Results 31 to 40 of about 4,771 (210)

Síntese e avaliação preliminar da atividade antinociceptiva de novas isoxazolil-aril-hidrazonas

Química Nova, 2011
New 2-isoxazoline aldehydes were synthesized, in good yields, from cycloadduct of the 1,3-dipolar cycloaddition reaction between endocyclic enecarbamate and carboethoxyformonitrile oxide (CEFNO). Condensation of these 2-isoxazoline aldehydes with several
Sílvio Leandro Gonçalves Bomfim Reis, Valderes Moraes de Almeida, Gleybson Correia de Almeida, Karinna Moura Boaviagem, Charles Christophe Du Barriere Mendes, Antônio Rodolfo de Faria, Alexandre José da Silva Góes, Laudelina Rodrigues Magalhães, Teresinha Gonçalves da Silva   +8 more
doaj   +1 more source

Synthesis of some 3,5-diarylisoxazoline derivatives in ionic liquids media [PDF]

Journal of the Serbian Chemical Society, 2012
Biologically active isoxazoline derivatives were efficiently synthesized in excellent yields and in less reaction time using mild, effective and environmentally friendly butylmethylimidazolium bromide as solvent and catalyst.
Safaei-Ghomi Javad, Ghasemzadeh Ali Mohammad   +1 more
doaj   +1 more source

A New Asymmetric Wacker-Type Cyclization and Tandem Cyclization Promoted by Pd(II)-Spiro Bis(isoxazoline) Catalyst

, 2016
A New Asymmetric Wacker-Type Cyclization and Tandem Cyclization Promoted by Pd(II)-Spiro Bis(isoxazoline ...
Hiroaki Sasai (1764031), Midori A. Arai (1647700), Minori Kuraishi (2984331), Takayoshi Arai (1507834)   +3 more
core   +4 more sources

Synthesis of new 5-(1H-pyrazol-4-yl)-isoxazoline derivatives. [PDF]

, 2016
This work describes new 5-(1H-pyrazol-4-yl)-isoxazoline derivatives synthesis conditions and methods of novel compounds by reductive ring opening under the reaction conditions and techniques.
Špokaitė, Jurgita,
core   +1 more source

Design and Synthesis of the First Spiro Bis(isoxazoline) Derivatives as Asymmetric Ligands

, 2016
A chiral bis(isoxazoline) ligand (SPRIX) containing a rigid spiro skeleton was designed and synthesized via a double intramolecular nitrile oxide cycloaddition.
Hiroaki Sasai (1764031), Midori A. Arai (1647700), Takayoshi Arai (1507834)   +2 more
core   +3 more sources

Kinetic Study on the Base-Catalyzed Imine-Enamine Tautomerism of a Chiral Biologically Active Isoxazoline Derivative by HPLC on Amylose Tris(3,5-dimethylphenylcarbamate) Chiral Stationary Phase

Molecules, 2023
Isoxazoline is a nitrogen- and oxygen-containing five-membered heterocyclic scaffold with diverse biological profiles such as antimicrobial, fungicidal, anticancer, antiviral, analgesic and anti-inflammatory activity.
Daniele Sadutto, Paolo Guglielmi, Simone Carradori, Daniela Secci, Roberto Cirilli   +4 more
doaj   +1 more source

Enantioselective Intramolecular Oxidative Aminocarbonylation of Alkenylureas Catalyzed by Palladium−Spiro Bis(isoxazoline) Complexes

, 2016
An enantioselective synthesis of tetrahydropyrrolo[1,2-c]pyrimidine-1,3-diones via a palladium-catalyzed intramolecular oxidative aminocarbonylation is described.
Hiroaki Sasai (1764031), Shinobu Takizawa (1764043), Kiyotaka Onitsuka (1468588), Kazuhiro Takenaka (2186842), Minoru Hatanaka (1592692), Tetsuya Tsujihara (2330581), Toshio Shinohara (2330584)   +6 more
core   +4 more sources

Discovery of a Novel Class of Acylthiourea-Containing Isoxazoline Insecticides against Plutella xylostella

Molecules, 2023
Isoxazoline structures are widely found in natural products and are rich in biological activities. This study discloses the development of a series of novel isoxazoline derivatives by introducing acylthiourea fragments to access insecticidal activity ...
Fangyi Li, Biaobiao Jiang, Yuqin Luo, Siqi He, Di Feng, Deyu Hu, Runjiang Song   +6 more
doaj   +1 more source

Formation of oxime and isoxazoline from aldehyde derivatives via one-pot synthesis [PDF]

, 2020
Isoxazolines and isoxazoles are used as intermediates to create important functional groups. They also have practical uses such as the products soretolide, an epileptic seizure medication, valdecoxib, an anti-inflammatory drug, muscimol, a GABA ...
Hirschbeck, Sarah
core  

Synthesis and Pharmacological Significance of Isoxazoline Derivatives: A Mini review

Academic Science Journal
Five-membered heterocycles, like isoxazolines, are an important class of compounds of bioorganic and pharmacological importance. They have been treated as useful intermediates for the transformation of a large number of bioactive molecules.
mohammed alwan
doaj   +1 more source