Results 41 to 50 of about 1,834 (212)

The molecular targets of ivermectin and lotilaner in the human louse Pediculus humanus humanus: New prospects for the treatment of pediculosis.

open access: yesPLoS Pathogens, 2021
Control of infestation by cosmopolitan lice (Pediculus humanus) is increasingly difficult due to the transmission of parasites resistant to pediculicides.
Nicolas Lamassiaude   +7 more
doaj   +1 more source

A new access to spiro-isoxazolines derivatives

open access: yes, 1999
A series of spiro-isoxazolines 1a-e was prepared in an one-step procedure by treating the corresponding tricarbonyl 3a-e derivatives with hydroxylamine ...
Mioskowski, C   +3 more
core   +1 more source

Gold-catalyzed propargylic substitutions: Scope and synthetic developments

open access: yesBeilstein Journal of Organic Chemistry, 2011
This personal account summarizes our recent developments in gold-catalyzed direct substitutions on propargylic (allylic, benzylic) alcohols, with various nucleophiles (and bi-nucleophiles) based on the σ- and/or π-acidity of gold(III) complexes ...
Olivier Debleds   +3 more
doaj   +1 more source

Recent Advancements in the Control of Cat Fleas

open access: yesInsects, 2020
With the advent of imidacloprid and fipronil spot-on treatments and the oral ingestion of lufenuron, the strategies and methods to control cat fleas dramatically changed during the last 25 years.
Michael K. Rust
doaj   +1 more source

Synthesis and reactions of 3-unsubstituted 2-isoxazolines [PDF]

open access: yes, 2011
2-Isoxazolines are five-membered heterocyclic compounds that serve as versatile synthetic intermediates in organic chemistry. A number of important functional groups, including 1,3-hydroxycarbonyl compounds, β-hydroxynitriles, 1,3-diamines and α,β ...
Pohjakallio, Antti
core  

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer   +6 more
wiley   +1 more source

Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines

open access: yesBeilstein Journal of Organic Chemistry, 2017
Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones.
Somaia Kamouka, Wesley J. Moran
doaj   +1 more source

Steroid [16, 17-c]isoxazoline

open access: yesChemical and Pharmaceutical Bulletin, 1964
5'-Methyl-5α-androstano[16, 17-c]isoxazolin-3β-ol (Va) and 5'-methylandrost-5-eno[16, 17-c]isoxazolin-3β-ol (Vb), were obtained by treatment of 3β, 20α-dihydroxy-5α-pregnan-16-one 3-acetate 16-oxime (IIIa) or 3β, 20α-dihydroxypregn-5-en-16-one 3-acetate 16-oxime (IIIb) with tosyl chloride in pyridine followed by alkaline hydrolysis. Oxidation of Va and
Noguchi, Shunsaku   +2 more
openaire   +3 more sources

Synthesis of 2‐Aza‐Bicyclo[4.3.0]nonane Derivatives Related to the Camporidines via Intramolecular [3+2]‐Cycloaddition

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The intramolecular nitrile oxide olefin [3 + 2]‐cycloaddition offers a reliable entry toward 2‐aza‐bicyclo[4.3.0]‐nonanes, a substructure found in several bioactive piperidine alkaloids. The required oxime precursors were prepared in non‐racemic form by Ir‐catalyzed asymmetric allylation and ring‐closing metathesis.
Alicia Köcher   +5 more
wiley   +1 more source

Crystal structure of 5-(4-tert-butoxyphenyl)-3-(4-n-octyloxyphenyl)-4,5-dihydroisoxazole

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2019
The molecule of the title compound, C27H37NO3, was prepared by [3 + 2] 1,3-dipolar cycloaddition of 4-n-octylphenylnitrile oxide and 4-tert-butoxystyrene, the latter compound being a very useful intermediate to the synthesis of liquid-crystalline ...
Eric S. Sales   +2 more
doaj   +1 more source

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