Results 1 to 10 of about 50,912 (262)

Anthelmintic Resistance in Ancylostoma caninum: A Comprehensive Review. [PDF]

open access: yesVet Med Sci
This review summarizes the emergence of anthelmintic resistance in Ancylostoma caninum, with a focus on drug classes affected, global prevalence and resistance mechanisms. Early detection and integrated control strategies are essential to combat its spread.
Sönmez Hİ   +3 more
europepmc   +2 more sources

Acute toxicity events of ivermectin in chicks’ model [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2022
Ivermectin is a very safe drug; however, there are many studies on its toxic effects in different animals due to sensitivity, misuse, or accidental overdose.
Tamara K. Al-Najmawi, Muna H. Al-Zubaidy
doaj   +1 more source

In vitro larvicidal activity of ivermectin and povidone-iodine against Oestrus ovis.

open access: yesPLoS ONE, 2021
PurposeTo assess the in vitro larvicidal activity of ivermectin and povidone-iodine (PVP-I) against Oestrus ovis, the most frequent cause of external ophthalmomyiasis.MethodsL1 O.
Giuseppe D'Amico Ricci   +6 more
doaj   +2 more sources

Ivermectin metabolites reduce Anopheles survival

open access: yesScientific Reports, 2023
Ivermectin mass drug administration to humans or livestock is a potential vector control tool for malaria elimination. The mosquito-lethal effect of ivermectin in clinical trials exceeds that predicted from in vitro laboratory experiments, suggesting ...
Kevin C. Kobylinski   +14 more
doaj   +1 more source

Current therapeutic applications and pharmacokinetic modulations of ivermectin [PDF]

open access: yesVeterinary World, 2019
Ivermectin is considered to be a wonder drug due to its broad-spectrum antiparasitic activity against both ectoparasites and endoparasites (under class of endectocide) and has multiple applications in both veterinary and human medicine.
Khan Sharun   +5 more
doaj   +1 more source

Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes

open access: yesMalaria Journal, 2023
Background Ivermectin (22,23-dihydroavermectin B1a: H2B1a) is an endectocide used to treat worm infections and ectoparasites including lice and scabies mites.
Charlotte Kern   +5 more
doaj   +1 more source

Integrated analysis reveals FOXA1 and Ku70/Ku80 as targets of ivermectin in prostate cancer

open access: yesCell Death and Disease, 2022
Ivermectin is a widely used antiparasitic drug and shows promising anticancer activity in various cancer types. Although multiple signaling pathways modulated by ivermectin have been identified in tumor cells, few studies have focused on the exact target
Shidong Lv   +7 more
doaj   +1 more source

Ivermectin as an adjunct treatment for hospitalized adult COVID-19 patients: A randomized multi-center clinical trial

open access: yesAsian Pacific Journal of Tropical Medicine, 2021
Objective: To evaluate different doses of ivermectin in adult patients with mild COVID-19 and to evaluate the effect of ivermectin on mortality and clinical consequences. Methods: A randomized, double-blind, placebo-controlled, multicenter clinical trial
Morteza Shakhsi Niaee   +14 more
doaj   +1 more source

Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode.

open access: yesPLoS Pathogens, 2022
The antiparasitic drug ivermectin plays an essential role in human and animal health globally. However, ivermectin resistance is widespread in veterinary helminths and there are growing concerns of sub-optimal responses to treatment in related helminths ...
Roz Laing   +12 more
doaj   +1 more source

Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study

open access: yesParasites & Vectors, 2021
Background Despite remarkable success obtained with current malaria vector control strategies in the last 15 years, additional innovative measures will be needed to achieve the ambitious goals for malaria control set for 2030 by the World Health ...
Patricia Nicolas   +7 more
doaj   +1 more source

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