Results 21 to 30 of about 77,640 (305)

Predictive factors of quality of life in chronic pruritus patients: A cross-sectional studyCapsule Summary

open access: yesJAAD International, 2023
Background: Chronic pruritus severely impacts the quality of life (QoL) of patients. Due to its multifactorial nature, the presence of factors that can predict itch-specific QoL needs comprehensive exploration.
Siri Choragudi, BS   +2 more
doaj   +1 more source

Attentional Bias Modification Training for Itch: A Proof-of-Principle Study in Healthy Individuals

open access: yesFrontiers in Medicine, 2021
Itch draws our attention to allow imposing action against bodily harm (e.g., remove insects). At the same time, itch is found to interfere with ongoing tasks and daily life goals.
Antoinette I. M. van Laarhoven   +10 more
doaj   +1 more source

Mindfulness as Predictor of Itch Catastrophizing in Patients With Atopic Dermatitis: Results of a Cross-Sectional Questionnaire Study

open access: yesFrontiers in Medicine, 2021
Itch and worry about itch are predominant symptoms in atopic dermatitis (AD). Mindfulness refers to paying attention in a certain way, non-judgementally and on purpose. In patients with chronic pain, which shares several similarities with chronic itch, a
Kjell Lüßmann   +6 more
doaj   +1 more source

Mild Skin Heating Evokes Warmth Hyperknesis Selectively for Histaminergic and Serotoninergic Itch in Humans

open access: yesActa Dermato-Venereologica, 2022
Chronic itch can severely affect quality of life. Patients report that their chronic itch can be exacerbated by exposure to warm conditions (“warmth hyperknesis”).
Daniele Riccio   +2 more
doaj   +1 more source

Transient Receptor Potential Channels and Itch

open access: yesInternational Journal of Molecular Sciences, 2022
Transient Receptor Potential (TRP) channels are multifunctional sensory molecules that are abundant in the skin and are involved in the sensory pathways of itch, pain, and inflammation.
O. Mahmoud   +2 more
semanticscholar   +1 more source

Pain and itch coding mechanisms of polymodal sensory neurons

open access: yesCell Reports, 2023
Summary: Pain and itch coding mechanisms in polymodal sensory neurons remain elusive. MrgprD+ neurons represent a major polymodal population and mediate both mechanical pain and nonhistaminergic itch. Here, we show that chemogenetic activation of MrgprD+
Changxiong Guo   +10 more
doaj   +1 more source

An Altered Skin and Gut Microbiota Are Involved in the Modulation of Itch in Atopic Dermatitis

open access: yesCells, 2022
Skin and gut microbiota play an important role in the pathogenesis of atopic dermatitis (AD). An alteration of the microbiota diversity modulates the development and course of AD, e.g., decreased microbiome diversity correlates with disease severity ...
C. Moniaga, M. Tominaga, K. Takamori
semanticscholar   +1 more source

The prelimbic cortex regulates itch processing by controlling attentional bias

open access: yesiScience, 2023
Summary: Itch is a complex and unpleasant sensory experience. Recent studies have begun to investigate the neural mechanisms underlying the modulation of sensory and emotional components of itch in the brain.
Guang-Yan Wu   +11 more
doaj   +1 more source

Itch: epidemiology, clinical presentation, and diagnostic workup.

open access: yesJournal of American Academy of Dermatology, 2021
Itch, or pruritus, is the uncomfortable sensation underlying the desire to scratch. Itch is a very common complaint in the general population that can result from dermatologic, systemic (e.g. renal, hepatobiliary, endocrine), paraneoplastic, neuropathic,
Y. Roh   +3 more
semanticscholar   +1 more source

Interleukin-33-activated neuropeptide CGRP-producing memory Th2 cells cooperate with somatosensory neurons to induce conjunctival itch.

open access: yesImmunity, 2022
Allergic conjunctivitis is a chronic inflammatory disease that is characterized by severe itch in the conjunctiva, but how neuro-immune interactions shape the pathogenesis of severe itch remains unclear.
Mikiko Okano   +11 more
semanticscholar   +1 more source

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