Results 81 to 90 of about 5,925 (227)

Syntheses of Isoxazoline-Based Amino Acids by Cycloaddition of Nitrile Oxides and Their Conversion into Highly Functionalized Bioactive Amino Acid Derivatives [PDF]

, 2012
The present account illustrates the syntheses of isoxazoline- based amino acids by the cycloaddition of 1,3-dipolar nitrile oxides to the C–C double bond of unsaturated amino acid derivatives, with focus on the regio- and stereoselectivities of the ...
Fülöp, Ferenc, Kiss, Loránd, Nonn, Melinda   +2 more
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Strategies for the control of Rhipicephalus microplus ticks in a world of conventional acaricide and macrocyclic lactone resistance [PDF]

, 2018
Infestations with the cattle tick, Rhipicephalus microplus, constitute the most important ectoparasite problem for cattle production in tropical and subtropical regions worldwide, resulting in major economic losses. The control of R.
Bhushan, Chandra, Jonsson, Nicholas N., Rodriguez-Vivas, Roger I.   +2 more
core   +1 more source

An Unexpected Formation of Spiro Isoxazoline-Dihydrofurane Compounds from Substituted Ketofurfuryl Alcohols

Molecules
Oximation of substituted ketofurfuryl alcohols in the presence of hydroxylamine hydrochloride and pyridine in ethanol as solvent led to a new class of spiro derivatives presenting a 7-methylene-1,6-dioxa-2-azaspiro [4.4] nona-2,8-diene skeleton along ...
Claire Cuyamendous, Mathieu Yves Laurent, Christine Saluzzo   +2 more
doaj   +1 more source

Synthesis, Biological Evaluation, and Molecular Docking of Tellurium‐Containing Benzothiazole Derivatives as Enzyme Inhibitors of DNA Gyrase and Dihydrofolate Reductase

BioMed Research International, Volume 2026, Issue 1, 2026.
Tellurium‐containing heterocycles represent an emerging class of organochalcogen compounds with notable redox properties and antimicrobial potential. Incorporation of tellurium into sulfur‐ and nitrogen‐containing frameworks can enhance biological activity through increased polarizability and favorable noncovalent interactions.
Olha Haleha, Valeriy Pantyo, Nataliya Korol, Elvira Danko, Mykhailo Onysko, Poorani Gurumallesh Prabu   +5 more
wiley   +1 more source

Bicyclic Pyrrolidine-Isoxazoline γ Amino Acid: A Constrained Scaffold for Stabilizing α-Turn Conformation in Isolated Peptides

Frontiers in Chemistry, 2019
Unnatural amino acids have tremendously expanded the folding possibilities of peptides and peptide mimics. While α,α-disubstituted and β-amino acids are widely studied, γ-derivatives have been less exploited.
Francesco Oliva, Raffaella Bucci, Lucia Tamborini, Stefano Pieraccini, Andrea Pinto, Sara Pellegrino   +5 more
doaj   +1 more source

Direct introduction of nitrogen and oxygen functionality with spatial control using copper catalysis. [PDF]

, 2018
Synthetic chemists have spent considerable effort optimizing the synthesis of nitrogen and oxygen containing compounds through a number of methods; however, direct introduction of N- and O-functionality remains challenging.
Fisher, David J, Limon, Luis, Read de Alaniz, Javier, Shaum, James B, Sroda, Miranda M   +4 more
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World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

Enantioselective Desymmetrization by Chiral Bifunctional H‐Bonding Organocatalysts

Chemistry – A European Journal, Volume 31, Issue 61, November 3, 2025.
Enantioselective desymmetrization has emerged as a highly efficient and conceptually elegant strategy for the construction of chiral molecules from readily available prochiral substrates. This review focuses on recent developments in organocatalytic desymmetrization reactions, with particular emphasis on approaches involving bifunctional activation ...
Michal Urban, Jan Veselý
wiley   +1 more source

Synthesis and Application of Bioactive N‐Functionalized Aziridines

Angewandte Chemie, Volume 137, Issue 44, October 27, 2025.
This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Hao Tan, Samya Samanta, Nan Qiu, Alexander Adibekian, David C. Powers   +4 more
wiley   +1 more source

Synthesis of some flurophenyl 4-oxocyclopentane[d]isoxazolines and their dioxolane derivatives [PDF]

, 2013
A number of new fluorophenyl 4-oxocyclopentane[d]isoxazolines and their dioxolane derivatives has been synthesized. The obtained substances are of the interest as the perspective biologically active compounds as well as the intermediates in total ...
Antonevich, I. P., Nesterova, S. V.
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