisoxazole was then quantitatively obtained by dehydration–aromatization
DI NUNNO L, VITALE, PAOLA, Di Nunno, Leonardo, SCILIMATI, Antonio   +3 more
core   +1 more source

Survey of canine use and safety of isoxazoline parasiticides

Veterinary Medicine and Science, 2019
A veterinarian and pet owner survey (Project Jake) examined the use and safety of isoxazoline parasiticides given to dogs. Data were received during August 1–31, 2018 from a total of 2,751 survey responses.
V. Palmieri, W. Dodds, J. Morgan, E. Carney, H. Fritsche, J. Jeffrey, Rowan G. Bullock, J. P. Kimball   +7 more
semanticscholar   +1 more source