Results 41 to 50 of about 3,055 (208)

One Step Regioselective Synthesis of 5-Aminoisoxazoles from Nitrile Oxides and α-Cyanoenamines

Molecules, 2004
The 1,3-dipolar cycloaddition of nitrile oxides to 1-cyanoenamines gives 5-aminoisoxazoles regioselectively. Moderate to good yields could be obtained depending on the method used to generate the nitrile oxides. The intermediate isoxazolines could not be
Aïcha Derdour, Michel Vaultier, Amar Saad   +2 more
doaj   +1 more source

The molecular targets of ivermectin and lotilaner in the human louse Pediculus humanus humanus: New prospects for the treatment of pediculosis.

PLoS Pathogens, 2021
Control of infestation by cosmopolitan lice (Pediculus humanus) is increasingly difficult due to the transmission of parasites resistant to pediculicides.
Nicolas Lamassiaude, Berthine Toubate, Cédric Neveu, Pierre Charnet, Catherine Dupuy, Françoise Debierre-Grockiego, Isabelle Dimier-Poisson, Claude L Charvet   +7 more
doaj   +1 more source

An anomalous hydration/dehydration sequence for the mild generation of a nitrile oxide [PDF]

, 2011
A nitrile oxide containing a carbamoyl group is readily generated upon the treatment of 2-methyl-4-nitro-3-isoxazolin-5(2H)-one with water under mild reaction conditions, even in the absence of special reagents.
884, 885, 886, 887, 888, 889, 890, 891, 892, 893, Ariga, Masahiro, Hirao, Shotaro, Kiyoto, Hideyuki, Kobiro, Kazuya, Maki, Asaka, Nishiwaki, Nagatoshi, Okajima, Yoshikazu, Saigo, Kazuhiko, Sawayama, Jun, Uehara, Toshiharu   +19 more
core   +2 more sources

Synthesis, Antimicrobial and Antioxidant Activities of 2-Isoxazoline Derivatives

Molecules, 2020
A series of derivatives of trans-3-(2,4,6-trimethoxyphenyl)4,5-dihydroisoxazolo-4,5-bis[carbonyl-(4′phenyl)thiosemicarbazide (9) and of trans-3-(2,4,6-trimethoxyphenyl)-4,5-dihydro isoxazolo-4,5-bis(aroylcarbohydrazide) (10a–c) were synthesized from ...
Asma Alshamari, Mahmoud Al-Qudah, Fedaa Hamadeh, Lo’ay Al-Momani, Sultan Abu-Orabi   +4 more
doaj   +1 more source

Gold-catalyzed propargylic substitutions: Scope and synthetic developments

Beilstein Journal of Organic Chemistry, 2011
This personal account summarizes our recent developments in gold-catalyzed direct substitutions on propargylic (allylic, benzylic) alcohols, with various nucleophiles (and bi-nucleophiles) based on the σ- and/or π-acidity of gold(III) complexes ...
Olivier Debleds, Eric Gayon, Emmanuel Vrancken, Jean-Marc Campagne   +3 more
doaj   +1 more source

Recent Advancements in the Control of Cat Fleas

Insects, 2020
With the advent of imidacloprid and fipronil spot-on treatments and the oral ingestion of lufenuron, the strategies and methods to control cat fleas dramatically changed during the last 25 years.
Michael K. Rust
doaj   +1 more source

The catalytic hydrogenation of 3-(2-fluorophenyl)- and 3-(4-fluorophenyl)-4,4-ethylenedioxycyclopenta[d]isoxazolines [PDF]

, 2016
The catalytic hydrogenation of 3-(2-fluorophenyl)- and 3-(4-fluorophenyl)-4,4-ethylenedioxycyclo-penta[d ]isoxazolines led with good yields to corresponding fluorinated β -hydroxyketones.
Antonevich, I. P., Katok, Ya. M., Nesterova, S. V.   +2 more
core  

Orthogonal, metal-free surface modification by strain-promoted azide–alkyne and nitrile oxide–alkene/alkyne cycloadditions [PDF]

, 2012
In this article we present a fast and efficient methodology for biochemical surface patterning under extremely mild conditions. Micropatterned azide/benzaldoxime-surfaces were prepared by microcontact printing of a heterobifunctional cyclooctyne oxime ...
Arlinghaus, Heinrich F, Burley, Glenn A, Ravoo, Bart Jan, Rinnen, Stefan, Schulz, Christian, Singh, Ishwar, Wendeln, Christian   +6 more
core   +1 more source

Biocatalytic Synthesis of Isoxazolines Enabled by Cryptic Nitrile Oxide Formation by a Vanadium‐Dependent Chloroperoxidase

Angewandte Chemie International Edition, EarlyView.
The vanadium‐dependent haloperoxidase (VHPO) class of enzymes has been shown to catalyze cryptic nitrile oxide generation in an oxidative [3+2] cycloaddition reaction between aldoximes and alkenes to generate isoxazolines. This biotechnology has been applied to a chemoenzymatic sequence starting from aldehydes through in situ condensation with ...
Manik Sharma, Kyle F. Biegasiewicz
wiley   +1 more source

Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines

Beilstein Journal of Organic Chemistry, 2017
Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones.
Somaia Kamouka, Wesley J. Moran
doaj   +1 more source