Results 11 to 20 of about 34,079 (294)
Frontiers in Medicine, 2021 Itch and worry about itch are predominant symptoms in atopic dermatitis (AD). Mindfulness refers to paying attention in a certain way, non-judgementally and on purpose. In patients with chronic pain, which shares several similarities with chronic itch, a
Kjell Lüßmann +6 more
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Nature Communications, 2020 The role of gastrin related peptide (GRP+) neurons in itch is debated. Here, the authors generate a conditional knock-in mouse to label and manipulate GRP expressing DRG neurons and investigate their role in itch and nociception.
Devin M. Barry +11 more
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Current and Emerging Therapies for Chronic Spontaneous Urticaria: A Narrative Review
Dermatology and Therapy, 2023 Chronic spontaneous urticaria (CSU) is a condition in which wheals, angioedema, and pruritus occur spontaneously and recurrently for at least 6 weeks. The etiology of this disease is partially dependent on production of autoantibodies that activate and ...
Gil Yosipovitch +2 more
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A spinal neural circuitry for converting touch to itch sensation
Nature Communications, 2020 Light touch can sometimes induce unpleasant itch sensation but the neural correlates of this conversion are not well studied. Here, the authors provide evidence that Tac2 expressing spinal interneurons are connected to gastrin-releasing peptide receptor (
Sihan Chen +11 more
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Acta Dermato-Venereologica, 2022 Chronic itch can severely affect quality of life. Patients report that their chronic itch can be exacerbated by exposure to warm conditions (“warmth hyperknesis”).
Daniele Riccio +2 more
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Cells, 2020 Neurologic insults as varied as inflammation, stroke, and fibromyalgia elicit neuropathic pain and itch. Noxious sensation results when aberrantly increased afferent signaling reaches percept-forming cortical neurons and can occur due to increased sensory signaling, decreased inhibitory signaling, or a combination of both processes.
James Meixiong +2 more
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Attentional Bias Modification Training for Itch: A Proof-of-Principle Study in Healthy Individuals
Frontiers in Medicine, 2021 Itch draws our attention to allow imposing action against bodily harm (e.g., remove insects). At the same time, itch is found to interfere with ongoing tasks and daily life goals.
Antoinette I. M. van Laarhoven +10 more
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Neuron, 2010 The description of itch (formally known as pruritus) as an "unpleasant sensation that elicits the desire or reflex to scratch" (Ikoma et al., 2006) is immediately familiar. Research in the field of pruritoception has added to our understanding of this area of sensory neurobiology as it pertains to both normal and pathological conditions. In particular,
Kush N. Patel +2 more
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Attentional Bias Towards Visual Itch and Pain Stimuli in Itch- and Pain-free Individuals?
Acta Dermato-Venereologica, 2020 Itch and pain are important attention-demanding sensations that allow adaptive responses to potential bodily harm. An attentional bias towards itch and pain stimuli, i.e.
Jennifer M. Becker +6 more
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Sensory TRP channels contribute differentially to skin inflammation and persistent itch
Nature Communications, 2017 Allergic contact dermatitis is associated both with persistent itch and inflammation, but it is not known if these are mediated by shared signaling pathways.
Jing Feng +12 more
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