Results 201 to 210 of about 8,819 (284)

Lotilaner Ophthalmic Solution, 0.25%, for the Treatment of Demodex Blepharitis. [PDF]

open access: yesHealthcare (Basel)
Davey PG   +7 more
europepmc   +1 more source

The Therapeutic Potential of Spirooxindoles in Cancer: A Focus on p53-MDM2 Modulation. [PDF]

open access: yesPharmaceuticals (Basel)
Girgis AS   +8 more
europepmc   +1 more source

2‐Isoxazolines: A Synthetic and Medicinal Overview

ChemMedChem, 2020
Isoxazolines are nitrogen‐ and oxygen‐containing five‐membered heterocyclic scaffolds with extensive biological activities. This framework can be readily obtained in good to excellent yields through 1,3‐dipolar cycloaddition between nitrones with alkynes
G. Kumar, R. Shankar
semanticscholar   +3 more sources

Rational Design of Insecticidal Isoxazolines Containing Sulfonamide or Sulfinamide Structure as Antagonists of GABA Receptors with Reduced Toxicities to Honeybee and Zebrafish.

Journal of Agricultural and Food Chemistry, 2023
To develop highly effective, nontarget organism-friendly insecticides based on the isoxazoline scaffold, we rationally designed and synthesized 25 isoxazoline derivatives containing sulfonamides and sulfinamides. Their insecticidal activities against the
Shuai Yang   +7 more
semanticscholar   +1 more source

Regioselective Cycloaddition of Alkenes with tert-butyl Nitrite: A Cascade Approach to the Formation of Δ2-Isoxazolines.

Journal of Organic Chemistry, 2023
A route for cycloaddition reaction of alkenes and tert-butyl nitrite to synthesize Δ2-isoxazolines has been developed. The overall process involves the formation of multiple chemical bonds without the use of a catalyst.
Yi Liu   +6 more
semanticscholar   +1 more source

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