Results 71 to 80 of about 4,771 (210)
Sesquiterpene lactones emerge as structurally diverse anticancer scaffolds with multifaceted mechanisms of action. Their biosynthesis, chemical diversity, structure–activity relationships, semisynthetic diversification, and molecular targets are integrated to highlight therapeutic opportunities and challenges.
Kedar Nimba Chaudhari +3 more
wiley +1 more source
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline and 3-phenyl-5-vinylisoxazole: synthesis and reactivity
5-Hydroxy-3-phenyl-5-vinyl-2-isoxazoline has been synthesized by reacting benzonitrile oxide with the enolate ion of methyl vinyl ketone. From 5-hydroxy-5-vinyl-2-isoxazoline, 5-vinylisoxazole was then quantitatively obtained by dehydration–aromatization
DI NUNNO L +3 more
core +1 more source
An efficient [4 + 1] annulation between α-bromooximes and sulfur ylides via in situ generation of nitrosoalkenes under mild basic reaction conditions has been developed, providing an expeditious and scalable approach to synthesize biologically ...
Ting-Bi Hua +4 more
doaj +1 more source
Advances in Agricultural Applications of Lignans
This graphical abstract presents lignans as green alternatives to chemical pesticides and antibiotics for agriculture and veterinary use. It illustrates their applications in plant protection (antifungal, insecticidal, herbicidal, fruit preservation) and aquaculture, classifies lignan subtypes from classic to complex forms, highlights limitations like ...
Kaida Li +5 more
wiley +1 more source
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi +3 more
wiley +1 more source
The synthesis of novel imidazolyl substituted δ2-isoxazoline libraries are currently of high interest. We report here in the full details of a study leading to the synthesis and antifungal activities of 3-(-2-butyl-4-chloro-1H-imidazolyl)-substituted δ2 ...
Mantelingu, K. +4 more
core +1 more source
Unnatural amino acids have tremendously expanded the folding possibilities of peptides and peptide mimics. While α,α-disubstituted and β-amino acids are widely studied, γ-derivatives have been less exploited.
Francesco Oliva +5 more
doaj +1 more source
A greener strategy for the synthesis of some functionalized heterocycles have been developed using Sonogashira cross-coupling reaction of furfural derived isoxazolidine and isoxazoline derivatives.
Bhaskar Chakraborty, Esmita Chettri
doaj +1 more source
Heterocyclic‐Based Fungicides: Emerging Strategies for Viable Plant Disease Control
Heterocyclic compounds have attracted considerable attention because of their structural diversity, potent antifungal activity, and ability to interact with multiple fungal targets, offering broad‐spectrum protection against phytopathogens. Synthetic and semisynthetic/part‐natural scaffolds, particularly azole, quinoline, indole, cyclotryptamine, and ...
Sumit Tahlan +4 more
wiley +1 more source
A NEW PEPTIDE-BOND SURROGATE - 2-ISOXAZOLINE IN PSEUDODIPEPTIDE CHEMISTRY
The 2-isoxazoline ring has been incorporated as a new peptide bond surrogate into pseudodipeptide.
KEUM, GC +9 more
core +1 more source

