Results 51 to 60 of about 4,771 (210)

Indoor residual spraying of distinct insecticide formulations in a household‐scale micro‐mosaic format: Feasibility and effectiveness for malaria vector control in rural Zambia

Medical and Veterinary Entomology, EarlyView.
Densities of all Anopheles species were approximately comparable across all IRS regimes. No differences observed between treatment regimes regarding species composition of the Anopheles funestus group or An. gambiae complex. This operational pilot demonstrates the practical feasibility of IRS micro‐mosaics, despite the inherent increase in deployment ...
Dingani Chinula, Kenzo Mumba, Reuben Zulu, Ketty Ndhlovu, Deogratius R. Kavishe, Neil Philip Hobbs, Samson Kiware, Thomas Reed, Busiku Hamainza, Gerry F. Killeen   +9 more
wiley   +1 more source

Silicon-Tethered 1,3-Dipolar Cycloaddition of 4-Hydroxy-2-isoxazoline 2-Oxides

, 1996
Silicon-tethered 1,3-dipolar cycloaddition of 4-hydroxy-2-isoxazoline 2 ...
Landuzzi, Andrea, Righi, Paolo, Rosini, Goffredo, Marotta, Emanuela, Emanuela Marotta, Andrea Landuzzi, Paolo Righi, Goffredo Rosini   +7 more
core   +1 more source

An Unexpected Formation of Spiro Isoxazoline-Dihydrofurane Compounds from Substituted Ketofurfuryl Alcohols

Molecules
Oximation of substituted ketofurfuryl alcohols in the presence of hydroxylamine hydrochloride and pyridine in ethanol as solvent led to a new class of spiro derivatives presenting a 7-methylene-1,6-dioxa-2-azaspiro [4.4] nona-2,8-diene skeleton along ...
Claire Cuyamendous, Mathieu Yves Laurent, Christine Saluzzo   +2 more
doaj   +1 more source

Efficacy and Field Safety of the Second‐Generation, Highly Selective JAK1 Inhibitor Atinvicitinib for the Treatment of Canine Atopic Dermatitis: A Multicentre, Blinded, Randomised, Placebo‐Controlled Clinical Trial in Client‐Owned Dogs

Veterinary Dermatology, EarlyView.
Background: Janus kinase (JAK) inhibitors alleviate pruritus and clinical signs of canine atopic dermatitis (cAD). Objective: To confirm the optimal dosing regimen of atinvicitinib, a second‐generation highly selective inhibitor of JAK1 in dogs. Conclusions and Clinical Relevance: Once‐daily atinvicitinib was safe, well‐tolerated and effective at ...
Faris Jirjis, Timothy J. Kowalski, Robin C. Lynn, Lindsey Overbey, Qi Cao, Matthew Stock, Inka Kuhlmann   +6 more
wiley   +1 more source

A study on selective transformation of norbornadiene into fluorinated cyclopentane-fused isoxazolines

Beilstein Journal of Organic Chemistry, 2021
This work presents an examination of the selective functionalization of norbornadiene through nitrile oxide 1,3-dipolar cycloaddition/ring-opening metathesis (ROM)/cross-metathesis (CM) protocols. Functionalization of commercially available norbornadiene
Zsanett Benke, Attila M. Remete, Loránd Kiss   +2 more
doaj   +1 more source

New isoxazolidinyl-based N-alkylethanolamines as new activators of human brain carbonic anhydrases

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Carbonic anhydrases (CAs) are widespread metalloenzymes which catalyse the reversible hydration of carbon dioxide (CO2) to bicarbonate (HCO3−) and a proton, relevant in many physiological processes. In the last few years, the involvement of CA activation
Doretta Cuffaro, Riccardo Di Leo, Lidia Ciccone, Alessio Nocentini, Claudiu T. Supuran, Elisa Nuti, Armando Rossello   +6 more
doaj   +1 more source

Diagnostic Performance of Immunoglobulin E Serology, Prick Test and Patch Test With Food Allergens in Dogs With Atopic Dermatitis and Adverse Food Reactions Using the Double‐Blind Placebo‐Controlled Food Challenge as Gold Standard

Veterinary Dermatology, EarlyView.
Background: In dogs with adverse food reactions (AFRs), immunoglobulin (Ig)E serology, prick test and patch test with food allergens have shown variable diagnostic performance for the identification of the offending foods, when the latter were identified using open food challenges.
Evi I. Sofou, Svetlina Aleksandrova, Elisa Samuel, Manolis Chatzis, Manolis N. Saridomichelakis   +4 more
wiley   +1 more source

Synthesis of Isoxazoline Derivatives through Boulton–Katritzky Rearrangement of 1,2,4-Oxadiazoles

, 2013
The base-induced rearrangement of 1,2,4-oxadiazoles into isoxazoline derivatives is reported. This represents the first example of a three-atom side-chain rearrangement that involves a saturated CCO side chain at C-3 of the oxadiazole.
PALUMBO PICCIONELLO, Antonio, GUARCELLO, Annalisa, BUSCEMI, Silvestre, PACE, Andrea   +3 more
core   +1 more source

Management of Eprinomectin Neurotoxicosis in Cats

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To provide a resource for managing eprinomectin neurotoxicosis in cats, emphasizing the unique aspects of this particular macrocyclic lactone. Etiology The label dose of eprinomectin‐containing parasiticides causes neurotoxicosis in P‐glycoprotein–deficient cats.
Katrina L. Mealey, Linda G. Martin, Victoria P. Kastenholz   +2 more
wiley   +1 more source

Combined experimental and theoretical studies of regio- and stereoselectivity in reactions of β-isoxazolyl- and β-imidazolyl enamines with nitrile oxides

Beilstein Journal of Organic Chemistry, 2016
Reactions of β-azolyl enamines and nitrile oxides were studied by both experimental and theoretical methods. (E)-β-(4-Nitroimidazol-5-yl), (5-nitroimidazol-4-yl) and isoxazol-5-yl enamines smoothly react regioselectively at room temperature in dioxane ...
Ilya V. Efimov, Marsel Z. Shafikov, Nikolai A. Beliaev, Natalia N. Volkova, Tetyana V. Beryozkina, Wim Dehaen, Zhijin Fan, Viktoria V. Grishko, Gert Lubec, Pavel A. Slepukhin, Vasiliy A. Bakulev   +10 more
doaj   +1 more source