Results 31 to 40 of about 1,834 (212)
Bicyclic Isoxazoline Derivatives: Synthesis and Evaluation of Biological Activity
Molecules, 2022 The application of non-planar scaffolds in drug design allows for the enlargement of the chemical space, and for the construction of molecules that have more effective target–ligand interactions or are less prone to the development of resistance.
Kseniya N. Sedenkova +11 more
doaj +1 more source
, 2021 An asymmetric synthesis of 5-halomethyl pyrazolines and isoxazolines which bear a tertiary stereocenter by catalytic halocyclization of β,γ-unsaturated hydrazones and ketoximes is described.
Xue-Qin Tu (11746894) +13 more
core +1 more source
A one-pot synthesis of 3-trifluoromethyl-2-isoxazolines from trifluoromethyl aldoxime
Beilstein Journal of Organic Chemistry, 2013 Functionalized 3-trifluoromethyl-2-isoxazolines and 3-trifluoromethylisoxazoles were easily prepared from trifluoromethyl aldoxime 2 under mild conditions by using DIB as oxidant.
Raoni S. B. Gonçalves +4 more
doaj +1 more source
Navigating Nitration Chemistry: A Practical Guide to Reagents, Mechanisms, and Selectivity
Angewandte Chemie, Volume 138, Issue 20, 11 May 2026.This review highlights key contributions of modern nitration chemistry, emphasizing sustainable mechanistic platforms and comparing the performance of both organic and inorganic reagents across aromatic, ipso‐, olefin, alkyne, and heteroatom nitration. It provides the community with a clearer, unified perspective on current advances and facilitates the
Harry Lecomte +2 more
wiley +2 more sources
, 2023 A route for cycloaddition reaction of alkenes and tert-butyl nitrite to synthesize Δ2-isoxazolines has been developed. The overall process involves the formation of multiple chemical bonds without the use of a catalyst.
Yi Liu (36759) +6 more
core +2 more sources
, 2016 Aryl acetaldoximes are reacted with allylarenes in the presence of sodium hypochlorite to give 3,5-bis(arylmethyl)-2-isoxazolines which are then converted to 1,5-diaryl-4-hydroxy-2-pentanones by a reductive hydrogenation in the presence of water.
Juha T. Pulkkinen (1656310) +1 more
core +1 more source
The Isoxazoline Route to α-Methylen Lactones. [PDF]
Tetrahedron Letters, 1983 A new route to α-methylene lactones, important structural subunits of many natural products, has been developed using the nitrile oxide derived from 2-nitroethanol.
Alan P, Kozikowski, Arun K, Ghosh
openaire +2 more sources
Synthesis and antibacterial studies of some novel isoxazoline derivatives [PDF]
Journal of the Serbian Chemical Society, 2007 A series of 3-[3-(2,4-dichloro-5-fluorophenyl)-5-(2-furyl)-4,5-dihydro-1H-pyrazol-1-yl]-5-(substituted phenyl/2-thienyl)isoxazolines (4a-j) were prepared. The structures of the isoxazoline derivatives were confirmed on the bases of elemental analysis and
TEJASKUMAR SHAH, VIKAS DESAI
doaj +3 more sources
One Step Regioselective Synthesis of 5-Aminoisoxazoles from Nitrile Oxides and α-Cyanoenamines
Molecules, 2004 The 1,3-dipolar cycloaddition of nitrile oxides to 1-cyanoenamines gives 5-aminoisoxazoles regioselectively. Moderate to good yields could be obtained depending on the method used to generate the nitrile oxides. The intermediate isoxazolines could not be
Aïcha Derdour +2 more
doaj +1 more source
Synthesis, Antimicrobial and Antioxidant Activities of 2-Isoxazoline Derivatives
Molecules, 2020 A series of derivatives of trans-3-(2,4,6-trimethoxyphenyl)4,5-dihydroisoxazolo-4,5-bis[carbonyl-(4′phenyl)thiosemicarbazide (9) and of trans-3-(2,4,6-trimethoxyphenyl)-4,5-dihydro isoxazolo-4,5-bis(aroylcarbohydrazide) (10a–c) were synthesized from ...
Asma Alshamari +4 more
doaj +1 more source