Results 51 to 60 of about 5,925 (227)

Fecal elimination of fluralaner in different carnivore species after oral administration

Frontiers in Veterinary Science
Fluralaner is a recent external parasiticide, first of a new class of drugs (isoxazoline parasiticides). It is widely used in companion animals both for its wide spectrum (fleas, ticks and other mites) but also for its ease of use (oral tablets given ...
Philippe Jacques Berny, Dalil Belhadj, Bernadette España, Alexis Lécu   +3 more
doaj   +1 more source

New isoxazolidinyl-based N-alkylethanolamines as new activators of human brain carbonic anhydrases

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Carbonic anhydrases (CAs) are widespread metalloenzymes which catalyse the reversible hydration of carbon dioxide (CO2) to bicarbonate (HCO3−) and a proton, relevant in many physiological processes. In the last few years, the involvement of CA activation
Doretta Cuffaro, Riccardo Di Leo, Lidia Ciccone, Alessio Nocentini, Claudiu T. Supuran, Elisa Nuti, Armando Rossello   +6 more
doaj   +1 more source

Susceptibility of Phthorimaea absoluta (Meyrick) (Lepidoptera: Gelechiidae) to novel and established insecticides in Brazil: resistance survey, baseline, and implications for management

Pest Management Science, EarlyView.
Baseline susceptibility of Phthorimaea absoluta to novel insecticides isocycloseram and tolfenpyrad was established in Brazil. Diagnostic doses were proposed for early resistance detection. Early tolfenpyrad tolerance and abamectin‐driven cross‐tolerance to isocycloseram via oxidases highlight cross‐resistance risks, emphasizing the need for routine ...
Vitor Quintela, Teófilo P Langa, José VCR Dantas, Marcos de Oliveira, Herbert AA Siqueira   +4 more
wiley   +1 more source

Synthesis and Reactivity of Acyclic (pentadienyl)iron(1+) Cations: Model Studies for the Preparation of the 8\u3cem\u3eE\u3c/em\u3e,10\u3cem\u3eZ\u3c/em\u3e,16\u3cem\u3eE\u3c/em\u3e,18\u3cem\u3eE\u3c/em\u3e-Tetraene Segment of Macrolactin A [PDF]

, 1999
The dicarbonyl(1,2-dimethylpentadienyl)triphenylphosphineiron(1+) cation (11) has been prepared from methyl 4-methyl-2E,4E-hexadienoate in four steps.
Donaldson, William, El-Ahl, Abdel-Aziz S, Yun, Young   +2 more
core   +1 more source

A Facile Synthesis of Some Bioactive Isoxazoline Dicarboxylic Acids via Microwave-Assisted 1,3-Dipolar Cycloaddition Reaction

Reactions
The microwave-assisted 1,3-dipolar cycloaddition reaction of several aldoximes and dimethyl-2-methylene glutarate in the presence of diacetoxyiodobenzene as an oxidant produced four new isoxazoline-derived dimethyl carboxylates.
Jessica Master, Shekiel Sydney, Harsha Rajapaske, Malek Saffiddine, Vikiana Reyes, Richard W. Denton   +5 more
doaj   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

The catalytic hydrogenation of 3-(2-fluorophenyl)- and 3-(4-fluorophenyl)-4,4-ethylenedioxycyclopenta[d]isoxazolines [PDF]

, 2016
The catalytic hydrogenation of 3-(2-fluorophenyl)- and 3-(4-fluorophenyl)-4,4-ethylenedioxycyclo-penta[d ]isoxazolines led with good yields to corresponding fluorinated β -hydroxyketones.
Antonevich, I. P., Katok, Ya. M., Nesterova, S. V.   +2 more
core  

Synthesis of 3,5-Disubstituted Isoxazoles and Isoxazolines in Deep Eutectic Solvents [PDF]

, 2015
The synthesis of different 3,5-disubstituted isoxazoles and related isoxazolines using choline chloride:urea as deep eutectic solvent (DES) in a one-pot three step reaction has been accomplished successfully. The use of highly nucleophilic functionalized
Pérez Galera, Juana María, Ramón, Diego J.   +1 more
core   +3 more sources

Δ2-ISOXAZOLINE DERIVATIVES AS ANTIMICROBIALS [PDF]

Heterocyclic Communications, 2006
The inhibitory effect of newly synthesized C- (anthranyl and biphenyl)-5-substituted-I´2-isoxazolines were characterized by IR, 1H NMR, 13C NMR and CHN anal. and evaluated for their antimicrobial activity against different strains. Strains such as Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens, Xanthomonas campestris pvs., Xanthomonas ...
Priya, B. S., Basappa, Rangappa, K. S.
openaire   +2 more sources

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl, Mies Bethäuser, Daniela Nürnberger, Stefan Oswald, Andreas Moritz, Melanie Hamann, Joachim Geyer   +6 more
wiley   +1 more source