Results 1 to 10 of about 67,505 (283)

Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen

Journal of Antibiotics, 2020
Ivermectin proposes many potentials effects to treat a range of diseases, with its antimicrobial, antiviral, and anti-cancer properties as a wonder drug. It is highly effective against many microorganisms including some viruses.
Fatemeh Heidary, Reza Gharebaghi
exaly   +2 more sources

Ivermectin synergizes sorafenib in hepatocellular carcinoma via targeting multiple oncogenic pathways

Pharmacology Research & Perspectives, 2022
Advanced hepatocellular carcinoma (HCC) results in generally poor clinical outcomes and necessitates better therapeutic strategies. Ivermectin, which is an existing anti‐parasitic drug, has been recently identified as a novel anti‐cancer drug.
Haofeng Lu, Lin Zhou, Hongping Zuo, Wenjin Le, Jianfei Hu, Tiequan Zhang, Mi Li, Yufeng Yuan   +7 more
doaj   +2 more sources

Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines

American Journal of Therapeutics, 2021
Background: Repurposed medicines may have a role against the SARS-CoV-2 virus. The antiparasitic ivermectin, with antiviral and anti-inflammatory properties, has now been tested in numerous clinical trials.
Andrew Bryant, Sarah R Hill
exaly   +2 more sources

Transcriptomic analyses implicate neuronal plasticity and chloride homeostasis in ivermectin resistance and response to treatment in a parasitic nematode.

PLoS Pathogens, 2022
The antiparasitic drug ivermectin plays an essential role in human and animal health globally. However, ivermectin resistance is widespread in veterinary helminths and there are growing concerns of sub-optimal responses to treatment in related helminths ...
Roz Laing, Stephen R Doyle, Jennifer McIntyre, Kirsty Maitland, Alison Morrison, David J Bartley, Ray Kaplan, Umer Chaudhry, Neil Sargison, Andy Tait, James A Cotton, Collette Britton, Eileen Devaney   +12 more
doaj   +2 more sources

Evaluation of in vitro drug-drug interactions of ivermectin and antimalarial compounds [PDF]

Malaria Journal
Background Ivermectin is lethal to Anopheles mosquitoes and a novel approach to malaria transmission control. Ivermectin could be co-administered with antimalarial drugs in mass drug administration, seasonal malaria chemoprevention, or other ...
Phornpimon Tipthara, Rattawan Kullasakboonsri, Kevin C. Kobylinski, Joel Tarning   +3 more
doaj   +2 more sources

Death caused by transdermal ivermectin poisoning: A case report and literature review [PDF]

Journal of International Medical Research
Ivermectin is a classic antiparasitic drug that is widely used around the world. After the outbreak of coronavirus disease 2019, many studies have reported the potential effectiveness of ivermectin against coronavirus disease 2019; however, it is not ...
He Yin, Peng-Shu Zhang, Yu Chen, Bing-Bing Kong, Chen-Guang Zhang, Sheng Wu   +5 more
doaj   +2 more sources

The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro

Antiviral Research, 2020
Leon Caly, Michael Catton, David A Jans
exaly   +2 more sources

Context‐Dependent Effects of Ivermectin Residues on Dung Insects: Interactions With Environmental Stressors, Size, and Sex in a Sepsid Fly (Sepsis neocynipsea) [PDF]

Ecology and Evolution
Coprophagous insects frequently encounter veterinary medication residues that are excreted unmetabolized in livestock dung. These residues often negatively affect insect survival, reproduction, and ecosystem services and may contribute to the rapid ...
Jill Walker, Benjamin J. Mathews, Patrick T. Rohner   +2 more
doaj   +2 more sources

Acute toxicity events of ivermectin in chicks’ model [PDF]

Iraqi Journal of Veterinary Sciences, 2022
Ivermectin is a very safe drug; however, there are many studies on its toxic effects in different animals due to sensitivity, misuse, or accidental overdose.
Tamara K. Al-Najmawi, Muna H. Al-Zubaidy
doaj   +1 more source

Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Ivermectin is widely prescribed as a potential treatment for COVID-19 despite uncertainty about its clinical benefit. Objective To determine whether ivermectin is an efficacious treatment for mild COVID-19.
Eduardo López-Medina, Pio López, I. Hurtado, D. Dávalos, Oscar Ramírez, Ernesto Martinez, J. Diazgranados, J. Oñate, Hector Chavarriaga, S. Herrera, B. Parra, G. Libreros, R. Jaramillo, A. C. Avendaño, Dilian Toro, M. Torres, M. C. Lesmes, Carlos A Ríos, Isabella Caicedo   +18 more
semanticscholar   +1 more source