Synthesis and biological evaluation of phosphonated dihydroisoxazole nucleosides [PDF]
, 2006 Phosphonated isoxazolinyl nucleosides have been prepared via 1,3-dipolar cycloaddition reaction of nitrile oxides with corresponding vinyl or allyl nucleobases for antiviral studies.
Balestrieri, E +8 more
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One-pot asymmetric cyclocarbohydroxylation sequence for the enantioselective synthesis of functionalised cyclopentanes [PDF]
, 2010 International audienceA new method has been developed for the enantioselective synthesis of highly functionalised cyclopentanes bearing up to three stereogenic centres with very high stereoselectivity.
Bonne, Damien +4 more
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Synthesis and characterization of novel oxazines and demonstration that they specifically target cyclooxygenase 2 [PDF]
, 2015 In the present study, we used solution combustion synthesis-bismuth oxide (Bi2O3) as catalyst for the simple and efficient synthesis of 1,2-oxazine based derivatives of 6-fluoro-3-(piperidin-4-yl)benzo[d]isoxazoles, 1-arylpiperazine and carbazoles.
Baburajeev, C.P. +13 more
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Chemistry and Biology of Streptogramin A Antibiotics [PDF]
, 2007 The streptogramin A antibiotics have proven to be highly active against Gram positive bacteria, particularly methicillin-resistant Staphylococcus aureus. Members of this group of compounds are characterized by a 23-membered macrocycles containing polyene,
Ahmed, Fahim, Donaldson, William
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Novel achievements with an old metal: Copper-promoted synthesis of four-membered azacycles [PDF]
, 2014 The synthesis of four-membered azacycles is of importance because of the chemical and biological relevance of these compounds. Recent progress in copper-catalyzed reactions has been applicable to a variety of research fields, such as heterocyclic ...
Alcaide, Benito +2 more
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Synthesis and reductive cleavage of 3-(2-flurophenyl) and 3-(4-flurophenyl)-cyclopent-5-en[d]isoxazolines by raney nickel in trifluroacetic acid [PDF]
, 2013 3-Fluoro arylcycloopent-5-en[d]isoxazolines have been obtained via the 1,3-dipolar cycloaddition of cyclopentadiene to aromatic nitrile oxides. The reductive cleavage of these isoxazolines by Raney nickel in trifluoroacetic acid led to corresponding ...
Antonevich, I. P. +2 more
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Journal of the Turkish Chemical Society, Section A: ChemistryNew 2-Isoxazoline derivatives containing furan moieties were synthesized from chalcones as starting materials, followed by antimicrobial activity. Chalcones were synthesized by reacting p-methoxy acetophenone or 3,4-(methylenedioxy)acetophenone with ...
Abdulkadir Mohammed Noori Jassim +2 more
doaj +1 more source
BMC Veterinary Research, 2019 Background Although the new isoxazoline drug fluralaner (Bravecto®) is generally well tolerated in dogs, adverse drug reactions involving neurological dysfunction occurred in individual dogs.
Daniela Gaens +4 more
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Inhibition of oncogenic transcription factor REL by the natural product derivative calafianin monomer 101 induces proliferation arrest and apoptosis in human B-lymphoma cell lines [PDF]
, 2015 Increased activity of transcription factor NF-κB has been implicated in many B-cell lymphomas. We investigated effects of synthetic compound calafianin monomer (CM101) on biochemical and biological properties of NF-κB.
Chennamadhavuni, Spandan +4 more
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Evaluation of afoxolaner chewables to control flea populations in naturally infested dogs in private residences in Tampa FL, USA [PDF]
, 2015 Citation: Dryden, M. W., Smith, V., Chwala, M., Jones, E., Crevoiserat, L., McGrady, J. C., . . . Carithers, D. (2015). Evaluation of afoxolaner chewables to control flea populations in naturally infested dogs in private residences in Tampa FL, USA ...
Carithers, D. +9 more
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